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Zalcitabine
go.drugbank.com/drugs/DB00943ApprovedWithdrawnThe compound is a potent inhibitor of HIV replication at low concentrations, acting as a chain-terminator of viral DNA by binding to reverse transcriptase. … This modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the elongation of DNA chains, thus resulting in the termination of viral DNA growth.
Gemifloxacin
go.drugbank.com/drugs/DB01155ApprovedInvestigationalGemifloxacin acts by inhibiting DNA synthesis through the inhibition of both DNA gyrase and topoisomerase IV, which are essential for bacterial growth. … Gemifloxacin is a quinolone antibacterial agent with a broad-spectrum activity that is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia.
Erdafitinib
go.drugbank.com/drugs/DB12147ApprovedInvestigationaltool kit to treat such a prevalent medical condition. … [L5956, L5959] At the same time, the FDA also approved the therascreen FGFR RGQ RT-PCR Kit (Qiagen) for utilization as a companion diagnostic with erdafitinib for selecting patients for the indicated therapy
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic IndexBisoctrizole
go.drugbank.com/drugs/DB11262ApprovedBisoctrizole is not approved by the FDA, but is approved in the EU and other parts of the world as a UV-filter in sunscreens, day care products and skin lightening products at a maximum concentration of … It is a benzotriazole-based organic compound that absorbs, reflects, and scatters both UV-A and UV-B rays.
Mestranol
go.drugbank.com/drugs/DB01357ApprovedWithdrawnThe 3-methyl ether of ethinyl estradiol. It must be demethylated to be biologically active. It is used as the estrogen component of many combination ORAL contraceptives.
Mixtures: Norinyl 1/50 -(21-day Regimen), Norinyl 1/50 -(28-day Regimen)Talniflumate
go.drugbank.com/drugs/DB09295InvestigationalTalniflumate has been approved for approximately 20 years in Argentina other countries (excluding the United States, Europe, and Japan) [L1405]. … Talniflumate, is an anti-inflammatory molecule studied and used as a mucin regulator in the treatment of cystic fibrosis, chronic obstructive pulmonary disease (COPD) and asthma [L1400].
Lazertinib
go.drugbank.com/drugs/DB16216ApprovedInvestigational[A264289] It was approved by the FDA on August 19, 2024.[L51189] Lazertinib is used alone or in combination with other chemotherapeutic agents.[L51184]
Copper oxodotreotide Cu-64
go.drugbank.com/drugs/DB15873Approved[A220348] Copper Cu 64 dotatate has a longer half-life and can be produced once a day as opposed to several times a day, and lower positron energy lending to improved spatial resolution. … Copper Cu 64 dotatate is a newly approved Cu labeled somatostatin analog and has several advantages over <sup>68</sup>Ga-labeled somatostatin analogs for positron emission tomography (PET).
Schizochytrium DHA oil
go.drugbank.com/drugs/DB11069ApprovedSynonyms: Schizochytrium DHA oil, DHA from algal (schizochytrium) oilMixtures: PreferaOB plus DHA, Levomefolate Calcium and Schizochytrium DHAGrapiprant
go.drugbank.com/drugs/DB12836InvestigationalVet approved[L4766] Grapiprant has been approved in March 2016 by the FDA's Center for Veterinary Medicine as a non-cyclooxygenase inhibiting NSAID for veterinary use.[A39836] … Grapiprant, also known as AT-001 and CJ-023, is a drug from the piprant class.