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Displaying results 121 - 130 of 144663 in total
  1. Drug

    Ximelagatran

    go.drugbank.com/drugs/DB04898
    ApprovedWithdrawn

    Ximelagatran is an anticoagulant intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and monitoring issues associated with the former. … In 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and to discontinue its distribution in countries

    Categories: Blood and Blood Forming OrgansSynonyms: ethyl 2-[[(1R)-1-cyclohexyl-2- [(2S)-2-[[4-(N'-hydroxycarbamimidoyl) phenyl]methylcarbamoyl]azetidin-1-yl]- 2-oxo-ethyl]amino]acetate
  2. Drug

    Ethyl Oxo(Piperidin-1-Yl)Acetate

    go.drugbank.com/drugs/DB02419
    Experimental

    Synonyms: Ethyl Oxo(Piperidin-1-Yl)Acetate
  3. Drug

    Pam2csk4

    go.drugbank.com/drugs/DB16474
    Investigational

    Synonyms: Pam2CSK4 acetateCategories: Amino Acids, Peptides, and Proteins
  4. Drug

    TAK-475

    go.drugbank.com/drugs/DB05317
    Investigational

    TAK-475 is a "squalene synthase inhibitor", a type of cholesterol-lowering drug that has not yet been brought to market.

    Synonyms: Lapaquistat Acetate
  5. Drug

    Ganirelix

    go.drugbank.com/drugs/DB06785
    ApprovedInvestigational

    Ganirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist. Derived from endogenous GnRH, ganirelix has amino acid substitutions. … [L43045] The first case of pregnancy achieved after the use of ganirelix in an assisted reproduction program was reported in 1998.[A252195] Ganirelix was first approved by the FDA on July 29, 1999.

    Salts: Ganirelix acetateCategories: Pituitary and Hypothalamic Hormones and Analogues, Sex Hormones and Insulins
  6. Drug

    Teriparatide

    go.drugbank.com/drugs/DB06285
    ApprovedInvestigational

    [A251395] Teriparatide is used in the treatment of osteoporosis in men and women.[L42590, L42595] … Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent.[A251395] It is made up of the first amino(N)-terminal 34 amino acids of the human PTH.

    Salts: Teriparatide acetateCategories: Sex Hormones and Insulins, Amino Acids, Peptides, and Proteins
  7. Drug

    Aceburic acid

    go.drugbank.com/drugs/DB20668
    Experimental

    Aceburic acid is a small molecule drug. Aceburic acid has a monoisotopic molecular weight of 146.06 Da.

    Synonyms: 4-hydroxybutyric acid acetate
  8. Drug

    Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase

    go.drugbank.com/drugs/DB18681
    Experimental

    Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase is an investigational lentiviral gene therapy. … It comprises autologous CD34+ hematopoietic stem and progenitor cells (HSPCs) that had been genetically modified ex vivo with EFS-ADA LV.

    Synonyms: Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase
  9. Drug

    Desmopressin

    go.drugbank.com/drugs/DB00035
    ApprovedInvestigational

    First synthesized in the 1960s, desmopressin has remained a gold-standard therapy for water balance disorders due to its safety and long duration of action compared to natural AVP [A31661, A275461]. … approved a new low-dose sublingual film formulation specifically for the treatment of nocturia in patients at high risk for fluid overload, utilizing a specialized delivery system to minimize systemic water

    Salts: Desmopressin acetate, Desmopressin acetate anhydrousCategories: Pituitary and Hypothalamic Hormones and Analogues, Sex Hormones and Insulins
  10. Drug

    Lanreotide

    go.drugbank.com/drugs/DB06791
    ApprovedInvestigational

    Lanreotide is manufactured by the company, _Ipsen Pharmaceuticals_ as lanreotide acetate, and marketed as _Somatuline_. … It is approved in several countries worldwide, including the United Kingdom, Australia, and Canada. Lanreotide was first approved for use in the United States by the FDA on August 30, 2007.

    Salts: Lanreotide acetateCategories: Pituitary and Hypothalamic Hormones and Analogues, Sex Hormones and Insulins