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Crisaborole
go.drugbank.com/drugs/DB05219ApprovedInvestigationalCrisaborole is a novel oxaborole approved by FDA on December 14, 2016 as Eucrisa, a topical treatment of for mild to moderate atopic dermatitis. … This non-steroidal agent is efficacious in improving disease severity, reducing the risk of infection and reducing the signs and symptoms in patients 2 years old and older.
Categories: Agents for Dermatitis, Excluding CorticosteroidsChronic Myelogenous Leukemia (CML)
go.drugbank.com/conditions/DBCOND0040386Synonyms: Chronic myelogenous leukemia, no International Classification of Diseases for Oncology subtypeLonafarnib
go.drugbank.com/drugs/DB06448ApprovedInvestigational[L23414, L23544] Lonafarnib was granted FDA approval on November 20, 2020, and is the first FDA-approved treatment for HGPS and other related progeroid laminopathies.[L23414, L23549] … A224379, A224394] Lonafarnib is a farnesyl transferase (FTase) inhibitor (FTI), which reduces the farnesylation of numerous cellular proteins, including progerin; as progerin farnesylation is important for
Magnesium hydroxide
go.drugbank.com/drugs/DB09104ApprovedInvestigationalIt can also be used topically as a deodorant or for the relief of canker sores (aphthous ulcers). … Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form.
Mixtures: UFOR, UFORCategories: Drugs for Acid Related DisordersFish oil
go.drugbank.com/drugs/DB13961ApprovedInvestigationalNutraceuticalIt is indicated in adults as a source of calories and essential fatty acids for parenteral nutrition when oral or enteral nutrition is not possible, insufficient, or contraindicated. … Regardless, the specific mechanisms of action for these effects have yet to be formally elucidated.
Mixtures: SmofKabiven Emulsion for Infusion, SmofKabiven Emulsion for InfusionFerumoxytol
go.drugbank.com/drugs/DB06215ApprovedInvestigational[L54501] The drug remains approved in the US, with a new indication being approved in October of 2025 for Ferumoxytol's use as a diagnostic agent for MRI of the brain. … Ferumoxytol is an intravenously administered iron preparation previously indicated in the EU and the US for the treatment of iron deficiency anemia in adult patients with chronic kidney disease (CKD) [
Categories: Compounds used in a research, industrial, or household settingNavepegritide
go.drugbank.com/drugs/DB17824ApprovedInvestigational[L56065] Navepegritide was approved by the US FDA in February 2026 for use in patients 2 years of age and older with achondroplasia with open epiphyses.[L56058,L56065] … antagonizes the overactive fibroblast growth factor receptor 3 (FGFR3) signaling pathway responsible for impaired bone growth in individuals with achondroplasia.
Bisoctrizole
go.drugbank.com/drugs/DB11262ApprovedBisoctrizole, or methylene bis-benzotriazolyl tetramethylbutylphenol, is a broad-spectrum organic UV filter that is marketed as Tinosorb M [A19212]. … It is a benzotriazole-based organic compound that absorbs, reflects, and scatters both UV-A and UV-B rays.
Polyethylene glycol 400
go.drugbank.com/drugs/DB11077ApprovedInvestigationalPEGylation occurs when PEGs are attached to numerous protein medications, allowing for greater solubility for selected drugs. … It is used in ophthalmic solutions for the relief of burning, irritation and/or discomfort that follows dryness of the eye [L1785].
Mixtures: Visine for Red Eye Cool, Visine for Red Eye WorkplaceCategories: Compounds used in a research, industrial, or household settingMepivacaine
go.drugbank.com/drugs/DB00961ApprovedInvestigationalVet approvedIt is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route.