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Thrombin alfa
go.drugbank.com/drugs/DB11572Approvedapproved by certain organizations like the European Medicines Agency [L2079]. … The cell line used to manufacture Thrombin Alfa has been tested and shown to be free of known infectious agents.
Cresol
go.drugbank.com/drugs/DB11143ApprovedIngestion of cresol induces toxicity in humans and can lead to burning of the mouth and throat, abdominal pain, and/or vomiting. … At concentrations normally found in the environment however, cresols do not pose any significant risk for the general population.
Naratriptan
go.drugbank.com/drugs/DB00952ApprovedNaratriptan is a triptan drug that is selective for the 5-hydroxytryptamine1 receptor subtype. It is typically used for the treatment of migraine headaches.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSodium hydroxide
go.drugbank.com/drugs/DB11151ApprovedAccording to the the FDA, sodium hydroxide is considered a direct food recognized as safe, where it serves as a pH control agent and follows good manufacturing guidelines [L1967]. … The use of this compound has been shown to effectively reduce prion levels in an in vitro inactivation assay [A32334].
Mixtures: AMINOPLASMAL® 10% E, AMINOPLASMAL® 10% ETannic acid
go.drugbank.com/drugs/DB09372ApprovedInvestigationalIt is a type of the commercially available tannins. It acts as a weak acid. … In the old days it was used as antidote against different poisons. Nowadays, tannic acid is applied topically for the treatment of cold sores, diaper rash, fever blisters and poison ivy.
Mixtures: Extrait De FraisesGlucarpidase
go.drugbank.com/drugs/DB08898ApprovedInvestigational[L39855] Glucarpidase was first approved by the FDA in January 2012,[A7476] followed by the European Commission's approval in January 2022.[L39865] It is marketed as VORAXAZE. … In 1983, the gene for carboxypeptidase G2, or glucarpidase, was derived from _Pseudomonas_ sp. strain RS-16 to be cloned into _Escherichia coli_, allowing the enzyme to be produced in sufficient quantities
Fostemsavir
go.drugbank.com/drugs/DB11796ApprovedInvestigationalprevents the first step in the HIV-1 viral lifecycle. … [L14867] It binds to and inhibits the activity of gp120, a subunit within the HIV-1 gp160 envelope glycoprotein that facilitates the attachment of HIV-1 to host cell CD4 receptors - in doing so, temsavir
Baclofen
go.drugbank.com/drugs/DB00181ApprovedInvestigationalAlthough originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. … [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the FDA in 1977.
Products: BACLENO® 10MG/5ML SOLUCIÓN DE PERFUSIÓNTromethamine
go.drugbank.com/drugs/DB03754ApprovedInvestigational(From Merck, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p1424) … It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used
Categories: Solutions Affecting the Electrolyte BalanceLeucovorin
go.drugbank.com/drugs/DB00650ApprovedInvestigational[A275451] It is primarily indicated for "leucovorin rescue" to diminish the hematologic and mucosal toxicity of high-dose methotrexate therapy in osteosarcoma and to treat inadvertent overdoses of folic … [L56091, L56092] Additionally, it is used in combination with 5-fluorouracil (5-FU) to enhance therapeutic efficacy in the palliative treatment of advanced colorectal cancer and to treat megaloblastic
Products: FOLINATO DE CALCIO 50 MG, CALCIUMFOLINAT HE 100MG/10