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Fludeoxyglucose (18F)
go.drugbank.com/drugs/DB09502ApprovedInvestigationalFludeoxyglucose F 18 Injection is a positron emitting radiopharmaceutical containing no-carrier added radioactive 2-deoxy-2-[18F]fluoro-D-g1ucose, which is used for diagnostic purposes in conjunction with … Positron Emission Tomography (PET).
Categories: Compounds used in a research, industrial, or household settingSynonyms: Fluorine-18 2-Fluoro-2-deoxy-D-GlucoseMiglustat
go.drugbank.com/drugs/DB00419ApprovedInvestigationalIt inhibits the enzyme glucosylceramide synthase, an essential enzyme for the synthesis of most glycosphingolipids. … It has recently been approved for treatment of progressive neurological symptoms in adult and pediatric patients in the European Union, Brazil, and South Korea.
Synonyms: N-(n-Butyl)deoxynojirimycin, N-ButylmoranolineProducts: ZAVESCA 100 MG KAPSUL, 84 ADET, ZAVESCA® 100 MGBaricitinib
go.drugbank.com/drugs/DB11817ApprovedInvestigational[A248400] The EC later approved baricitinib for the treatment of atopic dermatitis, making it the first JAK inhibitor used for this indication in Europe. … [L41760] Baricitinib was first approved by the European Commission (EC) in February 2017 for the treatment of rheumatoid arthritis in adults [A248395] and was later approved by the FDA in 2018.
Categories: MATE 2 Inhibitors, MATE 2 SubstratesProducts: UNAMİTY 2 MG FİLM KAPLI TABLET, 56 ADET, UNAMİTY 4 MG FİLM KAPLI TABLET, 56 ADETModafinil
go.drugbank.com/drugs/DB00745ApprovedInvestigationalThe exact mechanism of action is unclear, although in vitro studies have shown it to inhibit the reuptake of dopamine by binding to the dopamine reuptake pump, and lead to an increase in extracellular … Modafinil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants used in the treatment of narcolepsy.
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 SubstratesSynonyms: 2-((diphenylmethyl)sulfinyl)acetamideIsoprenaline
go.drugbank.com/drugs/DB01064ApprovedInvestigational[L33204] Isoprenaline was granted FDA approval on 19 February 1948.[L33155] … Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion
Categories: Adrenergic beta-2 Receptor Agonists, Compounds used in a research, industrial, or household settingSynonyms: 1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethanol, 1-(3,4-dihydroxyphenyl)-2-isopropylaminoethanolDiacerein
go.drugbank.com/drugs/DB11994ApprovedInvestigationalWithdrawnIt is currently approved in France for the treatment of osteoarthritis although the use of diacerein is restricted due to the side effects including severe diarrhea [L780]. … Diacerein is under investigation for the treatment of Insulin Resistance, Diabetes Mellitus (Type 2), and Diabetes-Related Complications.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsProducts: Artrolyt 50 mg Kapseln, Verboril 50 mg KapselnRoflumilast
go.drugbank.com/drugs/DB01656ApprovedInvestigational[A251385] PDE4 is a major cyclic-3',5′-adenosinemonophosphate (cyclic AMP, cAMP)-metabolizing enzyme [L37564] expressed on nearly all immune and pro-inflammatory cells, in addition to structural cells … Roflumilast is a highly selective phosphodiesterase-4 (PDE4) inhibitor.
Categories: Phosphodiesterase 4 Inhibitors, Cytochrome P-450 SubstratesProducts: ROFLUNG 0,5 MG SAŞE ,30 SAŞE, ROFLUNG 0,5 MG SAŞE ,90 SAŞEHydrocodone
go.drugbank.com/drugs/DB00956ApprovedIllicitInvestigational[T116] It is commonly used in combination with [acetaminophen] to control moderate to severe pain. … Hydrocodone's more potent metabolite, [hydromorphone] has also found wide use as an analgesic and is frequently used in cases of severe pain.
Mixtures: DOXU PLUS 10/250 MG TABLETAS RECUBIERTAS, DOXU® PLUS 10 / 250 MG TABLETAS RECUBIERTASCategories: Heterocyclic Compounds with 4 or More Rings, Cytochrome P-450 SubstratesQuinidine barbiturate
go.drugbank.com/drugs/DB01346ApprovedA papulopurpuric eruption in a patient (without thrombopenia) can be developed who is taking quinidine phenylethyl barbiturate intermittently and at reintroduction.(PMID: 9739909)
Products: NATISEDINE 100 MG TABLET, 20 ADETInterferon alfa-2b
go.drugbank.com/drugs/DB00105ApprovedInvestigationalIt is used extensively as an antiviral or antineoplastic agent. … Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23.
Synonyms: IFN alpha-2B, rIFN-alpha-2bMixtures: Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules), Rebetron Solution (albumin (human) Free) (18 Miu Multi-dose Pen / 200mg Capsules)