Search

Displaying results 111 - 120 of 2501 in total
  1. Drug

    Chloroxylenol

    go.drugbank.com/drugs/DB11121
    Approved

    Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments. It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. ...

    Synonyms: p-chloro-m-xylenol, p-chloro-3,5-xylenolProducts: Ps-1000, Purgo Ultra PC
  2. Drug

    Ibuprofen

    go.drugbank.com/drugs/DB01050
    ApprovedInvestigational

    Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in ...

    Mixtures: Advil PM, Advil PMCategories: P-glycoprotein inhibitors, P-glycoprotein substrates
  3. Drug

    Toripalimab

    go.drugbank.com/drugs/DB15043
    ApprovedInvestigational

    One mechanism by which this occurs is through the overexpression of programmed cell death ligand (PD-L1)[A261506] - the binding of PD-L1 (and PD-L2) to its target receptor (PD-1) results in the inhibition … [L48681] Toripalimab is a selective, recombinant, humanized IgG4 monoclonal antibody targeted against the PD-1 receptor.

    Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors
  4. Drug

    Gepirone

    go.drugbank.com/drugs/DB12184
    Approved

    Gepirone, an azapirone, is a pharmacologic analog of [buspirone] that acts selectively on the pre- and post-synaptic 5HT<sub>1A</sub> receptors.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  5. Drug

    Cemiplimab

    go.drugbank.com/drugs/DB14707
    ApprovedInvestigational

    By blocking PD-1, cemiplimab works to enhance T cell-mediated antitumour responses. … Cemiplimab is a fully human monoclonal antibody that works against programmed death receptor-1 (PD-1), which is a negative regulator of T cell function.

    Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors
  6. Drug

    Atezolizumab

    go.drugbank.com/drugs/DB11595
    ApprovedInvestigational

    Atezolizumab is a programmed death-ligand 1 (PD-L1) blocking antibody indicated for non-small cell lung cancer, small cell lung cancer, hepatocellular carcinoma, melanoma, alveolar soft part sarcoma, muscle

    Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors
  7. Drug

    Zalospirone

    go.drugbank.com/drugs/DB19481
    Experimental

    The usage of the INN stem '-pirone' in the name indicates that Zalospirone is a anxiolytic, buspirone derivative. Zalospirone has a monoisotopic molecular weight of 419.23 Da.

  8. Drug

    Alnespirone

    go.drugbank.com/drugs/DB19784
    Experimental

    The usage of the INN stem '-pirone' in the name indicates that Alnespirone is a anxiolytic, buspirone derivative. Alnespirone has a monoisotopic molecular weight of 442.28 Da.

  9. Drug

    Eptapirone

    go.drugbank.com/drugs/DB19836
    Experimental

    The usage of the INN stem '-pirone' in the name indicates that Eptapirone is a anxiolytic, buspirone derivative. Eptapirone has a monoisotopic molecular weight of 345.19 Da.

  10. Drug

    Revospirone

    go.drugbank.com/drugs/DB20158
    Experimental

    The usage of the INN stem '-pirone' in the name indicates that Revospirone is a anxiolytic, buspirone derivative. Revospirone has a monoisotopic molecular weight of 387.14 Da.