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VPM1002
go.drugbank.com/drugs/DB15801InvestigationalBy reducing urease C, phagosome acidification can occur, promoting phagolysosome fusion while also providing the optimal low pH for listeriolysin O stability. … Because Hly is only active at an acidic pH, similar to listeriolysin O, the deletion of urease C was also beneficial for Hly to have optimal bioactivity in the phagosome.
Dimethyl sulfone
go.drugbank.com/drugs/DB14090InvestigationalMixtures: Sul Vital Cool, Dpheal Sul 16 CoolProducts: Sul Vital Hot, Dpheal Sul 16 HotMeradimate
go.drugbank.com/drugs/DB11096ApprovedMeradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different products as a UV filter. It is currently required to be named as meradimate in all FDA approved OTC products. Meradimate is approved ...
Mixtures: BIOCORNEUM PLUS BROAD SPECTRUM SPF 30 ADVANCED SCAR TREATMENT gelAbacavir
go.drugbank.com/drugs/DB01048ApprovedInvestigationalAbacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclop...
Mixtures: Triumeq PD, ABACAVIR E LAMIVUDINA DOC GENERICIIron
go.drugbank.com/drugs/DB01592ApprovedInvestigationalA metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. Its chief functions are in the transp...
Mixtures: Ganilia Soft GelInsulin lispro
go.drugbank.com/drugs/DB00046ApprovedInvestigationalMarketed as the brand name product Humalog, insulin lispro begins to exert its effects within 15 minutes of subcutaneous administration, while peak levels occur 30 to 90 minutes after administration.
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersSimeprevir
go.drugbank.com/drugs/DB06290ApprovedWithdrawnSimeprevir was approved by the FDA in November 2014 and is marketed under the brand name Olysio as oral tablets.
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitors