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Displaying results 111 - 120 of 151544 in total
  1. Drug

    Ursodeoxycholic acid

    go.drugbank.com/drugs/DB01586
    ApprovedInvestigational

    [A256272] UDCA was first approved by the FDA in 1987 for dissolution of gallstones and for primary biliary cirrhosis in 1996. … [A256267,A256463] UDCA was first characterized in the bile of the Chinese black bear and is formed by 7b-epimerization of [chenodeoxycholic acid], which is a primary bile acid.

    Synonyms: Ursodeoxycholic acid, (3α,5β,7β)-3,7-dihydroxycholan-24-oic acidCategories: Bile Acids and Salts, Bile acids and derivatives
  2. Drug

    AMG 424

    go.drugbank.com/drugs/DB17357
    Investigational

    AMG 424 is a novel, humanized, anti-CD3/CD38 bispecific monoclonal antibody being investigated for multiple myeloma.

    Synonyms: Humanized Bi-Specific Xmab(R) T Cell Recruiting Antibody Construct Directed Against Cd3 And Cd38
  3. Drug

    Mycophenolic acid

    go.drugbank.com/drugs/DB01024
    ApprovedInvestigational

    [A249180] However, mycophenolic acid treatment is more expensive and requires therapeutic drug monitoring to optimize efficacy and minimize toxicity. … [A249180,A249185] Mycophenolic acid is available as enteric-coated tablets of delayed-release, in an effort to improve upper gastrointestinal adverse events by delaying mycophenolic acid release until

    Categories: Mycophenolic Acid and Prodrugs, Antineoplastic and Immunomodulating AgentsSynonyms: Mycophenolic acid, Acido micofenolico
  4. Drug

    Clodronic acid

    go.drugbank.com/drugs/DB00720
    ApprovedInvestigationalVet approved

    Clodronic acid is a first generation bisphosphonate similar to [etidronic acid] and [tiludronic acid]. … [A1923] clodronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate [zoledronic acid], [ibandronic acid], [minodronic acid], and [risedronic acid]

    Categories: Drugs Affecting Bone Structure and Mineralization, clodronic acidSynonyms: Clodronic acid, (dichloromethylene)bisphosphonic acid
  5. Drug

    Etacrynic acid

    go.drugbank.com/drugs/DB00903
    ApprovedInvestigational

    A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. … This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.

    Categories: etacrynic acid, Aryloxyacetic Acid DerivativesSynonyms: Etacrinic acid, Etacrynic acid
  6. Drug

    Anbenitamab

    go.drugbank.com/drugs/DB18411
    Investigational

    Synonyms: FC-fusion bispecific antibody targeting extracellular domains II and IV of HER 2 and FC-fusion bispecific IgG1 antibody inhibiting PD-L1 and CTLA-4
  7. Drug

    Lactic acid

    go.drugbank.com/drugs/DB04398
    ApprovedInvestigationalVet approved

    (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste. … It is produced by fermentation of a sugar source, such as corn or beets, and then, by neutralizing the resulting lactic acid to create a compound having the formula NaC3H5O3.

    Synonyms: Milk acid, Lactic acidMixtures: Lactic Acid 30% / Salicylic Acid 30%, Dextrose and Electrolyte No. 75
  8. Drug

    TN-201

    go.drugbank.com/drugs/DB18700
    Investigational

    TN-201 is a gene therapy comprising a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human MYBPC3 gene.

    Synonyms: Native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human MYBPC3 gene
  9. Drug

    Acetic acid

    go.drugbank.com/drugs/DB03166
    ApprovedInvestigational

    (Stedman, 26th ed) Acetic acid otic (for the ear) is an antibiotic that treats infections caused by bacteria or fungus. … Acetic acid is a product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent.

    Synonyms: Acetic acid, Ethoic acidMixtures: Hydrocortisone and Acetic Acid, Hydrocortisone and Acetic Acid
  10. Drug

    Selenious acid

    go.drugbank.com/drugs/DB11127
    Approved

    Selenious acid is the acid form of sodium selenite, a form of selenium [L1910]. Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation. … It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant properties.

    Synonyms: Selenous acid, Selenious acidMixtures: Formula F L W, Vitamin and Mineral Drink Mix