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Artenimol
go.drugbank.com/drugs/DB11638ApprovedInvestigationalArtemisinin combination therapy is highly effective against malaria and stongly recommended by the World Health Organization [L1156]. … It was first authorized for market by the European Medicines Agency in October 2011 in combination with [DB13941] as the product Eurartesim.
DL-dimyristoylphosphatidylglycerol
go.drugbank.com/drugs/DB11284ApprovedDL-dimyristoylphosphatidylglycerol is a phospholipid used in commercially available pharmaceutical preparations to solubilize drugs for injection.
Azilsartan medoxomil
go.drugbank.com/drugs/DB08822ApprovedInvestigationalAlthough there is no clinical significance yet determined, azilsartan medoxomil may have potential off-label uses in patients with a history of myocardial infarction or heart failure.[A232863] … Azilsartan medoxomil is a relatively recently-developed antihypertensive drug that was first approved by the FDA in February 2011.
Tolazoline
go.drugbank.com/drugs/DB00797ApprovedVet approvedWithdrawnTolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear.
Colchicine
go.drugbank.com/drugs/DB01394ApprovedInvestigational[A183611] Its use was first approved by the FDA in 1961.
Categories: Preparations With No Effect on Uric Acid MetabolismTizanidine
go.drugbank.com/drugs/DB00697ApprovedInvestigationalIt may also be caused by musculoskeletal injury [A177583]. Regardless of the cause, muscle spasticity can be an extremely painful and debilitating condition. … Initially approved by the FDA in 1996, tizanidine is an Alpha-2 adrenergic receptor agonist reducing spasticity by the presynaptic inhibition of excitatory neurotransmitters that cause firing of neurons
Mixtures: MYOS -NOR F TABLETASGallium nitrate
go.drugbank.com/drugs/DB05260ApprovedInvestigationalGallium nitrate is a nitrate salt of DB14524, a heavy metal that has been used as a diagnostic agent. Gallium nitrate is reported to possess antiresorptive and hypocalcemic effects on bone. GANITE, a product of gallium nitrate previously...
Estradiol
go.drugbank.com/drugs/DB00783ApprovedInvestigationalVet approvedSome available forms of estradiol include oral tablets, injections, vaginal rings, transdermal patches, sprays, gels, and creams. … Because it has a low oral bioavailability on its own, estradiol is commonly formulated with an ester side-chain.
Mixtures: KLIOGEST N, KLIOGEST NIsocarboxazid
go.drugbank.com/drugs/DB01247Approved[T115] It was first introduced by Roche pharmaceuticals, further developed by Validus pharms Inc and first FDA approved as a prescription drug on July 1st, 1959.
Categories: Monoamine Oxidase Inhibitors, Non-SelectiveAntihemophilic factor human
go.drugbank.com/drugs/DB13192ApprovedInvestigationalFactor VIII, but does not contain the B-domain, which has no known biological function and [DB11607], which is a fully recombinant factor VIII-Fc fusion protein which has an extended half-life compared … The complex was developed by CSL Behring or Baxter Healthcare Corporation and approved in the 90s.