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Displaying results 1241 - 1250 of 10000 in total
  1. Drug

    Azilsartan medoxomil

    go.drugbank.com/drugs/DB08822
    ApprovedInvestigational

    enzyme (ACE) inhibitors that are also used as first-line treatment for hypertension. … It is also available in a combination product with [chlorthalidone].

    Categories: Angiotensin II receptor antagonists, Angiotensin II Type 1 Receptor Blockers
  2. Indication

    Barrett's Esophagus

    go.drugbank.com/conditions/DBCOND0030309
    Drugs: Porfimer sodium
    Synonyms: Columnar-lined esophagus, Columnar-lined oesophagus
  3. Drug

    Zinc acetate

    go.drugbank.com/drugs/DB14487
    ApprovedInvestigational

    Synonyms: Zinc(II) acetateMixtures: IC Ivy Relief, NUTRIFLEX LIPID PERI INFUZYONLUK IV EMULSIYON, 2500 ML
  4. Drug

    Somatrem

    go.drugbank.com/drugs/DB09098
    ApprovedWithdrawn

    continues to be mired in persistent bioethical debate [A32292]. … Despite the ability of almost all contemporary recombinant growth hormones to cause definite and demonstrable increases in growth rate in patients who are administered the drug, the use of these agents

    Mixtures: Protropin Inj Pws 10mg/vial, Protropin - Kit Im Sc 10mg/vial
  5. Drug

    Trifluridine

    go.drugbank.com/drugs/DB00432
    ApprovedInvestigational

    Trifluridine is a fluorinated pyrimidine nucleoside that is structurally related to [idoxuridine] [A35271]. … It is an active antiviral agent in ophthalmic solutions used mainly in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to herpes simplex virus.

  6. Drug

    Choline

    go.drugbank.com/drugs/DB00122
    ApprovedInvestigationalNutraceutical

    It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. … A basic constituent of lecithin that is found in many plants and animal organs.

    Mixtures: L Fac Tab, Multi II IV Vi TabSynonyms: Choline ion, N,N,N-trimethylethanol-ammonium
  7. Drug

    Potassium

    go.drugbank.com/drugs/DB14500
    ApprovedInvestigational

    Potassium is often a key ingredient for intravenous fluids, given to patients in clinical settings for rehydration, nutrition, and replenishment of electrolytes. … Potassium is an essential nutrient, like [Calcium] and [Magnesium]. It was identified as a shortfall nutrient by the 2015-2020 Advisory Committee of Dietary Guidelines for Americans.

    Mixtures: Formula F L W, Formula F L WProducts: Port A Mins Super Potassium 99
  8. Drug

    Bosutinib

    go.drugbank.com/drugs/DB06616
    ApprovedInvestigational

    Philadelphia chromosome is a hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR-ABL fusion protein. … [A6902,A261796,A261801] The first BCR-ABL inhibitor, [imatinib], was introduced over a decade ago as a breakthrough in CML management; however, emerging resistance to [imatinib] poses challenges in achieving

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index
  9. Drug

    Lifitegrast

    go.drugbank.com/drugs/DB11611
    ApprovedInvestigational

    It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist that was discovered through the rational design process. … The ophthalmic solution was approved in July, 2016 under the trade name Xiidra.

    Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Enalapril

    go.drugbank.com/drugs/DB00584
    ApprovedInvestigationalVet approved

    It is also found in a combination product containing [hydrochlorothiazide] that is used for the management of hypertension. … and renal reabsorption of sodium ions in the kidneys.

    Synonyms: (S)-1-(N-(1-(ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-L-proline, 1-(N-((S)-1-carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1'-ethyl esterInternational brands: Vasotec IV