This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Frangula purshiana bark
DrugBank Accession Number
DB15478
Background

Not Available

Type
Biotech
Groups
Approved, Experimental
Synonyms
  • Aromatic cascara fluidextract
  • Aromatic cascara sagrada fluid extract
  • Bearberry bark
  • Carscara bitterless extract
  • Cascara bitterless bark extract
  • Cascara buckthorn bark
  • Cascara fluidextract, aromatic
  • Cascara sagrada
  • Cascara sagrada bark
  • Cascara sagrada extract
  • Cascara sagrada fluidextract
  • Chittambark
  • Chittem bark
  • Frangula purshiana bark
  • Frangula purshiana bark extract
  • Pursh's buckthorn bark
  • Rhamni purshianae cortex
  • Rhamnus purshiana
  • Rhamnus purshiana bark
  • Rhamnus purshiana bark dry extract
  • Rhamnus purshiana bark extract
  • Rhamnus purshiana stem bark
  • Sacred bark
External IDs
  • B2340
  • Fema no. 2253

Pharmacology

Indication

Not Available

Pharmacology
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Associated Conditions
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AcetazolamideThe risk or severity of adverse effects can be increased when Acetazolamide is combined with Frangula purshiana bark.
AclidiniumThe therapeutic efficacy of Frangula purshiana bark can be decreased when used in combination with Aclidinium.
AlfentanilThe therapeutic efficacy of Frangula purshiana bark can be decreased when used in combination with Alfentanil.
AmantadineThe therapeutic efficacy of Frangula purshiana bark can be decreased when used in combination with Amantadine.
AmilorideThe risk or severity of adverse effects can be increased when Amiloride is combined with Frangula purshiana bark.
AmiodaroneThe therapeutic efficacy of Frangula purshiana bark can be decreased when used in combination with Amiodarone.
AmitriptylineThe therapeutic efficacy of Frangula purshiana bark can be decreased when used in combination with Amitriptyline.
AmlodipineThe therapeutic efficacy of Frangula purshiana bark can be decreased when used in combination with Amlodipine.
AmobarbitalThe therapeutic efficacy of Frangula purshiana bark can be decreased when used in combination with Amobarbital.
AmoxapineThe therapeutic efficacy of Frangula purshiana bark can be decreased when used in combination with Amoxapine.
Interactions
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Food Interactions
Not Available

Products

Products2
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Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
Aromatic Cascara Sagrada CompoundLiquid1 g / mLOralD.C. Labs Limited1951-12-312003-07-11Canada flag
Biofant - 41mg/5mlLiquid41 mg / 5 mLOralLes Laboratoires Vachon Inc.1995-12-311997-08-08Canada flag
Cascara AromaticLiquid5 g / 10 mLOralIngram And Bell Inc.1953-12-311999-08-05Canada flag
Cascara Aromatic Liq 250mgLiquid250 mg / mLOralDawson Traders Ltd.1977-12-312006-03-22Canada flag
Cascara Aromatique ElixirLiquid33.3 g / 100 mLOralLab Valmo EnregistrÉ, Division Of Technilab Inc.1983-12-311999-09-17Canada flag
Cascara Fluid ExtLiquidOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1965-12-312000-07-27Canada flag
Cascara SagradaCapsule400 mg / capOralNatural Factors Nutritional Products Ltd.1998-10-212008-07-17Canada flag
Cascara SagradaCapsule450 mg / capOralSundown Vitamins2000-11-232002-08-09Canada flag
Cascara Sagrada 300mgCapsule100 mg / capOralGeneral Nutrition Canada Inc.1999-03-292005-08-05Canada flag
Cascara Sagrada 500mg - CapCapsule500 mg / capOralHealth Wise Nutrition Inc.1997-08-151998-08-25Canada flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Aid-lax TabFrangula purshiana bark (30 mg / tab) + Alloin (12 mg / tab) + Phenolphthalein (100 mg / tab) + Sodium taurocholate (60 mg / tab)TabletOralNobel Pharm Enr.1989-12-311997-07-31Canada flag
AlsilineFrangula purshiana bark (30 mg / tab) + Alloin (12 mg / tab) + Phenolphthalein (100 mg / tab) + Sodium taurocholate (60 mg / tab)TabletOralAlsi Cie Ltee1978-12-311997-08-08Canada flag
Bicholate LilasFrangula purshiana bark (30 mg) + Aloe vera leaf (12 mg) + Bisacodyl (5 mg) + Sodium taurocholate (60 mg)TabletOralSabex Inc1998-10-282009-11-24Canada flag
Bicholate Lilas TabFrangula purshiana bark (30 mg) + Alloin (12 mg) + Phenolphthalein (100 mg) + Sodium taurocholate (60 mg)TabletOralSabex Inc1991-12-311997-10-10Canada flag
Bilex TabFrangula purshiana bark (30 mg) + Alloin (12 mg) + Phenolphthalein (100 mg) + Sodium taurocholate (60 mg)TabletOralBiodo Enrg1978-12-311997-10-10Canada flag
C Ottways Lax TabFrangula purshiana bark (28 mg / tab) + Aloe vera leaf (132 mg / tab) + Capsicum (19 mg / tab) + Ginger (9 mg / tab) + Glycyrrhiza glabra (28 mg / tab) + Senna leaf (28 mg / tab)TabletOralC Ottway Herbalist1950-12-311997-06-13Canada flag
CholasynFrangula purshiana bark (50 mg) + Sennosides (12 mg)TabletOralRolmex International Inc.1998-06-292001-08-14Canada flag
Cholasyn IIFrangula purshiana bark (175 mg) + Senna leaf (25 mg)TabletOralRolmex International Inc.1983-12-312008-02-13Canada flag
Doulax TabFrangula purshiana bark (32.4 mg) + Phenolphthalein (97.2 mg)TabletOralLes Laboratoires Bio SantÉ Inc.1983-12-311998-01-14Canada flag
GeribileFrangula purshiana bark (600 mg / tab) + Senna leaf (25 mg / tab)TabletOralLes Produits Gerbex Inc.1999-02-232005-06-29Canada flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
4VBP01X99F
CAS number
8015-89-2

References

General References
Not Available
RxNav
1350209

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
SolutionOral
Powder, for solutionOral
Powder, for suspensionOral
Powder, for suspensionOral0.6 g
LiquidOral41 mg / 5 mL
PowderNot applicable1 kg/1kg
LiquidOral5 g / 10 mL
LiquidOral250 mg / mL
LiquidOral33.3 g / 100 mL
LiquidOral
CapsuleOral400 mg / cap
CapsuleOral450 mg / cap
CapsuleOral100 mg / cap
CapsuleOral500 mg / cap
CapsuleOral400 mg / tab
Capsule, coatedOral400 mg
TabletOral487.5 mg
TabletOral324 mg / tab
TabletOral325 mg
Tablet, coatedOral
SyrupOral
CapsuleOral80.5 mg / cap
LiquidOral325 mg / 30 mL
KitOral
TabletOral
LiquidOral1 g / mL
TabletOral200 mg / tab
TabletOral160 mg / tab
LiquidOral
CapsuleOral
TabletOral330 mg / tab
LiquidOral1.1664 g / 30 mL
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at August 30, 2019 15:40 / Updated at October 02, 2020 07:51