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Golodirsen
go.drugbank.com/drugs/DB15593ApprovedInvestigationalThis is an X-linked condition leading to progressive muscle degeneration that begins in early childhood, rendering many patients wheelchair-bound by age 12. … [A188580,T756] A similar drug used in the treatment of other types of DMD is [eteplirsen], which targets a different genetic mutation.
Categories: Compounds used in a research, industrial, or household settingDupilumab
go.drugbank.com/drugs/DB12159ApprovedInvestigationalIt was first approved by the FDA in 2017. … [L41900] It is used as monotherapy or in combination with other drugs, such as corticosteroids.
Categories: Skin and Mucous Membrane AgentsProducts: Dupixent 300 mg Solution for Injection in Pre-filled Syringe, Dupixent 200mg Solution for Injection in Pre-Filled SyringeTechnetium Tc-99m pertechnetate
go.drugbank.com/drugs/DB09314ApprovedInvestigationalThis is normally supplied in a hospital setting through the use of a technetium-99m generator, whereby technetium exits the generator in the form of the pertechnetate ion, TcO4−, which can be extracted … It also concentrates in the thyroid gland, salivary glands, gastric mucosa, and choroid plexus.
Categories: Compounds used in a research, industrial, or household settingDimercaprol
go.drugbank.com/drugs/DB06782ApprovedIn addition, it has in the past been used for the treatment of Wilson's disease, a genetic disorder in which the body tends to retain copper. … It was developed as an experimental antidote against the arsenic-based poison gas Lewisite. It has been used clinically since 1949 in arsenic, cadmium and mercury poisoning.
Categories: Compounds used in a research, industrial, or household settingInternational brands: Bal In Oil InjectionEpinephrine
go.drugbank.com/drugs/DB00668ApprovedInvestigationalVet approvedThough it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been available since 1987 in the USA. … It can be used in severe cases of croup [L4824].
Mixtures: Pro Numb Sensitive Skin, Marcaine ECategories: Sympathomimetics in Glaucoma TherapyWithdrawal Symptoms
go.drugbank.com/conditions/DBCOND0068142Drugs: PhenobarbitalSynonyms: Withdrawal sign or symptom (finding)Nitrogen
go.drugbank.com/drugs/DB09152ApprovedInvestigationalVet approvedLiquid nitrogen is used principally in cryotherapy for removal of diseased skin. … Liquid nitrogen helps in removal of skin lesions through necrosis, which results from the freezing and thawing of cells. Cryotherapy usually done in doctors' office.
Mixtures: Co-NE-O2-N2 Mixture, Lung Diffusion Test Mix No Ne CoProducts: N/AAdapalene
go.drugbank.com/drugs/DB00210ApprovedInvestigational[A193521] [Tazarotene] is more efficacious than adapalene but is designated as pregnancy category X and hence is contraindicated in pregnant women. … On December 8th, 2008, Galderma Labs gained FDA approval for Epiduo®, a 0.1% adapalene, 2.5% BPO combination gel.[L12873]
Categories: Retinoids for Topical Use in Acne, Skin and Mucous Membrane AgentsEdaravone
go.drugbank.com/drugs/DB12243ApprovedInvestigational[L44007] It was later approved for the treatment of amyotrophic lateral sclerosis (ALS) in Japan and South Korea in 2015, followed by the FDA approval in May 2017 [L41810] and Health Canada approval in … [L44007] The oral suspension formulation of edaravone was approved by the FDA in May 2022 and by Health Canada in November 2022.
Categories: Compounds used in a research, industrial, or household settingLevoleucovorin
go.drugbank.com/drugs/DB11596ApprovedInvestigationalHowever, in order to function in this role, it must first be reduced by the enzyme dihydrofolate reductase (DHFR) into the cofactors dihydrofolate (DHF) and tetrahydrofolate (THF). … Levoleucovorin, as the product Fusilev (FDA), has an additional indication for use in combination chemotherapy with 5-fluorouracil in the palliative treatment of patients with advanced metastatic colorectal
Categories: Compounds used in a research, industrial, or household setting, Vitamin B ComplexSynonyms: N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid