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Displaying results 111 - 120 of 158651 in total
  1. Drug

    Aminolevulinic acid

    go.drugbank.com/drugs/DB00855
    ApprovedInvestigational

    A compound produced from succinyl-CoA and glycine as an intermediate in heme synthesis. It is used as a photochemotherapy for actinic keratosis. [PubChem]

    Synonyms: 5-ALA, 5-Aminolevulinic acidCategories: Amino Acids, Peptides, and Proteins, Skin and Mucous Membrane Agents
  2. Drug

    3-(10-methyl-9-anthryl)propanoic acid

    go.drugbank.com/drugs/DB07371
    Experimental

    Synonyms: 3-(10-methyl-9-anthryl)propanoic acid, 3-(10-methyl-9-anthryl)propionic acid
  3. Drug

    Secobarbital

    go.drugbank.com/drugs/DB00418
    ApprovedVet approved

    Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties.

    Synonyms: 5-(1-methylbutyl)-5-(2-propenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione, 5-allyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrioneCategories: Heterocyclic Compounds, 1-Ring, Hypnotics and Sedatives
  4. Drug

    5-O-phosphono-alpha-D-ribofuranosyl diphosphate

    go.drugbank.com/drugs/DB01632
    ApprovedWithdrawn

    The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.

    Synonyms: 5-Phosphoribosyl 1-pyrophosphate, 5-Phospho-alpha-D-ribose 1-diphosphate
  5. Drug

    Carbamazepine

    go.drugbank.com/drugs/DB00564
    ApprovedInvestigational

    [A180301] Aside from the above uses, this drug is also given to control the symptoms of bipolar 1. … Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia.

    Synonyms: 5-Carbamoyl-5H-dibenz(b,f)azepine, 5-carbamoyl-5H-dibenz[b,f]azepineCategories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index
  6. Drug

    Mesalazine

    go.drugbank.com/drugs/DB00244
    ApprovedInvestigational

    Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical agent … Throughout the late seventies and the eighties, important research initiatives developed stable mesalazine formulations like the eudragit-S coating of Asacol brand mesalazine and the Pentasa brand's encapsulation

    Synonyms: m-Aminosalicylic acid, 5-ASAProducts: KOLESA 250 MG SUPOZİTUVAR, 10 ADET, SALOFALK 250 MG SUPOZITUAR, 10 ADET
  7. Drug

    Linaclotide

    go.drugbank.com/drugs/DB08890
    ApprovedInvestigational

    Linaclotide is a synthetic 14-amino acid cyclic peptide [A260271] and first-in-class guanylate cyclase-C (G-CC) agonist. … Linaclotide was first approved by the FDA on August 30, 2012.[A260271] It gained EMA and Health Canada approval on November 26, 2012 [L47216] and December 3, 2013,[L47221] respectively.

    Categories: Alimentary Tract and Metabolism, Guanylate Cyclase-C AgonistSynonyms: -GLUTAMYL-L-TYROSYL-L-CYSTEINYL-L-CYSTEINYL-L-ASPARAGINYL-L-PROLYL-L-ALANYL-L-CYSTEINYL-L-THREONYLGLYCYL-L-CYSTEINYL-, CYCLIC (1->6),(2->10),(5->13)-TRIS(DISULFIDE), (9-L-TYROSINE)HEAT-STABLE ENTEROTOXIN (ESCHERICHIA COLI)-(6-19)-PEPTIDE
  8. Drug

    Homidium

    go.drugbank.com/drugs/DB17031
    Investigational

    Homidium is a group II compound with trypanocidal effects.[A253017]

    Synonyms: 2,7-diamino-10-ethyl-9-phenylphenanthridinium, 2,7-diamino-9-phenyl-10-ethylphenanthridiniumCategories: Indicators and Reagents, Heterocyclic Compounds, 3-Ring
  9. Drug

    Estrone sulfate

    go.drugbank.com/drugs/DB04574
    Approved

    Estrone sulfate (as estropipate) is a form of estrogen. … postmenopausal women), treatment of prostate cancer and prevention of osteoporosis.

    Synonyms: Estra-1,3,5 (10)-triene-17-one-3-yl-sulfate, Estrone 3-sulfateMixtures: Esterified Estrogens and Methyltestosterone, Esterified Estrogens and Methyltestosterone
  10. Drug

    Leflunomide

    go.drugbank.com/drugs/DB01097
    ApprovedInvestigational

    Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous. … Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999.

    Categories: Heterocyclic Compounds, 1-Ring, Leflunomide and metaboliteSynonyms: 4-ISOXAZOLECARBOXAMIDE, 5-METHYL-N-(4-(TRIFLUOROMETHYL)PHENYL)-, 5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide