Vecuronium

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DB01339ApprovedInvestigationalSmall moleculeNeuromuscular Blocking Agents Neuromuscular-Blocking Agents (Nondepolarizing)

Vecuronium is a nondepolarizing neuromuscular blocking agent used to relax muscles or as an adjunct in general anesthesia during surgical procedures. Monoquaternary homolog of pancuronium.

Mechanism: Vecuronium is a bisquaternary nitrogen compound that acts by competitively binding to nicotinic cholinergic receptors. The binding of vecuronium decreases the opportunity for acetylcholine to bind to the nicotinic receptor at the postjunctional membrane of the myoneural junction. As a result, depolarization is prevented, calcium ions are not released and muscle contraction does not occur.
Curator reviewed
Primary indication: Vecuronium is a muscle relaxing agent and is used as an adjunct in general anesthesia.Curator reviewed · 3 structured indications
Formula / weight: C₃₄H₅₇N₂O₄ · 557.8274 g/mol (avg)
First approval: Canada, 2004 · United States, 1984

Resolves to

Compound

UNII5438723848CAS86029-43-8ChEMBLCHEMBL1201219ChEBI9939PubChem39765KEGGC07553

Clinical / RWD

RxNorm71535ATCM03AC03PharmGKBPA164748865

Structure

InChIKeyBGSZAXLLHYERSY-XQIGCQGXSA-NSMILES

[H][C@@]12C[C@@H]([C@H](OC(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])C[C@H](OC(C)=O)[C@H](C[C@]12C)N1CCCCC1)[N+]1(C)CCCCC1

Targets

Q15822CHRNA2

Transporters

P08183ABCB1

What you can answer from here — as of September 13, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1TransporterSubstrate / inhibitor direction, not just membership

Listed above

1,121Drug interactionsStructured to mechanism, not free text

22Clinical trialsPhase, status and sponsor resolved per trial

3Structured indicationsCondition, population, route and combination as fields, not prose

76Marketed productsAcross 6 countries and 39 labellers

1ATC codeIncluding every combination product, plus 18 drug categories

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with Vecuronium, and which of those have an active Phase 3 trial?

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