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Sodium feredetate
go.drugbank.com/drugs/DB13381ApprovedSynonyms: Feredato de sodio, Ferédétate de sodiumMixtures: Bal-Care DHA, Cavan-EC SOD DHAPyridoxal phosphate
go.drugbank.com/drugs/DB00114ApprovedInvestigationalNutraceuticalThis is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid.
Mixtures: BumP DHA, BumP DHADoxorubicin
go.drugbank.com/drugs/DB00997ApprovedInvestigational[A257709] Although its detailed molecular mechanisms have yet to be understood, doxorubicin is generally thought to exert its effect through DNA intercalation, which eventually leads to DNA damage and … [A257614] Thanks to its efficacy and broad effect, doxorubicin was approved by the FDA in 1974 to treat a variety of cancer, including but not limited to breast, lung, gastric, ovarian, thyroid, non-Hodgkin
Categories: BSEP/ABCB11 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: DOXORRUBICINA CLORHIDRATO 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE., DOXORUBICINA CLORHIDRATO POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE X 50 MGLazertinib
go.drugbank.com/drugs/DB16216ApprovedInvestigational[A264289] It was approved by the FDA on August 19, 2024.[L51189] Lazertinib is used alone or in combination with other chemotherapeutic agents.[L51184]
DAR-0100A
go.drugbank.com/drugs/DB16139InvestigationalDAR-0100A is under investigation in clinical trial NCT01466205 (Clinical Testing of a D1 Agonist for Cognitive Enhancement in Schizotypal Personality Disorder).
Categories: Dopamine D1 Receptor AgonistsTemozolomide
go.drugbank.com/drugs/DB00853ApprovedInvestigationalleading to DNA lesions and eventual apoptosis. … Despite considerable genetic heterogeneity, these tumours often have impaired DNA repair systems, rendering them initially sensitive to alkylating agents, although they invariably develop resistance to
Categories: P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: 8-carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3H)-one, 3,4-dihydro-3-methyl-4-oxoimidazo(5,1-d)-as-tetrazine-8-carboxamideIdoxuridine
go.drugbank.com/drugs/DB00249ApprovedWithdrawnAn analog of deoxyuridine that inhibits viral DNA synthesis. The drug is used as an antiviral agent.
Synonyms: 1-beta-D-2'-Deoxyribofuranosyl-5-iodouracil, 1-(2-Deoxy-beta-D-ribofuranosyl)-5-iodouracilProducts: Herplex DDisopyramide
go.drugbank.com/drugs/DB00280ApprovedInvestigationalA class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar
Categories: Antiarrhythmics, Class IaProducts: Rythmodan-LA, Rythmodan-LA 250mgLevothyroxine
go.drugbank.com/drugs/DB00451ApprovedInvestigational[F4633] Also known as L-thyroxine or the brand name product Synthroid, levothyroxine is used primarily to treat hypothyroidism, a condition where the thyroid gland is no longer able to produce sufficient … Levothyroxine is a synthetically produced form of thyroxine, a major endogenous hormone secreted by the thyroid gland.
Categories: UGT1A1 Substrates with a Narrow Therapeutic IndexProducts: L THYROXIN-NA-CT 50UG, L THYROXIN-NA ABZ 88UGZilucoplan
go.drugbank.com/drugs/DB15636ApprovedInvestigationalZilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. … It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein involved in the innate immune system to initiate inflammatory responses.