Chronic Myelogenous Leukemia (CML) (DBCOND0040386)

Identifiers

Synonyms
Chronic Leukemia Myelogenous / Chronic Myelogenous Leukaemia / Chronic Myelogenous Leukemia / Chronic Chronic Myelogenous Leukemia / Chronic myeloid leukaemia / Leukemia myelocytic chronic / Leukaemia myelocytic chronic / Chronic granulocytic leukaemia / Myeloid leukemia, chronic / Chronic granulocytic leukemia / Myeloid leukaemia, chronic / CML / Chronic myelocytic leukaemia / Chronic myelocytic leukemia / Chronic myeloid leukemia / Leukaemias chronic myeloid / Chronic myeloid leukemia, BCR/ABL-positive / Chronic myeloid leukemia (disorder) / Chronic myeloid leukemia (morphologic abnormality) / Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Busulfan
An alkylating agent used to treat chronic myelogenous leukemia.
Hydroxyurea
An antimetabolite used to treat sickle cell anemia crisis, resistant chronic myeloid leukemia, and Locally advanced squamous cell carcinomas of the head and neck (excluding the lip).
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06297161
A Study to Learn About the Study Medicine Bosulif in Adult Patients With Chronic Myeloid Leukemia(CML).Not AvailableNot Availablenot_yet_recruiting
NCT03205267
Phase II Study Testing the Tolerability and the Efficacy of Bosutinib in Chronic Phase CML Patientstreatment2unknown_status
NCT02730299
Stem Cell Transplantation With NiCord® (Omidubicel) vs Standard UCB in Patients With Leukemia, Lymphoma, and MDStreatment3active_not_recruiting
NCT01720264
Multicenter Phase II of CD26 Using Sitagliptin for Engraftment After UBC Transplanttreatment2completed
NCT00179764
Immunoablative Mini Transplant (Hematopoietic Peripheral Blood Stem Cell Transplant [HPBSC])No drug interventionstreatmentNot Availablecompleted
NCT02736721
Expanded Access Study With Peginterferon Alfa-2a (Pegasys) in Participants With Chronic Myelogenous Leukemia (CML)treatment3completed
NCT02231853
Phase I/II Trial of Early Infusion of Rapidly-generated Multivirus Specific T Cells (MVST) to Prevent Post Transplant Viral InfectionsNo drug interventionsprevention1terminated
NCT01768845
Unrelated Umbilical Cord Blood (UBC)TransplantationNo drug interventionstreatmentNot Availablecompleted
NCT01351545
A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)No drug interventionsNot AvailableNot Availablerecruiting
NCT00471497
A Study of Imatinib Versus Nilotinib in Adult Patients With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Chronic Myelogenous Leukemia in Chronic Phase (CML-CP)treatment3completed
NCT01885897
IL-15 Super Agonist ALT-803 to Treat Relapse Of Hematologic Malignancy After Allogeneic SCTtreatment1 / 2completed
NCT00111683
MK0457 in Patients With Leukemia (0457-003)No drug interventionstreatment1completed
NCT03128411
Study of Bosutinib in Japanese Adult Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemiatreatment2completed
NCT02117115
Abdominal CT to Predict the Risk of Acute Graft-versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantationscreening0completed
NCT04808115
IIT PH1 KDS-1001 in Patients With CMLNo drug interventionstreatment1not_yet_recruiting
NCT00672152
A Phase I Study of WT1 Peptides to Induce Anti-Leukemia Immune Responses Following TransplantationNo drug interventionstreatment1terminated
NCT01758042
Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood DisordersNo drug interventionstreatmentNot Availablerecruiting
NCT00241358
Study Evaluating AMD3100 for Transplantation of Sibling Donor Stem Cells in Patients With Hematological Malignanciestreatment1 / 2completed
NCT01517035
Improving Blood Stem Cell Collection and Transplant ProceduresNo drug interventionstreatment1 / 2completed
NCT03885830
Precision Dosing of Tyrosine Kinase Inhibitors in CML PatientsNot AvailableNot Availablecompleted
NCT02259348
Repeat Transplantation for Relapsed or Refractory Hematologic Malignancies Following Prior Transplantationtreatment2terminated
NCT01663766
Phase I Study of Milatuzumab for Graft Versus Host Diseasetreatment1terminated
NCT02200380
A Safety and Tolerability Study of CDX-301 With or Without Plerixafor for Stem Cell Mobilization in Matched Related Allogeneic Donor/Recipient Sibling Transplant Pairstreatment2terminated
NCT01735955
Study to Allow Access to Nilotinib for Patients Who Are on Nilotinib Treatment in a Novartis-sponsored Studytreatment4completed
NCT01050764
Haploidentical Allogeneic Transplant With Post-transplant Infusion of Regulatory T-cellstreatment1 / 2terminated
NCT01503502
A Phase II Study of Flumatinib Versus Imatinib to Treat Philadelphia Chromosome Positive Chronic Myelogenous Leukemiatreatment2unknown_status
NCT00619879
Myeloablative Hematopoietic Progenitor Cell Transplantation (HPCT) for Pediatric MalignanciesNo drug interventionstreatment3unknown_status
NCT00569179
A Phase I Trial of Alloreactive Cell Infusion Following Transplantation of Haplotype Cells in Patients With Myeloid MalignanciesNo drug interventionstreatment1terminated
NCT05884333
Cord Blood Transplant in Adults With Blood CancersNo drug interventionstreatment2recruiting
NCT00038597
Phase II Study of SCH66336, A Farnesyltransferase Inhibitor in Chronic Myelogenous Leukemia (CML)treatment2completed
NCT00467961
Stem Cell Transplantation for Patients With Cancers of the BloodNo drug interventionstreatment2completed
NCT02226861
Ultra-Low Dose IL-2 Therapy as GVHD Prophylaxis in Haploidentical Allogeneic Stem Cell Transplantationprevention1completed
NCT02161978
Vascular Dysfunction and Antiangiogenic TherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT00862719
Sitagliptin Umbilical Cord Blood Transplant Studytreatment2completed
NCT03959241
TAC/MTX vs. TAC/MMF/PTCY for Prevention of Graft-versus-Host Disease and Microbiome and Immune Reconstitution Study (BMT CTN 1703/1801)prevention3completed
NCT05092048
A Study for PRO of CML in Real WordNo drug interventionsNot AvailableNot Availableunknown_status
NCT03421626
Clinical Evaluation of a Test for Monitoring Patients Diagnosed With Chronic Myeloid Leukemia (CML)No drug interventionsNot AvailableNot Availablecompleted
NCT04795427
Study of Efficacy and Safety of CML-CP Patients Treated With Asciminib Versus Best Available Therapy, Previously Treated With 2 or More Tyrosine Kinase Inhibitorstreatment2active_not_recruiting
NCT01243489
Compliance: Role Emerges for Success in Chronic Myelogenous Leukaemia (CML): Evaluation aND OptimisationNo drug interventionsother4completed
NCT04518644
Nilotinib, for Patients With CML-CP or CML-APNot AvailableNot Availableno_longer_available
NCT00129740
Phase II Nilotinib With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia (CML)treatment2completed
NCT05640804
A Bioequivalence Study of Dasatinib Tablettreatment1completed
NCT01413568
Safety and Efficacy of POL6326 for Mobilization/Transplant of Sibling Donor in Patients With Hematologic MalignanciesNo drug interventionstreatment1 / 2completed
NCT00923910
Wilm's Tumor 1 Protein Vaccine to Treat Cancers of the Bloodtreatment1 / 2completed
NCT00185523
Allogeneic Transplantation for Patients With Acute Leukemia or Chronic Myelogenous Leukemia (CML)No drug interventionsNot AvailableNot Availableterminated
NCT00718263
Efficacy and Safety of Nilotinib Patients With Newly Diagnosed CML - CP (Chronic Myelogenous Leukemia - Chronic Phase)treatment3active_not_recruiting
NCT01784068
Nilotinib Treatment-free Remission Study in CML (Chronic Myeloid Leukemia) Patientsother2active_not_recruiting
NCT04877522
Asciminib Roll-over Studytreatment4recruiting
NCT06131801
Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a SolutionNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00159003
Analysis of Genetic Factors Related to Predisposition and Prognosis of Hematological Malignancies in IsraelNo drug interventionsNot AvailableNot Availablecompleted
NCT00041990
Phase II Trial of Decitabine in Patients With Chronic Myelogenous Leukemia Accelerated Phase Who Are Refractory to Imatinib Mesylate (Gleevec)treatment2completed
NCT06301321
The Evaluation and Comparison of BCR-ABL p210 mRNA Transcripts (%IS Unit) Results Between Dr. PCR™ BCR-ABL1 Major IS Detection Kit (Optolane) and QXDx™ BCR-ABL %IS Kit (Bio-Rad) in Chronic Myeloid Leukemia PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT00047502
Study of Lonafarnib and Gleevec in Chronic Myelogenous Leukemiatreatment1completed
NCT01390402
Alloreactive Haploidentical Natural Killer (NK) Cells With Busulfan and Fludarabine/ATGtreatment2completed
NCT03106779
Study of Efficacy of CML-CP Patients Treated With ABL001 Versus Bosutinib, Previously Treated With 2 or More TKIstreatment3active_not_recruiting
NCT01338987
Pilot Study of Leuprolide to Improve Immune Function After Allogeneic Bone Marrow Transplantationtreatment2completed
NCT04191187
Reduced Intensity Flu/Mel/TBI Conditioning for HAPLO HCT Patients With Hematologic Malignanciestreatment2active_not_recruiting
NCT00990587
Study Evaluating the Tolerance and Biologic Activity of Oral Ciclopirox Olamine in Patients With Relapsed or Refractory Hematologic Malignancytreatment1completed
NCT00144677
Sirolimus With Tacrolimus for Graft-vs-Host Disease Prophylaxis After Un-Related Stem Cell Transplantationprevention2completed
NCT00760877
Nilotinib Versus Standard Imatinib (400/600 mg Every Day (QD)) Comparing the Kinetics of Complete Molecular Response for Chronic Myelogenous Leukemia in Chronic Phase (CML-CP) Pts With Evidence of Persistent Leukemia by Real-time Quantitative Polymerase Chain Reaction (RQ-PCR)treatment3completed
NCT00807677
A Phase 1 Dose Escalation Study of TAK-901 in Subjects With Advanced Hematologic Malignanciestreatment1completed
NCT00101647
Study of Dasatinib (BMS-354825) in Patients With Accelerated Phase Chronic Myeloid Leukemiatreatment2completed
NCT01011998
A Study of Imatinib and Valproic Acid in Patients With Chronic Myelogenous Leukemia (CML)treatment2withdrawn
NCT01611298
Donor-Derived Humoral Immunity, Hematopoietic Stem Cell Transplantation, TARpreventionNot Availablecompleted
NCT05805605
Allo HSCT Using RIC and PTCy for Hematological Diseasestreatment2recruiting
NCT02765997
StemRegenin-1 Expanded vs Unexpanded UCB for High Risk Heme MalignanciesNo drug interventionstreatment2withdrawn
NCT02709083
Dasatinib or Nilotinib Followed by Imatinib in Patients With Newly Diagnosed, Chronic Phase Chronic Myeloid Leukemiatreatment2terminated
NCT01500161
Pooled Unrelated Donor Umbilical Cord Blood Transplant For Hematologic Malignancy Needing Allogeneic Stem Cell Transplant Without Related HLA-Matchtreatment2terminated
NCT00579111
Reduced Intensity Preparative Regimen Followed by Stem Cell Transplant (FAB)treatment1 / 2terminated
NCT02181478
Intra-Osseous Co-Transplant of UCB and hMSCtreatment0completed
NCT02081378
A Phase I Study of Oral Asciminib (ABL001) in Patients With CML or Ph+ ALLtreatment1completed
NCT06088888
TGRX-678 US Phase I for Subjects With Refractory or Advanced Chronic Myelogenous LeukemiaNo drug interventionstreatment1recruiting
NCT01130688
Safety of Zileuton (Zyflo) in Combination With Imatinib Mesylate (Gleevec) in CML.treatment1terminated
NCT00109707
A Study of Oral AMN107 in Adults With Chronic Myelogenous Leukemia (CML) or Other Hematologic Malignanciestreatment1 / 2completed
NCT00852709
Phase I Dose-Escalation Trial of Clofarabine Followed by Escalating Doses of Fractionated Cyclophosphamide in Children With Relapsed or Refractory Acute Leukemiastreatment1terminated
NCT05088356
Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Grafttreatment1recruiting
NCT01149915
Study of Hypoxia-Activated Prodrug TH-302 to Treat Advanced Leukemiastreatment1completed
NCT01484015
Prolonged or Standard Infusion of Cefepime Hydrochloride in Treating Patients With Febrile Neutropeniatreatment1completed
NCT00346632
An Ascending Dose Study of KW-2449 in Acute Leukemias, Myelodysplastic Syndromes, and Chronic Myelogenous LeukemiaNo drug interventionstreatment1terminated
NCT00975975
Basiliximab #2: In-Vivo Activated T-Cell Depletion to Prevent Graft-Versus_Host Disease (GVHD) After Nonmyeloablative Allotransplantation for the Treatment of Blood Cancertreatment2completed
NCT00038870
Therapy of Relapsed AML With Chemotherapy and Dendritic Cell Activated LymphocytesNo drug interventionstreatmentNot Availablewithdrawn
NCT00811070
Study Evaluating SKI-606 (Bosutinib) In Japanese Subjects With Philadelphia Chromosome Positive Leukemiastreatment2completed
NCT00309842
Myeloablative Umbilical Cord Blood Transplantation in Hematological Diseasestreatment2completed
NCT00723099
Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancertreatment2completed
NCT00171899
Study Comparing Standard Dose and High-dose Imatinib Mesylate in Patients With Chronic Phase Philadelphia Chromosome Positive (Ph+) Chronic Myelogenous Leukemia (CML)treatment4completed
NCT00500006
A Phase I Dose Escalation Combination Study in Patients With Chronic Myelogenous Leukemia (CML) and Philadelphia Chromosome-Positive (Ph+) Acute Lymphoblastic Leukemia (ALL)(0457-009)(TERMINATED)treatment1terminated
NCT02047149
Evaluating the Safety of Zileuton (Zyflo®) in Combination With Dasatinib (Sprycel®) in Chronic Myelogenous Leukemiatreatment1terminated
NCT00719836
A Phase 1/2 Study of SB1518 for the Treatment of Advanced Myeloid Malignanciestreatment1 / 2completed
NCT00079313
Imatinib (Gleevec(Registered Trademark)) to Treat Chronic Myelomonocytic Leukemia and Atypical Chronic Myelogenous Leukemiatreatment2completed
NCT00038818
CD8 DLI for Patients With Relapse or Residual Disease Following Allogeneic Stem Cell TransplantationNo drug interventionstreatmentNot Availableterminated
NCT01030718
Rollover Study of BMS-354825 in Patients With CML and Ph+ALLtreatment1 / 2completed
NCT00980018
An Exploratory Trial to Assess the Improvement of Adverse Events in Chronic Myelogenous Leukemia Patients Treated With Imatinib When Switched to Nilotinib Treatmenttreatment4completed
NCT04888741
Methods of T Cell Depletion Trial (MoTD)prevention2recruiting
NCT00954941
Ondansetron Versus Aprepitant Plus Ondansetron for Emesistreatment2completed
NCT00802841
Randomized Phase Lll Study of Imatinib Dose Optimization vs Nilotinib in CML Patients With Suboptimal Response to Imatinibtreatment3completed
NCT01272817
Nonmyeloablative Allogeneic TransplantNo drug interventionstreatmentNot Availablecompleted
NCT01634217
Inducible Regulatory T Cells (iTregs) in Non-Myeloablative Sibling Donor Peripheral Blood Stem Cell TransplantationNo drug interventionstreatment1completed
NCT01397734
Arsenic Trioxide and Tyrosine Kinase Inhibitors for Chronic Myelogenous Leukemia (CML)treatment1terminated
NCT00378534
Methods to Enhance the Safety and Effectiveness of Stem Cell Transplantstreatment2completed
NCT02661035
Allo HSCT Using RIC for Hematological Diseasestreatment2completed
NCT01364363
Unrelated Donor Stem Cell TransplantationNo drug interventionstreatmentNot Availablecompleted
NCT01890486
The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative RegimenNo drug interventionsNot AvailableNot Availablerecruiting
NCT02145039
Reduced Intensity Conditioning and Haploidentical Related Bone Marrow for Patients With Hematologic DiseasestreatmentNot Availableterminated
NCT00514722
Pilot Study of Umbilical Cord Blood Transplantation in Adult Patient With Advanced Hematopoietic MalignanciesNo drug interventionstreatmentNot Availableterminated
NCT01755325
Phase III Study of Compound Formula Realgar-Indigo Naturalis Plus Imatinib Versus Placebo Plus Imatinib in Adult CML-CP Patients With Ph+treatment3suspended
NCT00626626
Clofarabine and Non-Myeloablative Allogeneic Hematopoietic Transplantationtreatment1 / 2terminated
NCT04282174
CD34+ Enriched Transplants From HLA-Compatible Patients With Hematologic Malignanciestreatment2withdrawn
NCT03314974
Myeloablative Allo HSCT With Related or Unrelated Donor for Heme DisordersNo drug interventionstreatment2recruiting
NCT00088231
PTK 787 and Gleevec in Patients With AML, AMM, and CML-BPtreatment1 / 2completed
NCT01110473
ABT-348 as Monotherapy and in Combination With Azacitidine to Treat Advanced Hematologic Malignanciestreatment1completed
NCT01207076
AHN-12 Biodistribution in Advanced LeukemiaNo drug interventionstreatment1terminated
NCT00661180
Open Label Phase II Study of BAY 43-9006 in Chronic Myelogenous Leukemia (CML) Patients Resistant to Gleevectreatment2completed
NCT00709592
Reduced Intensity Total Body Irradiation + Thymoglobulin Followed by Allogeneic PBSCTtreatment2completed
NCT02511340
A Phase II Study to Evaluate the Efficacy and the Safety of Flumatinib in CML-AP or CML-BP Patientstreatment2unknown_status
NCT03578367
Study of Efficacy and Safety of Asciminib in Combination With Imatinib in Patients With Chronic Myeloid Leukemia in Chronic Phase (CML-CP)treatment2active_not_recruiting
NCT02722668
UCB Transplant for Hematological Diseases Using a Non Myeloablative Preptreatment2active_not_recruiting
NCT02146846
Population Pharmacokinetics of Imatinib in CML Patients in IranNot AvailableNot Availableterminated
NCT00866346
PR1-Specific Cytotoxic T-Lymphocyte Infusion With Recurrent Chronic Myelogenous Leukemia (CML) After Allogeneic Hematopoietic TransplantationNo drug interventionstreatment1withdrawn
NCT01366612
PRO#1278: Fludarabine and Busulfan vs. Fludarabine, Busulfan and Total Body Irradiationtreatment3terminated
NCT00493181
Interleukin 11, Thrombocytopenia, Imatinib in Chronic Myelogenous Leukemia (CML) Patientstreatment2completed
NCT00270881
Safety and Efficacy of Unrelated Cord Blood Transplantation for Adult Patients With Hematologic Malignanciestreatment1 / 2completed
NCT00368355
T Cell Depletion for Recipients of HLA Haploidentical Related Donor Stem Cell Graftstreatment2completed
NCT00594308
In-Vivo Activated T-Cell Depletion to Prevent GVHDtreatmentNot Availableterminated
NCT01513603
Trial of Cladribine, Cytarabine, Mitoxantrone, Filgrastim (CLAG-M) in Relapsed Acute Lymphoblastic Leukemiatreatment2unknown_status
NCT00042003
Phase II Trial of Decitabine in Patients With Chronic Myelogenous Leukemia Blast Phase Who Are Refractory to Imatinib Mesylate (Gleevec)treatment2completed
NCT01494103
Administration of Donor T Cells With the Caspase-9 Suicide Genetreatment1active_not_recruiting
NCT04014764
Collect and Assess Tissue Samples From Subjects With Hematologic MalignancyNo drug interventionsNot AvailableNot Availablecompleted
NCT02338479
Natural History and Biology of Long-Term Late Effects Following Hematopoietic Cell Transplant for Childhood Hematologic MalignanciesNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00674479
INCB018424 in Patients With Advanced Hematologic Malignanciestreatment2completed
NCT04948333
Asciminib Treatment Optimization in ≥ 3rd Line CML-CP.treatment3active_not_recruiting
NCT00098033
Investigation of Clofarabine in Acute Leukemiastreatment2completed
NCT01003054
Autologous Transplantation for Chronic Myelogenous Leukemiatreatment2completed
NCT03547154
Polyethylene Glycol Interferon Alfa-2b (PEG Intron) Versus Interferon Alfa-2b (INTRON^® A) in the Treatment of Newly Diagnosed Chronic Myelogenous Leukemia (CML) (C98026)treatment2 / 3terminated
NCT00337454
Study of BMS-354825 in Subjects With CML Who Are Resistant to or Intolerant of Imatinib or Ph+All in Japantreatment1 / 2completed
NCT01274351
Study of Nilotinib as First Line Treatment in Philadelphia Chromosome Positive(Ph+) Chronic Myelogenous Leukemia in Chronic Phase (CML-CP)treatment2completed
NCT02743351
Study of ProTmune for Allogeneic HCT in Adult Patients With Hematologic MalignanciesNo drug interventionsprevention1 / 2completed
NCT02592447
Cognitive Behavioral Intervention for Targeted Therapy Fatigue (CBT-TTF) InterventionNo drug interventionssupportive_careNot Availablecompleted
NCT01499147
Fludarabine Based Conditioning for Allogeneic Transplantation for Advanced Hematologic MalignanciestreatmentNot Availablecompleted
NCT02991898
Adoptive TReg Cell for Suppression of aGVHD After UCB HSCT for Heme MalignanciesNo drug interventionstreatment2terminated
NCT01696461
A Phase II Study Evaluating the Safety and Efficacy of Subcutaneous Plerixafortreatment2completed
NCT00384228
A Phase l/ll Study of AMN107 in Adult Patients With Glivec-intolerant CML or Relapsed-refractory Ph+ALLtreatment1 / 2completed
NCT01326728
Relapsed Malignant Blood Cancer After Allogeneic Hematopoietic Stem Cell TransplantationNo drug interventionsNot AvailableNot Availableterminated
NCT03674411
Trial Evaluating MGTA-456 in Patients With High-Risk Malignancytreatment2active_not_recruiting
NCT00697671
Pilot Study of Haploidentical Natural Killer Cell Infusions for Poor Prognosis Non-AML Hematologic Malignanciestreatment1completed
NCT03625388
Low Dose Dasatinib (50 mg Daily) as First-line Treatment for Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemiatreatment2completed
NCT04904588
HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamidetreatment2recruiting
NCT01660607
Phase 1-2 MAHCT w/ TCell Depleted Graft w/ Simultaneous Infusion Conventional and Regulatory T CellNo drug interventionstreatment1 / 2completed
NCT02581007
Reduced Intensity Conditioning Transplant Using Haploidentical Donorstreatment2completed
NCT01036009
A Study of Withdrawal of Immunosuppression and Donor Lymphocyte Infusions Following Allogeneic Transplant for Pediatric Hematologic MalignanciesNo drug interventionstreatment2completed
NCT00415909
TALL-104 and Gleevec in Chronic Myelogenous Leukemia Patientstreatment2terminated
NCT01951885
Tac, Mini-MTX, MMF Versus Tac, MTX for GVHD Preventionsupportive_care3completed
NCT02208037
Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203)prevention2completed
NCT00285259
Cytomegalovirus (CMV) Vaccine in Donors and Recipients Undergoing Allogeneic Hematopoietic Cell Transplant (HCT)No drug interventionstreatment2completed
NCT02639559
Safety and Efficacy of BL-8040 for the Mobilization of Donor Hematopoietic Stem Cells and Allogeneic Transplantation in Patients With Advanced Hematological Malignanciestreatment2completed
NCT02829775
A Study of Continued Treatment Among Participants Who Have Responded to Peginterferon Alfa-2a (Pegasys®) or Recombinant Interferon Alfa-2a (Roferon-A®) in Prior Clinical Studiestreatment2 / 3completed
NCT01020175
Peripheral Blood (PB) Versus Bone Marrow (BM) in Allogeneic Stem Cell TransplantationNo drug interventionstreatment3completed
NCT00413270
Oral Nilotinib in Adults With Chronic Myeloid Leukemia (CML) in Blast Crisis Who Are Imatinib Resistant or IntolerantNot AvailableNot Availableno_longer_available
NCT03216070
Low-dose Dasatinib as First-line Treatment for Chronic Myeloid Leukemiatreatment4unknown_status
NCT00569842
Investigation of the Cylex® ImmuKnow® AssayNo drug interventionsNot AvailableNot Availablecompleted
NCT01962636
Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological DiseasestreatmentNot Availablerecruiting
NCT00513318
Pilot Study of Reduced-Intensity Umbilical Cord Blood Transplantation in Adult Patients Wtih Advanced Hematopoietic MalignanciesNo drug interventionsNot AvailableNot Availableterminated
NCT01294618
Nilotinib + Pegylated Interferon Alpha 2a for Untreated Chronic Phase Chronic Myelogenous Leukemiatreatment2completed
NCT00739141
Conditioning Regimen and the Transplantation of Unrelated Donor Umbilical Cord Blood in Patients With Hematologic Malignancies.treatment2completed
NCT01452334
Safety Study of Anti-Programmed Death-Ligand 1 in Hematologic MalignancyNo drug interventionstreatment1withdrawn
NCT00042016
Phase II Trial of Decitabine in Patients With Chronic Myelogenous Leukemia Chronic Phase Who Are Refractory to Imatinib Mesylate (Gleevec)treatment2completed
NCT00089596
Infusion of Specially Treated Umbilical Cord Stem Cells After Chemoradiation Treatment for Blood CancersNo drug interventionstreatment1 / 2completed
NCT00967525
Intraosseous Infusion of Unrelated Cord Blood GraftsNo drug interventionstreatmentNot Availableterminated
NCT01075425
Belinostat and Bortezomib in Treating Patients With Relapsed or Refractory Acute Leukemia or Myelodysplastic Syndrometreatment1completed
NCT02501330
Safety And Efficacy Of BosutinibNot AvailableNot Availablecompleted
NCT00081926
Gleevec Trial in Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemiatreatment4completed
NCT01901666
Assessment Of Gh-Igf-1 Axis In Children With Chronic Myelogenous Leukemia (CML) In Remissiondiagnostic4unknown_status
NCT00334074
Clofarabine and Ara-C for the Treatment of Relapsed AML and Untreated MDStreatment2completed
NCT01690520
Donor Umbilical Cord Blood Transplant With or Without Ex-vivo Expanded Cord Blood Progenitor Cells in Treating Patients With Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, or Myelodysplastic Syndromestreatment2completed
NCT00660920
Safety Study of AP24534 to Treat Chronic Myelogenous Leukemia (CML) and Other Hematological Malignanciestreatment1completed
NCT02996773
Haploidentical BMT With Post-Transplant Cyclophosphamide and Bendamustinetreatment1active_not_recruiting
NCT01279473
Study to Evaluate Nilotinib in Adult Patients With Imatinib-resistant or Imatinib-intolerant Chronic Myelogenous Leukemia (CML), or Relapse/Refractory Ph+ Acute Lymphoblastic Leukemia (ALL) (Extension Study)treatment1 / 2completed
NCT00674427
Trial of Donor Lymphocyte Infusion (DLI) and Activated DLI Following Relapse After Allogeneic Stem Cell TransplantNo drug interventionstreatment1terminated
NCT00412360
Single vs Double Umbilical Cord Blood Transplants in Children With High Risk Leukemia and Myelodysplasia (BMT CTN 0501)treatment3completed
NCT00571662
Safety and Efficacy of Pentostatin and Low Dose TBI With Allogenic Peripheral Blood Stem Cell Transplanttreatment2completed
NCT00333840
Safety and Efficacy of Imatinib Versus Interferon-α Plus Cytarabine in Patients With Newly Diagnosed Philadelphia Chromosome Positive Chronic Myelogenous Leukemiatreatment3completed
NCT00683046
T-Cell Depleted Allogeneic Stem Cell Transplantation for Patients With Hematologic Malignanciestreatment2completed
NCT05434312
TGRX-678 Chinese Phase I in Chronic Myelogenous Leukemia (CML) PatientsNo drug interventionstreatment1recruiting
NCT06530810
Study of HS-10382 Combination in Patients With Chronic Myeloid Leukemia (CML)treatment1not_yet_recruiting
NCT01474681
Safety and Tolerability of HSC835 in Patients With Hematological Malignanciestreatment1 / 2completed
NCT00580281
Effect of Imatinib on Bone Metabolism in Patients With Chronic Myelogenous Leukemia or Gastrointestinal Stromal TumorsNo drug interventionsdiagnosticNot Availablecompleted
NCT00539695
Low Dose IL-2, Hematopoietic Stem Cell Transplantation, IL2 for GVHDtreatment2completed
NCT02566395
Stem Cell Transplantation From HLA Partially-Matched Related Donors for Patients With Hematologic Malignanciestreatment3completed
NCT00816114
Chart Review Study of Chronic Myelogenous Leukemia (CML) Patients Treated With Imatinib Outside of a Clinical TrialNo drug interventionsNot AvailableNot Availablerecruiting
NCT01316250
Gleevec as Maintenance Therapy After Cytogenetic Response With Nilotinib in Newly Diagnosed Chronic Myelogenous LeukemiatreatmentNot Availablerecruiting
NCT02593123
Adoptive Immunotherapy in Relapsed Hematological Malignancy: Early GVHD Prophylaxistreatment2completed
NCT01368523
Study of Oral AMN107 (Nilotinib) in Adult Patients With Imatinib - Resistant or - Intolerant Chronic Myeloid Leukemia in Blast Crisis, Accelerated Phase or Chronic Phase Previously Enrolled to CAMN107A2109 Trialtreatment4completed
NCT00003838
Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrowtreatment2completed