Pam2csk4

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DB16474InvestigationalSmall molecule

Pam2csk4: Overview.

Mechanism: Pam2 is a synthetic lipopeptide which acts as an agonist at TLR2 and TLR6. Actions at these receptors suggest that Pam2 has potential antiviral properties.
Curator reviewed
Formula / weight: C₆₅H₁₂₆N₁₀O₁₂S · 1271.84 g/mol (avg)
Also known as: Pam2 · Pam2CSK4 acetate
Code names: CBLB 601

Resolves to

Compound

UNIIL33ZW7BO91CAS574741-81-4ChEBI46889

Structure

InChIKeyLJUIOEFZFQRWJG-KKIBDXJDSA-NSMILES

CCCCCCCCCCCCCCCC(=O)OCC(CSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O)OC(=O)CCCCCCCCCCCCCCC

Targets

Q9Y2C9TLR6O60603TLR2

What you can answer from here — as of February 04, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with Pam2csk4, and which of those have an active Phase 3 trial?

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