Search
A disintegrin and metalloproteinase with thrombospondin motifs 5
go.drugbank.com/bio_entities/BE0003730TargetHumansPlays a role in embryonic development, including limb and cardiac morphogenesis, and skeletal muscle development through its VCAN remodeling properties.
Polypeptides: A disintegrin and metalloproteinase with thrombospondin motifs 5Synonyms: A disintegrin and metalloproteinase with thrombospondin motifs 11Pasireotide
go.drugbank.com/drugs/DB06663ApprovedInvestigationalPasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Synonyms: cyclo((4R)-4-(2-aminoethylcarbamoyloxy)-L-prolyl-L-phenylglycyl-D-tryptophyl-L-lysyl-4-O-benzyl-L-tyrosyl-L- phenylalanyl-)International brands: Signifor LARMetformin
go.drugbank.com/drugs/DB00331ApprovedInvestigationalIt is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and a clinically significant reduction of plasma fasting insulin levels. … Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.
Mixtures: VELMETIA LP, Vildagliptin/Metformin 1A Pharma 50 mg/850 mg – FilmtablettenCategories: Drugs Used in Diabetes, MATE 1 SubstratesAloe vera flower
go.drugbank.com/drugs/DB14254ApprovedAloe vera flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: Barbatos Aloe Flower, Li Hui HuaPotassium voltage-gated channel subfamily A member 1
go.drugbank.com/bio_entities/BE0000781TargetHumansRegulates the frequency of neuronal action potential firing in response to mechanical stimuli, and plays a role in the perception of pain caused by mechanical stimuli, but does not play a role in the perception … In contrast, a heterotetrameric channel formed by KCNA1 and KCNA4 shows rapid inactivation (PubMed:17156368).
Polypeptides: Potassium voltage-gated channel subfamily A member 1HLA class I histocompatibility antigen, A alpha chain
go.drugbank.com/bio_entities/BE0003483TargetHumansIn complex with B2M/beta 2 microglobulin displays primarily viral and tumor-derived peptides on antigen-presenting cells for recognition by alpha-beta T cell receptor (TCR) on HLA-A-restricted CD8-positive
Polypeptides: HLA class I histocompatibility antigen, A alpha chainSynonyms: HLA-A, MHC class I antigen A*3Potassium voltage-gated channel subfamily A member 7
go.drugbank.com/bio_entities/BE0004719TargetHumansAssuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with
Polypeptides: Potassium voltage-gated channel subfamily A member 7C-type lectin domain family 14 member A
go.drugbank.com/bio_entities/BE0005467TargetHumansPolypeptides: C-type lectin domain family 14 member ANuclear receptor subfamily 4 group A member 3
go.drugbank.com/bio_entities/BE0008998TargetHumansDuring inner ear, plays a role as a key mediator of the proliferative growth phase of semicircular canal development (By similarity). … Also plays a role in metabolism; by modulating feeding behavior; and by playing a role in energy balance by inhibiting the glucocorticoid-induced orexigenic neuropeptides AGRP expression, at least in part
Polypeptides: Nuclear receptor subfamily 4 group A member 3Leukocyte immunoglobulin-like receptor subfamily A member 4
go.drugbank.com/bio_entities/BE0013620TargetHumansproduction of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as a … Activates a signaling cascade in complex with FCER1G that results in phosphorylation of Src family and Syk kinases and thereby triggers mobilization of intracellular Ca(2+) (PubMed:16735691, PubMed:19564354
Polypeptides: Leukocyte immunoglobulin-like receptor subfamily A member 4