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Oxybuprocaine
go.drugbank.com/drugs/DB00892ApprovedInvestigationalOxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and otolaryngology. … Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions.
Mixtures: AMIGDAL-B®, BUCALIV® TABLETA MASTICABLESynonyms: 4-Amino-3-n-butoxy-benzoesäure-diäthylaminoäthylester, 4-Amino-3-butoxy-2-(diethylamino)ethyl ester benzoic acidAbatacept
go.drugbank.com/drugs/DB01281ApprovedInvestigational[L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it is a homodimer of two homologous polypeptide chains of 357 amino acids each … It is produced through recombinant DNA technology in mammalian CHO cells. The drug has activity as a selective co-stimulation modulator with inhibitory activity on T lymphocytes.
Categories: Selective T Cell Costimulation ModulatorProducts: ORENCIA Injection 125mg/ml in Prefilled Syringe, ORENCIA® SOLUCION INYECTABLE PARA ADMINISTRACION SUBCUTÁNEA 125 MG/MLMoxifloxacin
go.drugbank.com/drugs/DB00218ApprovedInvestigationalMoxifloxacin is a synthetic fluoroquinolone antibiotic agent. … Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.
Mixtures: TQ OFTAMOX D UD®, MOFLAG DCategories: Topoisomerase II Inhibitors, 4-QuinolonesRevakinagene taroretcel
go.drugbank.com/drugs/DB05344ApprovedInvestigational[A265115] On March 6, 2025, FDA approved revakinagene taroretcel for the treatment of idiopathic macular telangiectasia type 2. … (rhCNTF) (NTC-201-6A cell line) for surgical intravitreal placement.
Synonyms: An allogeneic human adult retinal pigment epithelial (RPE) cell line stably transfected with a plasmid, Allogeneic human adult retinal pigment epithelial (RPE) cell line stably transfected with a plasmid encoding human ciliary neurotrophic factor (CNTF).Mirtazapine
go.drugbank.com/drugs/DB00370ApprovedInvestigational[A178144,L6160] In addition to its beneficial effects in depression, mirtazapine has been reported to be efficacious in the off-label management of various other conditions. … Mirtazapine is a tetracyclic _piperazino-azepine_ antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesSynonyms: 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepine, 6-AzamianserinClopidogrel
go.drugbank.com/drugs/DB00758ApprovedInvestigationalin recent MI, stroke, or established peripheral arterial disease,[L7213] It has been shown to be superior to [aspirin] in reducing cardiovascular outcomes in patients with cardiovascular disease and … Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke.
Mixtures: CO-DEGREGAN, ATELIT-DUO® 75/100 MG TABLETASCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesFluticasone propionate
go.drugbank.com/drugs/DB00588ApprovedInvestigationalFluticasone propionate is a synthetic glucocorticoid[F4355,F4358][FDA Label]. … Fluticasone propionate was first approved in 1990[L5962].
Mixtures: DYMISTA D, SERECOR® FORTE DPI 500Categories: Agents to Treat Airway Disease, P-glycoprotein substratesTorasemide
go.drugbank.com/drugs/DB00214ApprovedInvestigationalTorasemide is a high-ceiling loop diuretic.[A174463] Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. … [A319] Torasemide was first approved for clinical use by the FDA in 1993.[L5257]
Categories: combinations of sulfonamides, Increased Diuresis at Loop of HenleSynonyms: N-(((1-Methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide, 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)ureaExametazime
go.drugbank.com/drugs/DB11179ApprovedIt is used in the detection of altered regional cerebral perfusion and for the radiolabeling of autologous leukocytes. … It acts as a chelating agent for the radioisotope technetium-99m to form a cationic complex.
Products: CERETEC TM INJ (SINGLE DOSE UNIT), CERETEC ESTABILIZADO KIT DE 500 MICROGRAMOS PARA PREPARACIÓN RADIOFARMACÉUTICATeriflunomide
go.drugbank.com/drugs/DB08880ApprovedInvestigationalIt is marketed under the name Aubagio® and is indicated for the treatment of multiple sclerosis, specifically relapsing forms. … Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis.
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersSynonyms: (Z)-2-cyano-alpha,alpha,alpha-trifluoro-3-hydroxy-p-crotonotoluidide