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Bisoprolol
go.drugbank.com/drugs/DB00612ApprovedInvestigationalA180472] Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and is a useful alternative to non-selective β-blocker drugs in the treatment of hypertension such as … [A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs.
Mixtures: BISOBETA COMP 10MG/25MG, BIRAMLO 10MG/5MGProducts: BISO LICH 10MG, BISOHEXAL 10MGIsosorbide mononitrate
go.drugbank.com/drugs/DB01020ApprovedInvestigational[L11743] Isosorbide mononitrate has a longer duration of action than [nitroglycerin] due to its slow onset of absorption and metabolism. … It is an anti-anginal agent that works by relaxing the smooth muscles of both arteries and veins, but but predominantly veins to reduce cardiac preload.
Products: ISMN - CT 20MG TABLETTEN, IS 5 MONO RATIO 40MG RETEsomeprazole
go.drugbank.com/drugs/DB00736ApprovedInvestigationalIt can also be found in quadruple regimens for the treatment of _H. pylori_ infections along with other antibiotics including [DB01060], [DB01211], and [DB00916], for example. … Esomeprazole exerts its stomach acid-suppressing effects by preventing the final step in gastric acid production by covalently binding to sulfhydryl groups of cysteines found on the (H+, K+)-ATPase enzyme at
Mixtures: VIMOVO 500MG/20MG MODIFIED-RELEASE TABLETSInternational brands: ES-ODCyclobenzaprine
go.drugbank.com/drugs/DB00924ApprovedInvestigational[A184982] It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from [Amitriptyline] by only a single double bond. … [A185039,A184982] Since its approval, it has remained relatively popular as an adjunctive, short-term treatment for acute skeletal muscle spasms secondary to musculoskeletal injury.
Mixtures: Cyclo/Mag 10mg/200mg, CLONIXINATO / CICLOBENZAPRINA 125MG/5MGProducts: PMS-cyclobenzaprine - Tab 10mg, Flexeril -(10mg)Fluoxetine
go.drugbank.com/drugs/DB00472ApprovedInvestigationalVet approved[A181673] It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies … Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI).
Mixtures: TARGET 12MG /25 MG KAPSUL, 90 ADET, TARGET 12MG /50 MG KAPSUL, 90 ADETProducts: Prozac Capsules 10mg, Dom-fluoxetine - Cap 10mgChlordiazepoxide
go.drugbank.com/drugs/DB00475ApprovedIllicitIt has also been used in the symptomatic treatment of alcohol withdrawal.
Products: Corax Cap 10mg, Novo-poxide 10mgCisapride
go.drugbank.com/drugs/DB00604ApprovedWithdrawnIn many countries (including Canada) cisapride has been either withdrawn or has had its indications limited due to reports about long QT syndrome due to cisapride, which predisposes to arrhythmias.
Products: Prepulsid Tab 10mg, CISAPRIDA TABLETAS 10MGDiazepam
go.drugbank.com/drugs/DB00829ApprovedIllicitInvestigationalVet approvedIt is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal … (From Martindale, The Extra Pharmacopoeia, 30th ed, p589) Given diazepam's storied history as a commonly used and effective medication for a variety of indications, contemporary advancements in the
Products: E Pam Tab 10mg, E Pam Tab 2mgMethylprednisolone
go.drugbank.com/drugs/DB00959ApprovedInvestigationalVet approved[A188811] It was first described in the literature in the late 1950s.[A188811,A188814] Methylprednisolone was granted FDA approval on 24 October 1957. … [L10785] In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with long-term immunosuppression.
Mixtures: Physicians EZ Use M-pred, Physicians EZ Use M-predProducts: URBASON 40MG, METYPRED 40MG GALENIsotretinoin
go.drugbank.com/drugs/DB00982ApprovedInvestigational[Label] It was most widely marketed under the brand name Accutane, which has since been discontinued. … [L6579] The first isotretinoin-containing product was FDA approved on 7 May 1982.[L6574]
Products: ISOFACE 40MG, ISODERM 10MG