Potassium voltage-gated channel subfamily A member 1

BE0000781ProteinHumansKCNA1

Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and the central nervous system, but also in the kidney (PubMed:19903818, PubMed:8845167). It is acted on by 7 drugs in DrugBank.

Gene name
KCNA1
UniProtKB entry
Q09470Swiss-Prot
Cellular location
Cell membrane
Residues / weight
495 residues · 56,465 Da
Also known as
Voltage-gated K(+) channel HuKI · Voltage-gated potassium channel HBK1 · Voltage-gated potassium channel subunit Kv1.1

Resolves to

Protein
UniProtQ09470UniProt nameKCNA1_HUMAN
Gene
HGNCHGNC:6218NCBI Gene3736GenBank186663GeneCardsKCNA1
Pharmacology
IUPHAR/GtoPdb538KEGGhsa:3736
Drugs

What you can answer from here — as of September 07, 2019

7DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
31GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
40+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Potassium voltage-gated channel subfamily A member 1, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In