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Uridine triacetate
go.drugbank.com/drugs/DB09144ApprovedWhen used for the treatment or prevention of toxicity associated with fluorouracil and other antimetabolites, uridine triacetate is utilized for its ability to compete with 5-fluorouracil (5-FU) metabolites … Like many other neoplastic agents, these side effects limit the doses of 5-FU that can be administered, which also affects the efficacy for treatment.
Synonyms: Tri-O-acetyluridine, 2',3',5'-tri-O-acetyluridineTagraxofusp
go.drugbank.com/drugs/DB14731ApprovedInvestigationalIt is a fusion protein composed of a human interleukin-3 (IL-3) that is genetically fused to the catalytic and translocation domains of truncated diphtheria toxin (DT) produced in _Escherichia coli_. … [A253762] It was also approved by the European Commission on January 7, 2021.[L43712]
Cinnarizine
go.drugbank.com/drugs/DB00568ApprovedInvestigationalCinnarizine could be also viewed as a nootropic drug because of its vasorelaxating abilities (due to calcium channel blockage), which happen mostly in brain. … Cinnarizine is a specific calcium channel blocker that primarily works on the central vestibular system to interfere with the signal transmission between vestibular apparatus of the inner ear and the vomiting
Products: CN - 25Indigotindisulfonic acid
go.drugbank.com/drugs/DB11577ApprovedInvestigationalIndigotindisulfonic acid is a blue-colored dye with a variety of uses. … This compound is an acid-base indicator and is used in the production of food colorants and pH tests.
Categories: Compounds used in a research, industrial, or household settingPyridostigmine
go.drugbank.com/drugs/DB00545ApprovedInvestigational[A231009, A231014, L32413, L32418] Pyridostigmine was granted initial FDA approval on April 6, 1955, as an oral tablet. … [A231004] Acetylcholinesterase inhibitors have been the symptomatic treatment of choice in myasthenia gravis since the 1930s with the early use of [physostigmine] and [neostigmine].
International brands: Kalymin NAmiodarone
go.drugbank.com/drugs/DB01118ApprovedInvestigationalAmiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. … Because of its ability to cause serious toxicity and possibly death, amiodarone use should be reserved for its approved indications, according to prescribing information.[L3561,L11265,L11286]
Categories: Metabolic Side Effects of Drugs and SubstancesSynonyms: 2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuranPolysorbate 80
go.drugbank.com/drugs/DB11063ApprovedInvestigationalPolysorbate, a substance formulated by the reaction of sorbitan fatty acid ester (a nonionic surfactant) with ethylene oxide, is used in many foreign countries, including the U.S. and the EU, where it … Polysorbate 80 is an excipient that is used to stabilize aqueous formulations of medications for parenteral administration or vaccinations.
Mixtures: ENDURA® UDCategories: Compounds used in a research, industrial, or household settingThiethylperazine
go.drugbank.com/drugs/DB00372ApprovedInvestigationalWithdrawnThis piperazine phenothiazine does not prevent vertigo or motion sickness. (From AMA Drug Evaluations Annual, 1994, p457) … A dopamine antagonist that is particularly useful in treating the nausea and vomiting associated with anesthesia, mildly emetic cancer chemotherapy agents, radiation therapy, and toxins.
Categories: Dopamine D2 Receptor AntagonistsColfosceril palmitate
go.drugbank.com/drugs/DB09114ApprovedWithdrawn[A31510] It was part of the first generation of commercially available artificial surfactants.[T70] It was developed by Burroughs Wellcome and it was FDA approved on August 6, 1990. … [L1109] Nowadays colfosceril palmitate is under the state of canceled post-marketing.
Synonyms: Palmitate de colfosceril, Palmitato de colfosceriloAlprazolam
go.drugbank.com/drugs/DB00404ApprovedIllicitInvestigational[A18125] Alprazolam was given FDA approval on October 16, 1981.[L6148] … [A18125] Alprazolam has been mixed with alcohol as a drug of abuse to potentiate the sedative effects of the drug which may lead to coma and death.
Mixtures: NEUPAX DUO-SProducts: Nu-alpraz Tab 0.5mg, Nu-alpraz Tab 0.25mg