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Trazodone
go.drugbank.com/drugs/DB00656ApprovedInvestigationalTrazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors (SARIs) class of antidepressants. It is used in adults and has been shown to be comparable in efficacy to other drugs such as tricyc...
Categories: P-glycoprotein inducers, Cytochrome P-450 SubstratesProducts: Nu-trazodone - Tab 50mg, Nu-trazodone - Tab 100mgChondroitin sulfate
go.drugbank.com/drugs/DB09301ApprovedInvestigationalNutraceuticalChondroitin sulfate is composed of alternating 1,3-N-acetyl-β-d-galactosamine and 1,4-β-d-glucuronic acid units which bear 4-O- and/or 6-O-sulfations at the N-acetylgalactosamine units disposed of in specific
Mixtures: CARTIGEN NFProducts: Nn Bio Chondroitin 400Nimesulide
go.drugbank.com/drugs/DB04743ApprovedWithdrawnNimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: SEVERIN NF, NI-M-DOL® (NIMESULIDA SUSPENSION)Clonidine
go.drugbank.com/drugs/DB00575ApprovedInvestigationalClonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors. This activity is useful for the treatment of hypertension, severe pain, and ADHD. Clonidine was granted FDA approval on 3 September 1974.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 2,6-Dichloro-N-2-imidazolidinylidenebenzenamineFluvastatin
go.drugbank.com/drugs/DB01095ApprovedInvestigationalFluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynth...
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 CYP1A1 SubstratesProducts: FLUVASTATIN 1A PH 80MG RETOctinoxate
go.drugbank.com/drugs/DB09496ApprovedInvestigationalOctinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage. It was originally developed in 1950's as an organic UV-B filter that absorbs UV-B rays from sun. It is often com...
Mixtures: Provence Foundation Spf31 Pa Plus Plus No 23, Provence Foundation Spf31 Pa Plus Plus No 21Synonyms: ethylhexyl p-methoxycinnamateGuaifenesin
go.drugbank.com/drugs/DB00874ApprovedInvestigationalVet approvedGuaifenesin possesses a storied history, having been originally formally approved by the US FDA in 1952 and continues to be one of very few - if not perhaps the only drug that is readily available and used as an expectorant . Since that ...
Mixtures: Nu-copd, Ganituss NrProducts: Organ-I Nr, Organidin NRNaphazoline
go.drugbank.com/drugs/DB06711ApprovedNaphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles . It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations . Naphazoline was firs...
Mixtures: OSMOCROM-N ®Products: DURAULTRA N SINE, Pi Yen ChinAnti-inhibitor coagulant complex
go.drugbank.com/drugs/DB13151ApprovedInvestigationalAnti-inhibitor coagulant complex, also known as FEIBA (factor eight inhibitor bypassing activity), contains several proteins involved in the prothrombinase complex. It is used to control bleeding in hemophilia A and B patients with inhib...
Products: Feiba NfSelegiline
go.drugbank.com/drugs/DB01037ApprovedInvestigationalVet approvedA selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: Nu-selegiline