Search

Displaying results 1191 - 1200 of 10000 in total
  1. Drug

    RUS 3108

    go.drugbank.com/drugs/DB05911
    Experimental

    The drug’s Phase I clinical trials have been initiated in Europe to assess safety of the drug compound in healthy volunteers. … RUS 3108 is being developed for the treatment of atherosclerosis, the major cause of cardiovascular disorders such as heart attacks and stroke by Dr. Reddy’s Laboratories.

  2. Drug

    Masitinib

    go.drugbank.com/drugs/DB11526
    InvestigationalVet approved

    Masitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in dogs. It has been available in Europe since 2009, under the brand name Masivet. … In the USA it is distributed under the name Kinavet and has been available for veterinaries since 2011.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-((4-METHYLPIPERAZIN-1-YL)METHYL)-N-(4-METHYL-3-((4-PYRIDIN-3-YL-1,3-THIAZOL-2-YL)AMINO)PHENYL)BENZAMIDE
  3. Drug

    Aceclofenac

    go.drugbank.com/drugs/DB06736
    Approved

    It is a more commonly prescribed drug in Europe. … Aceclofenac is also reported to be effective in other painful conditions such as dental and gynaecological conditions [A19672].

    Mixtures: ZERODOL PCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Substrates
  4. Drug

    TrenibotulinumtoxinE

    go.drugbank.com/drugs/DB19082
    Approved

    [L64118] It is the first and only rapid-onset, short-duration botulinum neurotoxin serotype E approved in Europe.[L64118] … and resolve within 2 to 3 weeks.

    Synonyms: BOTULINUM NEUROTOXIN SEROTYPE E (BONT/E) (EB-001), BONTOXILYSIN-E
  5. Drug

    Thonzonium

    go.drugbank.com/drugs/DB09552
    Approved

    Thonzonium is a monocationic surface-active agent with surfactant and detergent properties. … A common pharmaceutical formulation of thonzonium bromide is cortisporin-TC ear drops. It is also reported that thonzonium also confers an antifungal property and antiresorptive effect on bone.

    Mixtures: Coly-Mycin S, Coly-Mycin SCategories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Citrus bioflavonoids

    go.drugbank.com/drugs/DB14586
    Approved

    Mixtures: Kordel"s Kid"s Vitamin C 250 mg + Bioflavonoids Chewable Tablet, KORDEL`S NUTRITIME TABLETCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  7. Pathway

    Fenoldopam Mechanism of Action Action Pathway

    smpdb.ca/view/SMP0126645
    Drug action

    The R-isomer has approximately 250-fold higher affinity for D1-like receptors than does the S-isomer.

    Drugs: ATP · Fenoldopam · Calcium · Magnesium cation · Cyclic adenosine monophosphate · Pyrophosphoric acid
    Enzymes: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
  8. Drug

    Influenza B virus B/Colorado/06/2017 live (attenuated) antigen

    go.drugbank.com/drugs/DB14697
    ApprovedWithdrawn

    A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3.

    Synonyms: Influenza B virus B/Colorado/06/2017 live (attenuated) antigenMixtures: INFLUVAC S, INFLUVAC S
  9. Drug

    Inclisiran

    go.drugbank.com/drugs/DB14901
    ApprovedInvestigational

    [A225953,A225958] On December 11, 2020, the European Commission (EC) granted authorization for marketing inclisiran as the first and only approved siRNA for the treatment of adults with primary hypercholesterolemia … is a major known risk factor for CVD.

    Categories: Compounds used in a research, industrial, or household setting, Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) InhibitorsProducts: LYPTİMZİA 284 MG/1,5 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET
  10. Drug

    Bictegravir

    go.drugbank.com/drugs/DB11799
    ApprovedInvestigational

    Bictegravir is a recently approved investigational drug that has been used in trials studying the treatment of HIV-1 and HIV-2 infection. … It has been approved for HIV-1 monotherapy combined with 2 other antiretrovirals in a single tablet.[L43677]

    Categories: MATE 1 Inhibitors, Cytochrome P-450 Substrates