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Fulvestrant
go.drugbank.com/drugs/DB00947ApprovedInvestigationalIt is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor.
Categories: EstranesSynonyms: (7α,17β)-7-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17-diolNo disease progression after platinum-based chemotherapy
go.drugbank.com/conditions/DBCOND0127683Synonyms: No disease progression after platinum-based chemotherapySymptomatic for no more than two days
go.drugbank.com/conditions/DBCOND0023927Drugs: PeramivirSynonyms: Symptomatic for no more than two daysNitrofurantoin
go.drugbank.com/drugs/DB00698ApprovedInvestigationalVet approved[L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. … [A179824] This drug is more resistant to the development of bacterial resistance because it acts on many targets at once.
Synonyms: N-(5-Nitrofurfurylidene)-1-aminohydantoinProducts: NEO FURADANTIN, Nu-nitrofurantoin TabletsBudesonide
go.drugbank.com/drugs/DB01222ApprovedInvestigational[A188529,A188532] Budesonide was granted FDA approval on 14 February 1994.[L10598] It is also available in a combination product with [formoterol].[L10619] … Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.
Categories: Agents to Treat Airway DiseaseProducts: AEROSIAL N, NEO - RINACTIVELevothyroxine
go.drugbank.com/drugs/DB00451ApprovedInvestigational[F4633] T<sub>4</sub> and T<sub>3</sub> act on nearly every cell of the body, but have a particularly strong effect on the cardiac system. … However, this is no longer recommended for the majority of patients due to several clinical concerns including limited controlled trials supporting its use.
Mixtures: Np Thyroid 90, NP Thyroid 30Categories: Agents used to treat hypothyroidismHydroquinone
go.drugbank.com/drugs/DB09526ApprovedInvestigationalIt can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids, or sunscreen. … Hydroquinone has come under scrutiny due to several complications associated with its use, including dermal irritation, exogenous onchronosis, and carginogenicity.
Mixtures: Throwers Pbc No. 1, Obagi Nu-Derm SunfaderProducts: SLMD Skincare by Sandra Lee, M.D. - Dark Spot Fix, Obagi Nu-DermCalcium acetate
go.drugbank.com/drugs/DB00258ApprovedIt has been commonly referred to as the acetate of lime. The anhydrous form is very hygroscopic, therefore the monohydrate is the common form.
Products: PHOS-NO 1000 MG TABLET, 180 ADETTrimipramine
go.drugbank.com/drugs/DB00726ApprovedInvestigationalTricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.
Categories: Non-Selective Monoamine Reuptake Inhibitors, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: 10,11-dihydro-N,N,β-trimethyl-5H-dibenz[b,f]azepine-5-propanamineValproate bismuth
go.drugbank.com/drugs/DB13910ApprovedValproate bismuth is available in Canada in the over-the-counter medication Neo-Laryngobis.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: Neo-laryngobis, Neo Laryngobis Enf