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Tenofovir alafenamide
go.drugbank.com/drugs/DB09299ApprovedInvestigational[A178060] Both of these prodrugs were first created to cover the polar phosphonic acid group on tenofovir by using a novel oxycarbonyloxymethyl linkers to improve the oral bioavailability and intestinal … [L4388,L9010] Tenofovir alafenamide was developed by Gilead Sciences Inc and granted FDA approval on 5 November 2015.[L6271]
Categories: Antivirals used in combination for the treatment of HIV infectionsAtorvastatin
go.drugbank.com/drugs/DB01076ApprovedInvestigational[A181397, A181403] Atorvastatin was first synthesized in 1985 by Dr. Bruce Roth and approved by the FDA in 1996. … or angioplasty following a heart attack.
Categories: atorvastatin, amlodipine and ramipril, atorvastatin, acetylsalicylic acid and ramiprilProducts: ATORVASTATINA SANDOZ® 40 MG TABLETAS CON PELICULA, ATORVASTATINA20 MG COMPRIMIDOS CON CUBIERTA PELICULARCiclopirox
go.drugbank.com/drugs/DB01188ApprovedInvestigationalCiclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. … In particular, the agent is especially effective in treating Tinea versicolor.
Patiromer
go.drugbank.com/drugs/DB09263ApprovedInvestigationalThe chemical name for patiromer sorbitex calcium is cross-linked polymer of calcium 2-fluoroprop-2-enoate with diethenylbenzene and octa-1,7-diene, combination with D-glucitol. … Each gram of patiromer is equivalent to a nominal amount of 2 grams of patiromer sorbitex calcium.
Categories: Compounds used in a research, industrial, or household setting, Potassium Ion Binding ActivitySulisobenzone
go.drugbank.com/drugs/DB11185ApprovedSulisobenzone is approved by the FDA in concentrations of up to 10% and in Canada, is approved by Health Canada at the same concentrations [F38]. … As a group, benzophenones may be used to delay photodegradation or extend shelf life in toiletries and plastic surface coatings [L2671].
Mixtures: Rayito de Sol, Rayito de SolInternational brands: Uvinul D 5030Edetic acid
go.drugbank.com/drugs/DB00974ApprovedInvestigationalVet approvedA chelating agent (chelating agents) that sequesters a variety of polyvalent cations. It is used in pharmaceutical manufacturing and as a food additive.
Categories: Compounds used in a research, industrial, or household settingSynonyms: N,N'-1,2-Ethane diylbis-(N-(carboxymethyl)glycine), EDTA, ion(4-)Serine
go.drugbank.com/drugs/DB00133ApprovedInvestigationalNutraceuticalA non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from glycine or threonine. It is involved in the biosynthesis of purines; pyrimidines; and other amino acids.
Mixtures: SOLUCION DP-AMINE, TRAVASOL PLUS 15% LIBRE DE BISULFITOPolihexanide
go.drugbank.com/drugs/DB12277ApprovedInvestigational[A1351] It is effective against a wide range of Gram-positive and Gram-negative bacteria. … [A1351,A273908] Polihexanide is approved in Europe under the name Akantior for the treatment of _Acanthamoeba_ keratitis, an ocular infection caused by the _Acanthamoeba_ parasite.
Categories: Compounds used in a research, industrial, or household settingSelenious acid
go.drugbank.com/drugs/DB11127ApprovedSelenium is a component of glutathione peroxidase enzyme, which protects cell components from oxidative damage due to peroxides produced during cellular metabolism [L1916]. … Interestingly, selenium is being studied as a potential therapy in the prevention or management of atherosclerosis [L1921].
Mixtures: DAILY-ONE 45 FILM TABLET, One Per Day Vitamin and Mineral Dietary SupplementNaloxone
go.drugbank.com/drugs/DB01183ApprovedInvestigationalVet approvedDue to its short duration of action, persons injected with naloxone should be monitored for responsiveness and potentially injected a second time or taken to the hospital. … [L33714,L33719] Naloxone was granted FDA approval on 13 April 1971.[L33709]
Synonyms: 17-allyl-3,14-dihydroxy-4,5α-epoxymorphinan-6-one, 1-N-Allyl-14-hydroxynordihydromorphinoneMixtures: TILIDIN HEXAL COMP D-PUMPE, Bupensan Duo 4 mg/1 mg-Sublingualtabletten