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Molnupiravir
go.drugbank.com/drugs/DB15661Investigational[A193026] The active drug incorporates into the genome of RNA viruses, leading to an accumulation of mutations known as viral error catastrophe. … Molnupiravir (EIDD-2801, MK-4482) is the isopropylester prodrug of [N4-hydroxycytidine].
Rimiducid
go.drugbank.com/drugs/DB04974InvestigationalIt was designed to overcome limitations of current cellular immunotherapies used for cancer and other blood disorders by enhancing the control of the immune cell activity and function. … [A187496,L9521] The combination use of rimiducid with immunotherapies for enhanced therapeutic effectiveness is currently under investigation.
Spironolactone
go.drugbank.com/drugs/DB00421ApprovedInvestigational[L44602] Off-label uses of spironolactone include hirsutism, female pattern hair loss, and adult acne vulgaris. … [A178135, A261025] Spironolactone was developed in 1957, marketed in 1959, and approved by the FDA on January 21, 1960.[A178243]
Mixtures: Lasilacton 20 mg/50 mg Kapseln, Lasilacton 20 mg/100 mg KapselnProducts: Aldactone 25 mg, Aldactone 100 mgMethenamine
go.drugbank.com/drugs/DB06799ApprovedInvestigationalVet approvedIn salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate which is the hippuric acid salt of methenamine).
Mixtures: PURINOL 250 mg+615 mg/5 g EFERVESAN 70 GR, PURINOL 250 mg+615 mg/5 g EFERVESAN 70 GRProducts: Hiprex 1g Tablet, NETURONE GRANUL LIBA, 70 GEnoxaparin
go.drugbank.com/drugs/DB01225ApprovedInvestigational[L31393] Enoxaparin markedly reduces the incidence of venous thromboembolism in hospitalized patients when compared to unfractionated [heparin], without increasing the risk of serious bleeding. … Enoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various thromboembolic disorders.
Mixtures: ENOXAPARINA SODICA 40 MG JERINGAS PRELLENADASProducts: KLEXANE 10000 IE 100MG O S, KLEXANE 4000 IE 40MG O SI.Fluocinolone acetonide
go.drugbank.com/drugs/DB00591ApprovedInvestigationalVet approved[T358] This type of device containing fluocinolone acetonide was developed by Taro Pharmaceuticals and approved by FDA in May 2016.[L4676]
Mixtures: InfectoCiproCort 3 mg/ml + 0,25 mg/ml Ohrentropfen, LösungCategories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseDesogestrel
go.drugbank.com/drugs/DB00304ApprovedInvestigationalDesogestrel, a prodrug, is a third generation progestogen[A176315] and hence, a member of the gonane family which was largely used in Europe before being approved in the US and Canada.
Mixtures: O - ZETTE, Liberel 0,15 mg/0,03 mg FilmtablettenCategories: Sex Hormones and Modulators of the Genital SystemTrifluridine
go.drugbank.com/drugs/DB00432ApprovedInvestigationalThe combination product of trifluridine with tipiracil marketed as Lonsurf has been approved in Japan, the United States, and the European Union for the treatment of adult patients with metastatic colorectal … It is an active antiviral agent in ophthalmic solutions used mainly in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to herpes simplex virus.
Mixtures: LONSURF FILM-COATED TABLET 15 MG/6.14 MG, LONSURF FILM-COATED TABLET 15 MG/6.14 MGTiludronic acid
go.drugbank.com/drugs/DB01133ApprovedVet approvedWithdrawn[A1923,A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. … [A1923] Tiludronic acid was first described in the literature in 1988 as a potential treatment for Paget's disease of bone.[A202235] Tiludronic acid was granted FDA approval on 7 March 1997.[L4763]
Categories: Drugs for Treatment of Bone DiseasesOxytetracycline
go.drugbank.com/drugs/DB00595ApprovedInvestigationalVet approvedA tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety of clinical conditions.
Mixtures: HEKSA 30 MG/G + 10000 I.U./G MERHEM, POLIMISIN GÖZ MERHEMI, 3,5 GCategories: combinations of tetracyclines