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Phosphatidyl serine
go.drugbank.com/drugs/DB00144ApprovedNutraceuticalPS has been shown to slow cognitive decline in animal models. … Because of the potentail cognitive benefits of phosphatidylserine, the substance is sold as a dietary supplement to people who believe they can benefit from an increased intake.
Synonyms: PSInternational brands: LifeExtension PS CapsMangafodipir
go.drugbank.com/drugs/DB06796ApprovedInvestigationalWithdrawnThis drug is made up of paramagnetic manganese (II) ions combined with the chelating agent _fodipir_ (dipyridoxyl diphosphate, DPDP). … Manganese absorption into the tissues that makes the normal tissue appear brighter in MRI is limited in abnormal or cancerous tissue.
Categories: Compounds used in a research, industrial, or household settingIsoflavone
go.drugbank.com/drugs/DB12007ApprovedInvestigationalWithdrawnSoybean is an exceptionally rich source of dietary isoflavones, where the average isoflavone content is 1-2 mg/gram [A33103]. … Isoflavone is found as one of constituents in oral over-the-counter dietary supplements indicated for improved bone mass density and body fat regulation.
Belantamab mafodotin
go.drugbank.com/drugs/DB15719ApprovedInvestigationalWithdrawnIn the meantime, belantamab mafodotin will be available for patients in the Risk Evaluation and Mitigation Strategy (REMS) program who can enrol in a compassionate use program. … Belantamab mafodotin, or GSK2857916, is an afucosylated monoclonal antibody that targets B cell maturation antigen conjugated to the microtubule disrupter monomethyl auristatin-F (MMAF).
Clobazam
go.drugbank.com/drugs/DB00349ApprovedIllicitInvestigational[A521,A522] In October 21, 2011, the FDA approved clobazam as an adjunctive treatment for seizures associated with Lennox-Gastaut syndrome in adults and children aged two years and older. … [A256968,A256973] Clobazam has been marketed as an anxiolytic since 1975 and an anticonvulsant since 1984.
Categories: GABA-A Receptor AgonistsPromestriene
go.drugbank.com/drugs/DB12487InvestigationalPromestriene (3-propyl ethyl, 17B-methyl estradiol) has been used in trials studying the prevention of Hypospadias. It is a synthetic estrogen analog, which is used in topical estrogen therapy. … It has been also studied in phase III of the clinical trial in the post-operative patients with hypospadias.
Categories: Estradiol CongenersRelapsed Marginal Zone Lymphoma
go.drugbank.com/conditions/DBCOND0092875Synonyms: Relapsed Marginal Zone LymphomaPalovarotene
go.drugbank.com/drugs/DB05467Approved[A244920] The ossification occurring as a result of FOP is insidious and cumulative and is provoked during flare-ups or in response to injury. … Treatment options for patients with FOP are extremely limited, although there has been substantial recent interest in novel treatments for this disease.
Categories: Retinoic Acid Receptor gamma, agonistsDexpanthenol
go.drugbank.com/drugs/DB09357ApprovedInvestigationalDexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. … Dexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that are important for protein metabolism
Mixtures: Trovite IV Injection, Daily all in one ampleProducts: Perfect Pore Clean I, PAN OPHTAL GELClozapine
go.drugbank.com/drugs/DB00363ApprovedInvestigationalClozapine is a tricyclic dibenzodiazepine, classified as an atypical antipsychotic agent. … [A185747] However, its promiscuity toward the muscarinic and adrenergic receptors can result in other side effects, notably gastrointestinal hypomotility and orthostatic hypotension. [L905,A215552].
Categories: Adrenergic alpha-1 Receptor Antagonists, Serotonin Receptor Antagonists