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Iodine
go.drugbank.com/drugs/DB05382ApprovedInvestigationalIodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.
Mixtures: ADDAMEL N, Ni-C-E-LE PlusPlumbagin
go.drugbank.com/drugs/DB17048InvestigationalIt has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways.[A253102]
Relutrigine
go.drugbank.com/drugs/DB21614InvestigationalRelutrigine is under investigation in clinical trial NCT07010471 (A Clinical Trial for Participants With DEE to Assess Efficacy, Safety, Tolerability, and PK of Relutrigine).
Gallium citrate Ga-67
go.drugbank.com/drugs/DB06784ApprovedGallium citrate Ga 67 is the citrate salt of the radioisotope gallium Ga 67. Although the mechanism is unknown, gallium Ga 67 concentrates in lysosomes and is bound to a soluble intracellular protein in certain viable primary and metasta...
Beremagene geperpavec
go.drugbank.com/drugs/DB17831ApprovedInvestigationalBeremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector therapy. Developed by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of wounds associated with ...
Isotretinoin
go.drugbank.com/drugs/DB00982ApprovedInvestigationalIsotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne.[Label] It was most widely marketed under the brand name Accutane, which has since been discontinued. Isotretinoin is associated with ma...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesEnlonstobart
go.drugbank.com/drugs/DB21890Investigational[A274486] It targets the programmed cell death protein 1 (PD-1), is being developed by the CSPC Pharmaceutical Group for the treatment of advanced cervical cancer and other solid tumours.
Inositol nicotinate
go.drugbank.com/drugs/DB08949ApprovedWithdrawnInositol nicotinate, also known as Inositol hexaniacinate/hexanicotinate or "no-flush niacin", is a niacin ester and vasodilator.
Cyclo(prolylglycyl)
go.drugbank.com/drugs/DB04541InvestigationalNA-831 (Traneurocin), is under investigation in two clinical trials: NCT03538522 (completed, for mild cognitive impairment and Alzheimer’s disease) and NCT04452565 (unknown status, combination therapy
Iopofosine I-131
go.drugbank.com/drugs/DB15244InvestigationalIopofosine I-131 (NM-404 I-131) is under investigation in clinical trial NCT01495663 (Dose Escalation Study of I-131-CLR1404 in Subjects With Cancer That Does Not Respond to Treatment or Has Returned).
Synonyms: 18-(P-(131I )-IODOPHENYL)OCTADECYL PHOSPHOCHOLINE, 18-(p-(131I)-iodophenyl)octadecyl phosphocholine