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Roxadustat
go.drugbank.com/drugs/DB04847ApprovedInvestigationalRoxadustat is a first-in-class hypoxia-inducible factor prolyl hydroxylase inhibitor used to treat anemia associated with chronic kidney disease. … It works by reducing the breakdown of the hypoxia-inducible factor (HIF), which is a transcription factor that stimulates red blood cell production in response to low oxygen levels.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: Ernevod 100 mg Film Kaplı Tablet (12 adet), EVRENZO 100 MG FİLM KAPLI TABLET, 12 ADETNateglinide
go.drugbank.com/drugs/DB00731ApprovedApproximately one month of therapy is required before a decrease in fasting blood glucose is seen. Meglitnides may have a neutral effect on weight or cause a slight increase in weight. … In addition to reducing postprandial and fasting blood glucose, meglitnides have been shown to decrease glycosylated hemoglobin (HbA1c) levels, which are reflective of the last 8-10 weeks of glucose control
Mixtures: NAT-ALA 120/200 MG FILM KAPLI TABLET, 90 ADET, NAT-ALA 180/200 MG FILM KAPLI TABLET, 90 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesIsosorbide dinitrate
go.drugbank.com/drugs/DB00883ApprovedInvestigationalA vasodilator used in the treatment of angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action.
Categories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 Enzyme InhibitorsSynonyms: D-Isosorbide dinitrateCalcium
go.drugbank.com/drugs/DB01373ApprovedInvestigationalNutraceuticalThe best-absorbed form of calcium from a pill is a calcium salt like carbonate or phosphate. Calcium gluconate and calcium lactate are absorbed well by pregnant women. … The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions.
Mixtures: OSSOFORTIN A 70 MG+1200 MG/800 IU TEDAVİ PAKETİ, 4+24 ADET, Calcium With Vitamin D 200 Mg/160 IuCategories: ascorbic acid (vit C) and calciumErbumine
go.drugbank.com/drugs/DB18019InvestigationalSynonyms: Aurora a kinase inhibitor ly3295668, 1-((3-chloro-2-fluorophenyl)methyl)-4-((3-fluoro-6-((5-methyl-1h-pyrazol-3-yl)amino)-2-pyridinyl)methyl)-2-methyl-, (2r,4r)-,4-piperidinecarboxylic acidCategories: Heterocyclic Compounds, 1-RingIron protein succinylate
go.drugbank.com/drugs/DB11209ApprovedMixtures: KOMFER FOL 40 MG/185 MCG ORAL COZELTI, 20 FLK., FERPLEX FOL 40 MG + 0.185 MG/15 ML ORAL ÇÖZELTİ, 10 ADETProducts: KOMFER 40 MG ORAL ÇÖZELTİ, 15 ML X 20 FLAKON, KOMFER 40 MG ORAL ÇÖZELTİ, 15 ML X 10 FLAKONUdenafil
go.drugbank.com/drugs/DB06267ApprovedUdenafil is a new phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED). It has been approved in South Korea and will be marketed under the brand name Zydena.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ZYDENA 100 MG FILM TABLET, 2 ADET, ZYDENA 100 MG FILM TABLET, 4 ADETVecuronium
go.drugbank.com/drugs/DB01339ApprovedInvestigationalA non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. … Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or
Categories: P-glycoprotein substratesProducts: BROCURIX 10 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE, BLOK-L 10 MG IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 1 ADETMilrinone
go.drugbank.com/drugs/DB00235ApprovedInvestigationalHeart failure is a multifactorial condition that affects roughly 1-2% of the adult population. … [A228323] Milrinone is a second-generation bipyridine phosphodiesterase (PDE) inhibitor created through chemical modification of [amrinone].
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingSynonyms: 1,6-Dihydro-2-methyl-6-oxo(3,4'-bipyridine)-5-carbonitrileSuccinylcholine
go.drugbank.com/drugs/DB00202ApprovedInvestigationalSuccinylcholine is a depolarizing skeletal muscle relaxant consisting of two molecules of the endogenous neurotransmitter [acetylcholine] (ACh) linked by their acetyl groups. … [A19054] It has been widely used for over 50 years,[A299] most commonly in its chloride salt form, as a means of neuromuscular blockade during intubation and surgical procedures.
Synonyms: 2,2'-[(1,4-dioxobutane-1,4-diyl)bis(oxy)]bis(N,N,N-trimethylethanaminium)Products: ETHICHOLINE INJECTION 100 mg/2 ml, QUELICIN 1000 MG/10 ML