Oxytetracycline is a tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections. A tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety of clinical conditions.
- Mechanism
- Curator reviewed
Oxytetracycline inhibits cell growth by inhibiting translation. It binds to the 30S ribosomal subunit and prevents the amino-acyl tRNA from binding to the A site of the ribosome. The binding is reversible in nature. Oxytetracycline is lipophilic and can easily pass through the cell membrane or passively diffuses through porin channels in the bacterial membrane.
- Primary indication
- Oxytetracycline is indicated for treatment of infections caused by a variety of Gram positive and Gram negative microorganisms including Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae (respiratory infections), and Diplococcus pneumoniae.Curator reviewed · 5 structured indications
- Formula / weight
- C22H24N2O9 · 460.434 g/mol (avg)
- First approval
- United States, 1965
- Also known as
- 5-Hydroxytetracycline · Embryostat · Hydroxytetracyclinum · Mepatar · Oxyterracin
- Brand names
Resolves to
IWVCMVBTMGNXQD-PXOLEDIWSA-NSMILES[H][C@@]12[C@@H](O)[C@@]3([H])C(C(=O)C4=C(C=CC=C4O)[C@@]3(C)O)=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)CWhat you can answer from here — as of September 23, 2026
Which drugs share a target with Oxytetracycline, and which of those have an active Phase 3 trial?
Create a free account or log in to explore the full data card.
Create Account