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Levallorphan
go.drugbank.com/drugs/DB00504ApprovedIt should be used cautiously; levallorphan reverses severe opioid-induced respiratory depression but may exacerbate respiratory depression such as that induced by alcohol or other non-opioid central depressants … An opioid antagonist with properties similar to those of naloxone; in addition it also possesses some agonist properties.
Categories: Heterocyclic Compounds with 4 or More RingsEbola Zaire vaccine (live, attenuated)
go.drugbank.com/drugs/DB15595ApprovedInvestigational[L10854] Ebola virus disease, formerly known as Ebola hemorrhagic fever, is a rare but severe and often deadly disease. … [L10866] In non-human primate clinical trials, the vaccine was effective in inducing an immune response against the Ebola viruses.
Synonyms: Ebola Zaire Vaccine (rVSV∆G-ZEBOV-GP, live), EBOLA ZAÏRE VACCINE (rVSV [DELTA] G-ZEBOV-GP, LIVE)Prenylamine
go.drugbank.com/drugs/DB04825ApprovedWithdrawnPrenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias.
Categories: Vasodilators Used in Cardiac Diseases, Cytochrome P-450 SubstratesSynonyms: N-(1-Methyl-2-phenylethyl)-gamma-phenylbenzenepropanamine, N-(3,3-Diphenylpropyl)-alpha-methylphenaethylaminZomepirac
go.drugbank.com/drugs/DB04828ApprovedWithdrawnThe manufacturer voluntarily removed Zomax tablets from the Canadian, US, and UK markets in March 1983.
Synonyms: 5-(4-Chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetic acidCategories: Non COX-2 selective NSAIDS, Analgesics, Non-NarcoticNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial
go.drugbank.com/bio_entities/BE0000305TargetHumansRequired for proper complex I assembly (PubMed:28671271). Complex I functions in the transfer of electrons from NADH to the respiratory chain. … Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
Synonyms: Complex I-39kDPhosphatidylserine synthase 1
go.drugbank.com/bio_entities/BE0001099TargetHumansCatalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine (PubMed:19014349, PubMed:24241535). Catalyzes mainly the conversion of phosphatidylchol...
Synonyms: Serine-exchange enzyme IThenalidine
go.drugbank.com/drugs/DB04826ApprovedWithdrawnWithdrawn from the Canadian, US, and UK markets in 1963 due to concerns involving neutropenia.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-Methyl-4-amino-N-phenyl-N-(2-thenyl)piperidine, 1-Methyl-4-N-2-thenylanilinopiperidineIodohippurate sodium I-131 Drug Metabolism
smpdb.ca/view/SMP0130590MetabolicIodohippurate sodium I-131 passes through the liver and is then excreted from the body mainly through the kidney. … Iodohippurate sodium I-131 is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.
Drugs: Iodohippurate sodium I-131Iodohippurate sodium I-123 Drug Metabolism
smpdb.ca/view/SMP0130602MetabolicIodohippurate sodium I-123 passes through the liver and is then excreted from the body mainly through the kidney. … Iodohippurate sodium I-123 is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.
Drugs: Iodohippurate sodium I-123Rose bengal I-131 Drug Metabolism
smpdb.ca/view/SMP0130890MetabolicRose bengal I-131 passes through the liver and is then excreted from the body mainly through the kidney. … Rose bengal I-131 is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.
Drugs: Rose bengal I-131