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Displaying results 1211 - 1220 of 7604 in total
  1. Drug

    Sulbactam

    go.drugbank.com/drugs/DB09324
    ApprovedInvestigational

    [L50131] When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydrolyzing β-lactams.[A263296]

    Mixtures: SULBACTER POWDER FOR SOLUTION FOR INJECTION or INFUSION 3g/vial, SULBACTER POWDER FOR SOLUTION FOR INJECTION or INFUSION 1.5g/vialCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  2. Drug

    Aminobenzoic acid

    go.drugbank.com/drugs/DB02362
    ApprovedWithdrawn

    The potassium salt is used therapeutically in fibrotic skin disorders.

    Categories: Protectives Against UV-Radiation for Topical Use, Protectives Against UV-Radiation
  3. Drug

    Trestolone

    go.drugbank.com/drugs/DB05830
    Investigational

    Trestolone (7α-methyl-19-nortestosterone) is a synthetic androgen developed by the Population Council as a potential candidate drug for use in hormonal male contraceptive methods.

    Categories: Hormonal Contraceptives for Systemic Use, Contraceptive Agents, MaleSynonyms: 19-Nor-methyltestosterone, 19-Nor-7alpha-methyltestosterone
  4. Drug

    Romidepsin

    go.drugbank.com/drugs/DB06176
    ApprovedInvestigational

    Romidepsin is a selective inhibitor of histone deacetylase, approved in the US in 2009 for the treatment of cutaneous T-cell lymphoma (CTCL) in patients who have received at least one prior systemic therapy

    Categories: Bile Salt Export Pump Inhibitors
  5. Drug

    D-alpha-Tocopherol acetate

    go.drugbank.com/drugs/DB14002
    ApprovedNutraceuticalVet approved

    At the moment however, there exists a lack of formal data and evidence to support any such additional indications for vitamin E use. … Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements.

    Mixtures: Poly-Vi-Flor, Poly-VI-florCategories: Compounds used in a research, industrial, or household setting
  6. Drug

    Difamilast

    go.drugbank.com/drugs/DB14987
    ApprovedInvestigational

    The drug is indicated for the topical treatment of mild to moderate atopic dermatitis in adults and pediatric patients 2 years of age and older [L55042]. It is approved in Japan and the United States.

  7. Drug

    Elexacaftor

    go.drugbank.com/drugs/DB15444
    ApprovedInvestigational

    [A187361] Elexacaftor, along with [VX-659], was designed to fill the need for an efficacious CF therapy for patients who are heterozygous for _F508del-CFTR_ and a gene that does not produce protein or … for the _F508del-CFTR_ gene - this represents approximately 70[A187373]-90%[A187361,A187355] of all CF patients.

  8. Drug

    Tramadol

    go.drugbank.com/drugs/DB00193
    ApprovedInvestigational

    [A182300] Similar to other opioid medications, tramadol poses a risk for development of tolerance, dependence and abuse. … Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain.

    Mixtures: DOR-2®Products: Tramadol Kalceks 50 mg/ml solution for injection/infusion, TRAMADOL 50 MG POR 1ML
  9. Drug

    Vilanterol

    go.drugbank.com/drugs/DB09082
    ApprovedInvestigational

    treatments of asthma in patients aged 18 years and older and 5 years and older respectively. … [L46876,L46881,L46886] Although all 3 products are approved for the maintenance treatment of chronic obstructive pulmonary disease (COPD), only TRELEGY ELLIPTA and BREO ELLIPTA are approved for maintenance

    Categories: Drugs for Obstructive Airway Diseases
  10. Drug

    Leucine

    go.drugbank.com/drugs/DB00149
    ApprovedInvestigationalNutraceutical

    An essential branched-chain amino acid important for hemoglobin formation.

    Mixtures: GLAMIN SOLUTION FOR INFUSION, KABIVEN EMULSION FOR INFUSION