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Pralidoxime
go.drugbank.com/drugs/DB00733ApprovedInvestigationalVet approvedPralidoxime is an antidote to organophosphate pesticides and chemicals. Organophosphates bind to the esteratic site of acetylcholinesterase, which results initially in reversible inactivation of the enzyme. If given within 24 hours,after...
Products: PAM-A INJECTION 500 mg/ampoule, CONTRATHION % 2 FLAKON, 10 ADETRamelteon
go.drugbank.com/drugs/DB00980ApprovedInvestigationalRamelteon has not been shown to produce dependence and has shown no potential for abuse.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: ROZEREST 8 MG FİLM KAPLI TABLET, 10 ADET, RAMELDA 8 MG FILM KAPLI TABLET,10 ADETAlitretinoin
go.drugbank.com/drugs/DB00523ApprovedIt has also been approved for use in promyelocytic leukemia (leukemia, promyelocytic, acute). … Tretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth; and embryonic development. An excess of tretinoin can be teratogenic.
Products: Alitretan 10 mg Kapseln, TOCTINO 10 mg WeichkapselnOxytocin
go.drugbank.com/drugs/DB00107ApprovedInvestigationalVet approved[A229108,A229113] It is estimated that labor induction with oxytocin is used in almost 10% of deliveries globally. … [A229008,A228593] In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named Vincent du Vigneaud; he was later recognized with a Nobel prize for his work.
Mixtures: Bakumokon 5% MinoxidilProducts: Oxyla 10 IU/mL Injection, SYNPİTAN FORTE 5 I.U./ML I.M./I.V. ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL, 50 ADETSomatostatin
go.drugbank.com/drugs/DB09099ApprovedInvestigationalWithdrawnThe actions of somatostatin are mediated via signalling pathways of G protein-coupled somatostatin receptors. … well as treat acromegaly [T28].
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: SOMATOSTATIN EUMEDICA 250 MCG IV INFÜZYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET, STILAMIN 3000 FOR INJECTION 3 mg/ampouleSotorasib
go.drugbank.com/drugs/DB15569ApprovedInvestigationalSotorasib, also known as AMG-510, is an acrylamide-derived KRAS inhibitor developed by Amgen. … [L34288] This mutation makes up >50% of all KRAS mutations.[A187550] Mutant KRAS discovered in 1982 but was not considered a druggable target until the mid-2010s.
Categories: RAS GTPase Inhibitors, Cytochrome P-450 SubstratesProducts: LUMAKRAS 120 MG FİLM KAPLI TABLET, 240 ADETParicalcitol
go.drugbank.com/drugs/DB00910ApprovedInvestigationalParicalcitol has been used to reduce parathyroid hormone levels. Paricalcitol is indicated for the prevention and treatment of secondary hyperparathyroidism associated with chronic renal failure.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: PAKSİTU 10 MCG/2 ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADET, RECHROSİTOL 10 MCG/ML I.V. ENJEKSİYONLUK ÇÖZELTİ, 5 ADETHuman Rho(D) immune globulin
go.drugbank.com/drugs/DB11597ApprovedIt was approved by FDA as treatment for suppression of rhesus (Rh) isoimmunization or chronic immune thrombocytopenic purpura (ITP) in adults. … Human Rho(D) immune globulin is a medicine given by intramuscular or intravenous injection that is used to prevent the immunological condition known as Rh disease (or hemolytic disease of newborn).
Categories: Human Immunoglobulin GProducts: RHOPHYLAC 300 MCG/2 ML (1500 IU) IM/IV KULLANIMA HAZIR ENJEKTÖRDE ENJEKSİYONLUK ÇÖZELTİ, IMMUNORHO 300 MCG (1500 IU)/ 2 ML IM ENJEKSIYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADETAnifrolumab
go.drugbank.com/drugs/DB11976ApprovedInvestigational[A237054] Anifrolumab has also been investigated for the treatment of Scleroderma.[A237044] Anifrolumab was granted FDA approval on 30 July 2021.[L34929] … erythematosus, but so far only anifrolumab has been approved.
Products: Saphnelo 300 mg/2 mL İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 1 ADETVemurafenib
go.drugbank.com/drugs/DB08881ApprovedInvestigational[A31270] Vemurafenib was co-developed by Roche and Plexxikon and it obtained its FDA approval on August 17, 2011, under the company Hoffmann La Roche.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersProducts: ZELBORAF 240 MG FILM KAPLI TABLET ,56 FILM KAPLI TABLET, ZELBORAF ® TABLETAS LACADAS DE 240 MG