This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Frangula purshiana bark
- DrugBank Accession Number
- DB15478
- Background
Not Available
- Type
- Biotech
- Groups
- Approved, Experimental
- Synonyms
- Aromatic cascara fluidextract
- Aromatic cascara sagrada fluid extract
- Bearberry bark
- Carscara bitterless extract
- Cascara bitterless bark extract
- Cascara buckthorn bark
- Cascara fluidextract, aromatic
- Cascara sagrada
- Cascara sagrada bark
- Cascara sagrada extract
- Cascara sagrada fluidextract
- Chittambark
- Chittem bark
- Frangula purshiana bark
- Frangula purshiana bark extract
- Pursh's buckthorn bark
- Rhamni purshianae cortex
- Rhamnus purshiana
- Rhamnus purshiana bark
- Rhamnus purshiana bark dry extract
- Rhamnus purshiana bark extract
- Rhamnus purshiana stem bark
- Sacred bark
- External IDs
- B2340
- Fema no. 2253
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
- Contraindications & Blackbox Warnings
Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAcetazolamide The risk or severity of adverse effects can be increased when Acetazolamide is combined with Frangula purshiana bark. Aclidinium The therapeutic efficacy of Frangula purshiana bark can be decreased when used in combination with Aclidinium. Alfentanil The therapeutic efficacy of Frangula purshiana bark can be decreased when used in combination with Alfentanil. Amantadine The therapeutic efficacy of Frangula purshiana bark can be decreased when used in combination with Amantadine. Amiloride The risk or severity of adverse effects can be increased when Amiloride is combined with Frangula purshiana bark. Amiodarone The therapeutic efficacy of Frangula purshiana bark can be decreased when used in combination with Amiodarone. Amitriptyline The therapeutic efficacy of Frangula purshiana bark can be decreased when used in combination with Amitriptyline. Amlodipine The therapeutic efficacy of Frangula purshiana bark can be decreased when used in combination with Amlodipine. Amobarbital The therapeutic efficacy of Frangula purshiana bark can be decreased when used in combination with Amobarbital. Amoxapine The therapeutic efficacy of Frangula purshiana bark can be decreased when used in combination with Amoxapine. 
Identify potential medication risksEasily compare up to 40 drugs with our drug interaction checker.Get severity rating, description, and management advice.Learn more - Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Aromatic Cascara Sagrada Compound Liquid 1 g / mL Oral D.C. Labs Limited 1951-12-31 2003-07-11 Canada 
Biofant - 41mg/5ml Liquid 41 mg / 5 mL Oral Les Laboratoires Vachon Inc. 1995-12-31 1997-08-08 Canada Cascara Aromatic Liquid 5 g / 10 mL Oral Ingram And Bell Inc. 1953-12-31 1999-08-05 Canada Cascara Aromatic Liq 250mg Liquid 250 mg / mL Oral Dawson Traders Ltd. 1977-12-31 2006-03-22 Canada Cascara Aromatique Elixir Liquid 33.3 g / 100 mL Oral Lab Valmo EnregistrÉ, Division Of Technilab Inc. 1983-12-31 1999-09-17 Canada Cascara Fluid Ext Liquid Oral Stanley Pharmaceuticals, A Division Of Vita Health Products Inc. 1965-12-31 2000-07-27 Canada Cascara Sagrada Capsule 400 mg / cap Oral Natural Factors Nutritional Products Ltd. 1998-10-21 2008-07-17 Canada Cascara Sagrada Capsule 450 mg / cap Oral Sundown Vitamins 2000-11-23 2002-08-09 Canada Cascara Sagrada 300mg Capsule 100 mg / cap Oral General Nutrition Canada Inc. 1999-03-29 2005-08-05 Canada Cascara Sagrada 500mg - Cap Capsule 500 mg / cap Oral Health Wise Nutrition Inc. 1997-08-15 1998-08-25 Canada - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Aid-lax Tab Frangula purshiana bark (30 mg / tab) + Alloin (12 mg / tab) + Phenolphthalein (100 mg / tab) + Sodium taurocholate (60 mg / tab) Tablet Oral Nobel Pharm Enr. 1989-12-31 1997-07-31 Canada Alsiline Frangula purshiana bark (30 mg / tab) + Alloin (12 mg / tab) + Phenolphthalein (100 mg / tab) + Sodium taurocholate (60 mg / tab) Tablet Oral Alsi Cie Ltee 1978-12-31 1997-08-08 Canada Bicholate Lilas Frangula purshiana bark (30 mg) + Aloe vera leaf (12 mg) + Bisacodyl (5 mg) + Sodium taurocholate (60 mg) Tablet Oral Sabex Inc 1998-10-28 2009-11-24 Canada Bicholate Lilas Tab Frangula purshiana bark (30 mg) + Alloin (12 mg) + Phenolphthalein (100 mg) + Sodium taurocholate (60 mg) Tablet Oral Sabex Inc 1991-12-31 1997-10-10 Canada Bilex Tab Frangula purshiana bark (30 mg) + Alloin (12 mg) + Phenolphthalein (100 mg) + Sodium taurocholate (60 mg) Tablet Oral Biodo Enrg 1978-12-31 1997-10-10 Canada C Ottways Lax Tab Frangula purshiana bark (28 mg / tab) + Aloe vera leaf (132 mg / tab) + Capsicum (19 mg / tab) + Ginger (9 mg / tab) + Glycyrrhiza glabra (28 mg / tab) + Senna leaf (28 mg / tab) Tablet Oral C Ottway Herbalist 1950-12-31 1997-06-13 Canada Cholasyn Frangula purshiana bark (50 mg) + Sennosides (12 mg) Tablet Oral Rolmex International Inc. 1998-06-29 2001-08-14 Canada Cholasyn II Frangula purshiana bark (175 mg) + Senna leaf (25 mg) Tablet Oral Rolmex International Inc. 1983-12-31 2008-02-13 Canada Doulax Tab Frangula purshiana bark (32.4 mg) + Phenolphthalein (97.2 mg) Tablet Oral Les Laboratoires Bio SantÉ Inc. 1983-12-31 1998-01-14 Canada Geribile Frangula purshiana bark (600 mg / tab) + Senna leaf (25 mg / tab) Tablet Oral Les Produits Gerbex Inc. 1999-02-23 2005-06-29 Canada
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 4VBP01X99F
- CAS number
- 8015-89-2
References
- General References
- Not Available
- External Links
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Solution Oral Powder, for solution Oral Powder, for suspension Oral Powder, for suspension Oral 0.6 g Liquid Oral 41 mg / 5 mL Powder Not applicable 1 kg/1kg Liquid Oral 5 g / 10 mL Liquid Oral 250 mg / mL Liquid Oral 33.3 g / 100 mL Liquid Oral Capsule Oral 400 mg / cap Capsule Oral 450 mg / cap Capsule Oral 100 mg / cap Capsule Oral 500 mg / cap Capsule Oral 400 mg / tab Capsule, coated Oral 400 mg Tablet Oral 487.5 mg Tablet Oral 324 mg / tab Tablet Oral 325 mg Tablet, coated Oral Syrup Oral Capsule Oral 80.5 mg / cap Liquid Oral 325 mg / 30 mL Kit Oral Tablet Oral Liquid Oral 1 g / mL Tablet Oral 200 mg / tab Tablet Oral 160 mg / tab Liquid Oral Capsule Oral Tablet Oral 330 mg / tab Liquid Oral 1.1664 g / 30 mL - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
Drug created at August 30, 2019 15:40 / Updated at October 02, 2020 07:51