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Displaying results 1141 - 1150 of 10000 in total
  1. Drug

    Sulfamethoxazole

    go.drugbank.com/drugs/DB01015
    ApprovedInvestigational

    Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria. … [L11830] In this combination, sulfamethoxazole is useful for the treatment of a variety of bacterial infections, including those of the urinary, respiratory, and gastrointestinal tracts.

    Mixtures: MEDIPRIM F (R) TABLETA, MEDIPRIM F (R) TABLETACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors
  2. Drug

    Hydrocortisone probutate

    go.drugbank.com/drugs/DB14543
    ApprovedVet approved

    Categories: Corticosteroids, Moderately Potent (Group II), Cytochrome P-450 Substrates
  3. Drug

    SRP-9005

    go.drugbank.com/drugs/DB17958
    Investigational

    SRP-9005 is a rAAVrh74 vector containing a codon-optimized human SGCG transgene. … Developed by the Kurt+Peter Foundation and Sarepta Therapeutics, it is being investigated for the treatment of Limb-girdle muscular dystrophy (LGMD) type 2C/R5.[A260142]

  4. Drug

    Frangula purshiana bark

    go.drugbank.com/drugs/DB15478
    Approved

    Mixtures: Cholasyn II, Le 100 B
  5. Drug

    Tividenofusp alfa

    go.drugbank.com/drugs/DB17628
    ApprovedInvestigational

    Hunter syndrome is a rare, X-linked lysosomal storage disorder caused by a deficiency in the enzyme iduronate-2-sulfatase (IDS), which leads to the toxic accumulation of glycosaminoglycans (GAGs) throughout … Tividenofusp alfa is a first-in-class, brain-penetrant enzyme replacement therapy (ERT) indicated for the treatment of Mucopolysaccharidosis type II (MPS II), also known as Hunter syndrome [L56097, L56099

    Synonyms: 676>S, L 678>A, Y, - L-iduronate sulfate sulfatase, EC:3.1.6.13) pro-protein (1-525), fused via the peptide linker 526 GGGGS 530 to a human immunoglobulin G1 C-terminal Fc fragment (531-757) variant (L 544>A, L 545>A, T
  6. Drug

    SD118

    go.drugbank.com/drugs/DB05207
    Experimental

    SD118 was previously under investigation in Japan for a different indication and now, following re-profiling and evaluation in experimental animal models, has demonstrated its potential as a new oral therapy

  7. Drug

    Festuca pratensis pollen

    go.drugbank.com/drugs/DB10370
    Approved

    Festuca pratensis pollen is the pollen of the Festuca pratensis plant. Festuca pratensis pollen is mainly used in allergenic testing.

    Mixtures: Mixture of Six Standardized Grasses, 6 Grass Mix
  8. Drug

    Adenine

    go.drugbank.com/drugs/DB00173
    ApprovedInvestigationalNutraceutical

    A purine base and a fundamental unit of adenine nucleotides.

    Mixtures: IMUFLEX WB-SP Blood Bag System with Integral Whole Blood Leukocyte Reduction Filter (Saving Platelets) with Diversion Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) and OPTISOL (AS-5, IMUFLEX WB-SP Blood Bag System with Integral Whole Blood Leukocyte Reduction Filter (Saving Platelets) with Diversion Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) and OPTISOL (AS-5Categories: Heterocyclic Compounds, 2-Ring
  9. Drug

    Succinic acid

    go.drugbank.com/drugs/DB00139
    ApprovedInvestigationalNutraceutical

    It is also used in foods as a sequestrant, buffer, and a neutralizing agent. … A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters.

    Mixtures: Se-Vate 21/7, FeRiva 21 7
  10. Drug

    Berzosertib

    go.drugbank.com/drugs/DB11794
    Investigational

    Berzosertib (VX-970) has been used in trials studying the treatment of Ovarian Neoplasms, Ovarian Serous Tumor, Adult Solid Neoplasm, Advanced Solid Tumor, and Advanced Solid Neoplasm, among others.

    Categories: Heterocyclic Compounds, 1-Ring