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Adalimumab
go.drugbank.com/drugs/DB00051ApprovedInvestigationalIt is produced by recombinant DNA technology using a mammalian cell expression system. … A biosimilar marketed as Hyrimoz, a high-concentration formulation of adalimumab, is also available.[L45643,L45818].
L-Acetylleucine
go.drugbank.com/drugs/DB16956ApprovedInvestigationalLevacetylleucine (L-acetylleucine) is a modified acetylated derivative of the amino acid [leucine]. The racemic (i.e. DL-) form has been available in France since 1957 for the treatment of vertigo. … [A264439] Observational studies in patients with Niemann-Pick disease type C (NPC) suggested a beneficial symptomatic as well as neuroprotective disease-modifying effect of the DL-form of N-acetylleucine
Technetium Tc-99m pertechnetate
go.drugbank.com/drugs/DB09314ApprovedInvestigationalPertechnetate has a wide variety of uses within nuclear medicine as it distributes within the body to a similar extent as iodine. … This is normally supplied in a hospital setting through the use of a technetium-99m generator, whereby technetium exits the generator in the form of the pertechnetate ion, TcO4−, which can be extracted
Mixtures: GENERADOR DE SOLUCION INYECTABLE DE PERTECNETATO (99MTC) DE SODIO. 2-50GBQ, TECHNELITE® GENERADOR DE TECNECIO TC 99MCategories: Compounds used in a research, industrial, or household settingCitalopram
go.drugbank.com/drugs/DB00215ApprovedInvestigationalIt is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs. … [A261316] Citalopram was approved by the FDA in 1998 for the treatment of depression in adults 18 years or older.[L5230]
Categories: Monoamine Oxidase A SubstratesProducts: CITALOPRAM 1A PHARMA 10MG, CITALOPRAM 1A PHARMA 20MGBenzoic acid
go.drugbank.com/drugs/DB03793ApprovedInvestigationalThis leads to excretion of these amino acids and a decrease in ammonia levels. Recent research shows that sodium benzoate may be beneficial as an add-on therapy (1 gram/day) in schizophrenia. … Total Positive and Negative Syndrome Scale scores dropped by 21% compared to placebo.
Mixtures: Prosed/DSCategories: Compounds used in a research, industrial, or household settingFormic acid
go.drugbank.com/drugs/DB01942ApprovedInvestigationalIt is commonly used as a preservative and antibacterial agent in livestock feed.
Mixtures: Prenate DHA, Pre-Tabs DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPAAlbumin human
go.drugbank.com/drugs/DB00062ApprovedInvestigationalThis is a biosimilar drug to existing human serum albumin and was approved for a biological license at both 5% and 25% concentrations by the FDA on June 21, 2018 [L3101]. … Human albumin is a small globular protein (molecular weight: 66.5 kDa), consisting of a single chain of 585 amino acids organized in three repeated homolog domains (sites I, II, and III).
Heme iron polypeptide
go.drugbank.com/drugs/DB11067ApprovedMixtures: Vp-heme Ob DHA, HemeNatal OB plus DHALys-63-specific deubiquitinase BRCC36
go.drugbank.com/bio_entities/BE0009071TargetHumansMediates the specific 'Lys-63'-specific deubiquitination associated with the COP9 signalosome complex (CSN), via the interaction of the BRISC complex with the CSN complex (PubMed:19214193). … Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites
Synonyms: BRCA1-A complex subunit BRCC36, BRISC complex subunit BRCC36Fosnetupitant
go.drugbank.com/drugs/DB14019ApprovedInvestigationalFosnetupitant is the pro-drug form of netupitant [FDA label]. … Food and Drug Administration (FDA) and the Swiss company Helsinn approved the intravenous formulation of AKYNZEO® (NEPA, a fixed antiemetic combination of fosnetupitant, 235mg, and palonosetron, 0.25mg