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Naldemedine
go.drugbank.com/drugs/DB11691ApprovedInvestigationalNaldemedine was approved in 2017 in both the US and Japan for the treatment of Opioid-induced Constipation. … Naldemedine is an opioid receptor antagonist [FDA Label].
Glycopyrronium
go.drugbank.com/drugs/DB00986ApprovedInvestigationalVet approved[L33105] Glycopyrronium is commonly prescribed as a first line treatment for a wide variety indications and is considered to have a wider therapeutic window than [tiotropium]. … [A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the treatment of peptic ulcers.
Erythropoietin
go.drugbank.com/drugs/DB00016ApprovedInvestigationalEpoetin alfa (Epoge) was developed by Amgen Inc. in 1983 as the first rhEPO commercialized in the United States, followed by other alfa and beta formulations. … Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells.
Products: AIMAPEX 4000 IU/ML IN PREFILLED SYRINGE, HEMA-PLUS 1000 IU IN 0.25 ML PREFILLED SYRINGECarisoprodol
go.drugbank.com/drugs/DB00395ApprovedIn January 2012, this drug was classified as a Schedule IV substance under the controlled substances act in several US states due to alarming rates of abuse [A176062, A176077] despite having a low potential … This drug is available by itself in an oral tablet or combined with aspirin, or in a fixed-dose combination with both aspirin and codeine [FDA label, F4060, F4069].
Synonyms: N-isopropy-2-methyl-2-propyl-1,3-propanediol dicarbamateEstradiol valerate
go.drugbank.com/drugs/DB13956ApprovedInvestigationalVet approveddue to menopause, for the treatment of hypoestrogenism due to hypogonadism, castration or primary ovarian failure, and for the treatment of advanced androgen-dependent carcinoma of the prostate (for palliation … in potency and in estrogenic effects.
Mixtures: CYCLO PROGYNOVA N 2MG/0.15, CYCLO PROGYNOVA N 2MG/0.15Meradimate
go.drugbank.com/drugs/DB11096ApprovedMeradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different products as a UV filter. … [T200] It is currently required to be named as meradimate in all FDA approved OTC products. Meradimate is approved by the FDA and Health Canada to be used as an ingredient in sunblocking products.
Mixtures: SPF 15 Spray-ON Sunscreen, SPF 30+ Spray-ON SunscreenSodium glycerophosphate
go.drugbank.com/drugs/DB09561ApprovedGlycerophosphate is hydrolyzed to inorganic phosphate and glycerol in the body [A32667]. The extent of this reaction is dependent on the activity of serum alkaline phosphatases.
Mixtures: POLİNUTHREE EN-550 ELEKTROLİTLİ AMİNOASİT ÇÖZELTİSİ, GLUKOZ ÇÖZELTİSİ, VE LİPİD EMÜLSİYONU, 1000 ML, POLİNUTHREE EN-550 ELEKTROLİTLİ AMİNOASİT ÇÖZELTİSİ, GLUKOZ ÇÖZELTİSİ, VE LİPİD EMÜLSİYONU, 1500 MLTrovafloxacin
go.drugbank.com/drugs/DB00685ApprovedWithdrawnDue to its hepatotoxic potential, trovafloxacin was withdrawn from the market. … It exerts its antibacterial activity by inhibiting the uncoiling of supercoiled DNA in various bacteria by blocking the activity of DNA gyrase and topoisomerase IV.
Carbon monoxide
go.drugbank.com/drugs/DB11588ApprovedInvestigationalIt is toxic to hemoglobin utilizing animals (including humans), when encountered in concentrations above about 35 ppm, although it is also formed in normal animal metabolism in low quantities, and is thought … In New Zealand, the use of carbon monoxide in fish preparation has been banned, as it may mask the effects of food spoilage and bacterial growth [L2539].
Mixtures: Co-NE-O2-N2 Mixture, Lung Diffusion Test Mix No Ne CoPhosphatidyl serine
go.drugbank.com/drugs/DB00144ApprovedNutraceuticalPS has been investigated in a small number of double-blind placebo trials and has been shown to increase memory performance in the elderly. … PS has been shown to slow cognitive decline in animal models.
Mixtures: Enl