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Allylestrenol
go.drugbank.com/drugs/DB01431InvestigationalIt is widely marketed throughout Europe, including Russia and many other European countries, and is also available in Japan, Hong Kong, India, Bangladesh, Indonesia, and much of Southeast Asia, though … A synthetic steroid with progestational activity.
Synonyms: 17α-allylestr-4-en-17β-ol, 3-deketo-17α-allyl-19-nortestosteroneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesEdoxudine
go.drugbank.com/drugs/DB13421ApprovedWithdrawnEdoxudine is a deoxythymidine analog with activity against herpes simplex virus. It is a potent and selective inhibitor of herpes simplex virus type 1 and 2. … It was later recognized to be effective in vivo in a preclinical model of keratitis caused by herpes virus.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 2'-Deoxy-5-ethyluridine, 5-Ethyl-2'-deoxyuridineEtodolac
go.drugbank.com/drugs/DB00749ApprovedInvestigationalVet approvedEtodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. … It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.
Mixtures: S-ETODUO 150/300 MG FİLM KAPLI TABLET, 10 ADET, S-ETODUO 150/300 MG FİLM KAPLI TABLET, 14 ADETCategories: COX-2 Inhibitors, Cytochrome P-450 SubstratesDexloxiglumide
go.drugbank.com/drugs/DB04856InvestigationalDexloxiglumide is a selective cholecystokinin type A (CCKA) receptor antagonist in phase III testing by Rottapharm in Europe only, as U.S. trials have been discontinued. … As the D-isomer of loxiglumide, it retains all pharmacological properties of loxiglumide but is more potent.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesType 2 Diabetes
go.drugbank.com/conditions/DBCOND0030616Propofol
go.drugbank.com/drugs/DB00818ApprovedInvestigationalVet approvedIV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. … Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia.
Synonyms: 2,6-bis(1-methylethyl)phenolMixtures: Anesthesia S/I-60, Anesthesia S/I-40Sennosides
go.drugbank.com/drugs/DB11365ApprovedInvestigationalIt is a weaker laxative than bisacodyl or castor oil[A177092]. … Sennosides (also known as senna glycoside or senna) is a medication used to treat constipation[FDA Label][L771] and empty the large intestine before surgery.
Salts: Sennosides A and BMixtures: Senna-S, Senexon-SGluconic Acid
go.drugbank.com/drugs/DB13180ApprovedInvestigationalGluconic acid or gluconate is used to maintain the cation-anion balance on electrolyte solutions.
Synonyms: D-Gluconic AcidMixtures: Isolyte S, Isolyte S pH 7.4Sodium phosphate, dibasic
go.drugbank.com/drugs/DB14502ApprovedInvestigationalSynonyms: Phosphoric acid, sodium salt (1:2)Mixtures: ISOLYTE-S PH 7.4 PVC 500 ML(SETLI), ISOLYTE-S PH 7.4 PVC 1000 ML(SETLI)Ivosidenib
go.drugbank.com/drugs/DB14568ApprovedInvestigationalIvosidenib is a first-in-class isocitrate dehydrogenase-1 (IDH1) inhibitor. … The drug is only effective in patients with a susceptible IDH1 mutation.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index