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Dulaglutide
go.drugbank.com/drugs/DB09045ApprovedInvestigationaltherapy to diet and exercise in the management of 2 diabetes (T2DM). … It is the first T2DM drug approved to reduce major adverse cardiovascular events (MACE) risk in primary and secondary prevention populations.[L34665]
Products: TRULICITY® 1.5 MG/0.5 ML, TRULICITY® 0.75 MG/0.5 MLChlorphenoxamine
go.drugbank.com/drugs/DB09007ApprovedWithdrawnIt is an antihistamine and anticholinergic used to treat itching as well as for its antiparkinsonian effect.
Mixtures: SISTRAL C DRAJE , 20 ADETProducts: SISTRAL 10 MG/ML I.V./I.M. ENJEKSİYONLUK ÇÖZELTİ, 6 ADET, SYSTRAL JEL, 20 GHydroxychloroquine
go.drugbank.com/drugs/DB01611ApprovedInvestigationalHydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. Hydroxychloroquine is an aminoquinoline like chloroquine. It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesSynonyms: 7-chloro-4-[5-(N-ethyl-N-2-hydroxyethylamino)-2-pentyl]aminoquinolineUrofollitropin
go.drugbank.com/drugs/DB00094ApprovedVet approvedWithdrawnUrofollitropin may also be used to cause the ovary to produce several follicles, which can then be harvested for use in gamete intrafallopian transfer (GIFT) or in vitro fertilization (IVF). … The alpha subunit is glycosylated at Asn 51 and Asn 78 while the beta subunit is glycosylated at Asn 7 and Asn 24.
Mixtures: Fertinorm Hp 150 - Pws Diluent Im ScProducts: FOSTİMON 150 IU ENJEKSİYONLUK LİYOFİLİZE TOZ (10 FLAKON + 10 AMPUL), FOSTİMON 75 IU ENJEKSİYONLUK LİYOFİLİZE TOZ (10 FLAKON + 10 AMPUL)Benznidazole
go.drugbank.com/drugs/DB11989ApprovedInvestigationalBenznidazole was granted accelerated approval for the treatment of Chagas disease in children 2-12 years of age by the FDA on August 29, 2017.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: ABALEA ®100 MGPentoxyverine
go.drugbank.com/drugs/DB11186ApprovedWithdrawn[L43942] Other forms of pentoxyverine citrate continue to be marketed. … Pentoxyverine acts on sigma-1 receptors, as well as kappa and mu-opioid receptors. The FDA withdrew the use of all oral gel drug products containing pentoxyverine citrate.
Mixtures: GAYABEN 150 ML SURUPProducts: PENTOXYVERIN AL 1.35 MG/ML, Mucomat Hustenstiller 2,13 mg/ml Lösung zum EinnehmenTrimetazidine
go.drugbank.com/drugs/DB09069ApprovedInvestigational[A233255,A233260] Acidic conditions, caused by anaerobic metabolism and fatty acid oxidation, in response to myocardial ischemia, activate sodium-hydrogen and sodium-calcium antiport systems. … Trimetazidine is a piperazine derivative indicated for the symptomatic treatment of stable angina pectoris in patients inadequately controlled or intolerant to first line therapies.
International brands: Vastarel MRProducts: SITOREL 20 MG FILM TABLET, 60 ADET, VASOFIX 20 MG FILM TABLET, 60 ADETSotorasib
go.drugbank.com/drugs/DB15569ApprovedInvestigationalSotorasib, also known as AMG-510, is an acrylamide-derived KRAS inhibitor developed by Amgen. … [L34288] This mutation makes up >50% of all KRAS mutations.[A187550] Mutant KRAS discovered in 1982 but was not considered a druggable target until the mid-2010s.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersProducts: LUMAKRAS 120 MG FİLM KAPLI TABLET, 240 ADETEthionamide
go.drugbank.com/drugs/DB00609ApprovedInvestigationalWithdrawnA second-line antitubercular agent that inhibits mycolic acid synthesis. It also may be used for treatment of leprosy. (From Smith and Reynard, Textbook of Pharmacology, 1992, p868)
Products: ETYOMİD 250 MG DRAJE, 500 ADET, ETYOMID 250 MG DRAJE, 50 ADET