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Mitomycin
go.drugbank.com/drugs/DB00305ApprovedInvestigational[A193419] Mitomycin's cross-linking activity has resulted in its approval for the treatment of a variety of cancers - the most recent of which is an April 2020 approval for its use in low-grade Upper … Tract Urothelial Cancer (LG-UTUC)[L12867] - as well as adjunctly to _ab externo_ glaucoma surgeries.
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingSynonyms: Mito-C, Mitocin-CTolcapone
go.drugbank.com/drugs/DB00323ApprovedInvestigationalWithdrawnIt is a yellow, odorless, non-hygroscopic, crystalline compound. Tolcapone is associated with a risk of hepatotoxicity. … Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication.
Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme InhibitorsSynonyms: 3,4-dihydroxy-4'-methyl-5-nitrobenzophenone, 3,4-dihydroxy-5-nitro-4'-methylbenzophenoneCalcimycin
go.drugbank.com/drugs/DB19408InvestigationalPrimarily used as a biochemical tool for studying divalent cations in biological systems, Calcimycin also exhibits antibiotic activity against gram-positive bacteria and fungi. … Calcimycin is an ionophore and polyether antibiotic derived from Streptomyces chartreusensis.
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 2-RingSynonyms: Antibiotic a-23187, 4-benzoxazolecarboxylic acid, 5-(methylamino)-2-(((2r,3r,6s,8s,9r,11r)-3,9,11-trimethyl-8-((1s)-1-methyl-2-oxo-2-(1h-pyrrol-2-yl)ethyl)-1,7-dioxaspiro(5.5)undec-2-yl)methyl)-Benzocaine
go.drugbank.com/drugs/DB01086ApprovedInvestigationalBenzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.
Mixtures: EMEDUR 100 MG/20 MG SUPOZİTUAR, 5 ADET, EMEDUR 200 MG SUPOZITUAR, 100 ADETCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesOctinoxate
go.drugbank.com/drugs/DB09496ApprovedInvestigationalOctinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage. … It was originally developed in 1950's as an organic UV-B filter that absorbs UV-B rays from sun.
Mixtures: A M Stimulus Complex SPF 25, Advanced Marine Biology Day SPF 20 La Prairie Group AGCategories: Compounds used in a research, industrial, or household settingValaciclovir
go.drugbank.com/drugs/DB00577ApprovedInvestigationalGenital herpes is a frequently diagnosed sexually transmitted disease which currently affects more than 400 million individuals worldwide. … It is a member of the purine (guanine) nucleoside analog drug class [F3949]. This class of drugs forms an important part of hepatitis, HIV, and cytomegalovirus drug regimens [A175900].
Categories: Heterocyclic Compounds, 2-RingSynonyms: L-Valine, 2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)ethyl ester, L-Valine ester with 9-((2-hydroxyethoxy)methyl)guanineMagaldrate
go.drugbank.com/drugs/DB08938ApprovedInvestigationalWithdrawnMagaldrate is an antacid drug used for the treatment of esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux. Magaldrate has been discontinued in the US market.
International brands: Almagel T, Almadrat TMixtures: M A L D I M, ASIDOPAN PLUS 200 ML SUSPANSIYONRivastigmine
go.drugbank.com/drugs/DB00989ApprovedInvestigationalRivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase. … Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type.
Categories: Compounds used in a research, industrial, or household settingSynonyms: m-((S)-1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamate, (S)-3-(1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamateCarteolol
go.drugbank.com/drugs/DB00521ApprovedA beta-adrenergic antagonist used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and an antiglaucoma agent.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: CARTEOL LP %1 UZUN ETKILI GOZ DAMLASI, 3 ML, CARTEOL LP %2 UZUN ETKILI GOZ DAMLASI, 3 MLKetamine
go.drugbank.com/drugs/DB01221ApprovedInvestigationalVet approvedKetamine is an NMDA receptor antagonist with a potent anesthetic effect.[A31869] It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. … It was FDA approved in 1970, and from there, it has been used as an anesthetic for children or patients undergoing minor surgeries but mainly for veterinary purposes.[L1332]
Categories: Cytochrome P-450 Substrates, N-Methylaspartate, agonistsSynonyms: 2-(2-Chloro-phenyl)-2-methylamino-cyclohexanone, 2-(methylamino)-2-(2-chlorophenyl)cyclohexanone