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Volixibat
go.drugbank.com/drugs/DB13914Investigationalthe liver have been implicated in its pathogenesis[A32119]. … According to Shire, the pharmaceutical manufacturer of Volixibat, it has been granted fast track status by the Food and Drug Administration due to promising initial results and a need for therapeutic treatments
Categories: Heterocyclic Compounds, 2-RingVutrisiran
go.drugbank.com/drugs/DB16699ApprovedInvestigational[L42065] This siRNA therapeutic is indicated for the treatment of neuropathies associated with hereditary transthyretin-mediated amyloidosis (ATTR), a condition caused by mutations in the TTR gene. … [L34490,L42065] Vutrisiran is commercially available as a conjugate of N-acetylgalactosamine (GalNAc), a residue that enables the delivery of siRNA to hepatocytes.
Interferon beta-1a
go.drugbank.com/drugs/DB00060ApprovedInvestigationalIt is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced.
Synonyms: Interferon beta 1-a, IFN β-1aCategories: Interferon Type I, Cytochrome P-450 CYP1A2 InhibitorsBenserazide
go.drugbank.com/drugs/DB12783ApprovedInvestigationalWhen levodopa is used by itself as a therapy for treating Parkinson's disease, its ubiquitous metabolism into dopamine is responsible for a resultant increase in the levels of circulating dopamine in the … This can result in a number of side effects like nausea, vomiting, or even cardiac arrhythmias that may diminish patient adherence [F2, L2553].
Mixtures: MADOPAR®, MADOPAR®Categories: Aromatic L-amino Acid Decarboxylase InhibitorsNiacin
go.drugbank.com/drugs/DB00627ApprovedInvestigationalNutraceuticalNiacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.
Synonyms: Vitamin B-3, 3-carboxypyridineMixtures: B-KOMP ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL, 5 ADET, Formula F L WCongenital carnitine deficiency
go.drugbank.com/conditions/DBCOND0008341Drugs: LevocarnitineSynonyms: SLC22A5-gene related renal carnitine transport defectAtrasentan
go.drugbank.com/drugs/DB06199ApprovedInvestigationalAtrasentan is a novel, selective endothelin A receptor antagonist (SERA). … [L52855] In April 2025, atrasentan was granted accelerated approval by the FDA for the reduction of proteinuria in patients with primary IgA nephropathy, becoming the first endothelin A receptor antagonist
Categories: Endothelin A Receptor Antagonists, Endothelin Receptor AntagonistsEcamsule
go.drugbank.com/drugs/DB09534ApprovedEcamsule has been approved for use in the U.S. since 2006, but only at a specific concentration and only in a few products manufactured by L'Oreal. … The company got approval for those products through a new drug application process.
Mixtures: Autobronzant SPF 7, Thermal S Uv SPF 20Categories: Compounds used in a research, industrial, or household settingBaricitinib
go.drugbank.com/drugs/DB11817ApprovedInvestigationalOveractive JAKs have been implicated in autoimmune disorders, such as rheumatoid arthritis. … Baricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways.
Categories: MATE 2 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: UNAMİTY 4 MG FİLM KAPLI TABLET, 7 ADET, UNAMİTY 2 MG FİLM KAPLI TABLET, 7 ADETYellow fever vaccine
go.drugbank.com/drugs/DB10805ApprovedInvestigationalIt is composed of two live, attenuated strains of yellow fever virus, 17D-204 and 17DD, which have been shown to elicit an immune response identical to that induced by wild-type infection [FDA Label, A32118 … Yellow fever vaccine prevents against Yellow Fever, a viral hemorrhagic disease caused by the transmission of a _flavivirus_ through the bite of an infected mosquito.
Synonyms: Yellow fever virus live antigen, AProducts: STAMARIL ®, STAMARIL 0,5 ML IM/SC ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON VE ÇÖZÜCÜ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET