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Nifedipine
go.drugbank.com/drugs/DB01115ApprovedInvestigationalNifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine. Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972....
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: Nu-nifedipine-PA, Nu-nifedipine-PA - Prolonged Action TabCholecalciferol
go.drugbank.com/drugs/DB00169ApprovedInvestigationalNutraceuticalStructurally, ergocalciferol differs from cholecalciferol in that it possesses a double bond between C22 and C23 and has an additional methyl group at C24 [L5689]. … Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are considered the
Synonyms: (+)-vitamin D3, Vitamin D3International brands: Delta-D, Micro-DCaspofungin
go.drugbank.com/drugs/DB00520ApprovedInvestigationalIt shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal cell wall. … Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug class called the echinocandins, as coined by Merck & Co., Inc.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsSynonyms: (4R,5S)-5-((2-Aminoethyl)amino)-N(sup 2)-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-transDaptomycin
go.drugbank.com/drugs/DB00080ApprovedInvestigational[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked ring and the N-terminal … [A231384] Early work on developing daptomycin was abandoned due to observed myopathy but was resumed in 1997 when Cubist Pharmaceuticals Inc. licensed daptomycin; it was found that a once-daily dosing
Categories: P-glycoprotein substratesProducts: DAPTOMICINA DR. REDDY'S, DAPTOMRED 350 MG/VIALPemetrexed
go.drugbank.com/drugs/DB00642ApprovedInvestigationalPemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta. It is indicated for use in combination with cisplatin for the treatment of patients with malignant pleural mesothel...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: PEMETREXED DR. REDDY'S, PEMGEM 500MG/VIALMagnesium hydroxide
go.drugbank.com/drugs/DB09104ApprovedInvestigationalMagnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form. … Magnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite.
Synonyms: Hidroxido de magnesioMixtures: ConRx AR, Mag-AlAluminum chloride
go.drugbank.com/drugs/DB11081ApprovedInvestigationalIt may also be found in over-the-counter as an antiperspirant or prescription products as an antihemorrhagic agent. … In antiperspirant products, FDA approves the use of aluminum chloride as an active ingredient up to 15%, calculated on the hexahydrate form, in an aqueous solution nonaerosol dosage form [L2012].
Products: Dr Sweat, Duradry PMPrednisolone acetate
go.drugbank.com/drugs/DB15566ApprovedInvestigationalVet approvedPrednisolone acetate is a [prednisolone] molecule bound to an acetate functional group by an ester bond.[L9449] Prednisolone acetate was granted FDA approval in 1955.[L9449]
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: NISOL INJECTION (10ML VIAL), Prednisolone Acetate PFHepatitis B Vaccine (Recombinant)
go.drugbank.com/drugs/DB11627ApprovedInvestigationalWithdrawnViral hepatitis caused by hepatitis B virus is a major worldwide health problem, though the incidence and epidemiology vary widely among geographical areas and population subgroups. … Hepatitis D virus, a defective virus requiring the “keeper function” of the hepatitis B virus, occurs either as a co-infection or super-infection in a HBsAg carrier.
Products: BRECO-VAC, H-VAC ERISKIN 1 ML IM ENJEKSIYON ICIN SUSPANSIYON ICEREN AMPULPiperacillin
go.drugbank.com/drugs/DB00319ApprovedInvestigationalSemisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. It is also used in combination with other antibiotics.
Mixtures: TAZPEN FOR INJECTION 4.5g/VIAL, TAZOCIN FOR INJECTION 4.5 g/vialProducts: Pipracil Pharmacy Bulk Vial-pws IV 40g/vial, Pipracil Inj 2gm/vial