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Mycophenolic acid
go.drugbank.com/drugs/DB01024ApprovedInvestigational[A249175] This regimen can be used in place of the older anti-proliferative [azathioprine] due to its stronger immunosuppressive potency. … [A249180,A249185] Mycophenolic acid is available as enteric-coated tablets of delayed-release, in an effort to improve upper gastrointestinal adverse events by delaying mycophenolic acid release until
Categories: Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: (e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acidIbandronate
go.drugbank.com/drugs/DB00710ApprovedInvestigational[L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs.[A203138] Ibandronate was granted FDA approval on 16 May 2003.[L13805] … Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to [zoledronic acid], [minodronic acid], and [risedronic acid].
Mixtures: IBONE D®, IBONE D 30000Products: BONDRONAT 6MG KON HER INF, BONDRONAT® CONCENTRADO DE SOLUCION PARA INFUSION 6 MG/6ML.Teriflunomide
go.drugbank.com/drugs/DB08880ApprovedInvestigationalTeriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. … The FDA label states an important warning about the risk of hepatoxicity and teratogenicity for patients using teriflunomide.
Synonyms: (Z)-2-cyano-alpha,alpha,alpha-trifluoro-3-hydroxy-p-crotonotoluidideCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersCalcium glucoheptonate
go.drugbank.com/drugs/DB00326ApprovedInvestigationalThey are used to prevent or treat several conditions that may cause hypocalcemia (not enough calcium in the blood). The body needs calcium to make strong bones. … Calcium supplements such as calcium gluceptate are taken by individuals who are unable to get enough calcium in their regular diet or who have a need for more calcium.
Synonyms: Glucoheptonate de calcium, Calcium glucoheptonate (1:2)Products: Sirop De Calcium 625mg/5mlLactobacillus acidophilus
go.drugbank.com/drugs/DB15823ApprovedInvestigationalMixtures: RisaQuad-2, GYNOFLOR 50 MG/0.03 MG VAJİNAL TABLET, 6 ADETProducts: Acidocore Max, Flora QHypochlorite
go.drugbank.com/drugs/DB11123ApprovedInvestigationalHypochlorite is an ion composed of chlorine and oxygen with the chemical formula ClO−. … Hypochlorite is often used as a chemical reagent for chlorination and oxidation reactions.
Mixtures: K-100, K-100Categories: Compounds used in a research, industrial, or household settingFarnesol
go.drugbank.com/drugs/DB02509InvestigationalIt is an intermediate step in the biological synthesis of cholesterol from mevalonic acid in vertebrates. It has a delicate odor and is used in perfumery. … A colorless liquid extracted from oils of plants such as citronella, neroli, cyclamen, and tuberose.
Products: Deo Pedico Above Neymar Jr MenEphedra sinica root
go.drugbank.com/drugs/DB01363ApprovedNutraceuticalEphedra is an alkaloid chemical compound traditionally obtained from the plant _Ephedra sinica_. … The sale of ephedra-containing supplements intended to increase muscle weight or promote weight loss was banned in the United States in 2004 due to the risk for adverse effects and a lack of evidence for
Mixtures: Dr. Miller's Formula No. 1Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Adrenergic alpha-2 Receptor AgonistsCapivasertib
go.drugbank.com/drugs/DB12218ApprovedInvestigationalTherefore, targeting the PIK3/AKT pathway presents a promising approach for the treatment of breast cancer, leading to the development of capivasertib, a pan-AKT kinase inhibitor. … [A262021] The PIK3/AKT pathway is one of the most commonly activated pathways in breast cancer, mainly through the constitutively active mutation in AKT1, loss of function mutation in PTEN, a negative
Categories: MATE 1 Inhibitors, MATE 2 InhibitorsAfatinib
go.drugbank.com/drugs/DB08916ApprovedInvestigationalby an FDA-approved test [L2939]. … Afatinib is a 4-anilinoquinazoline tyrosine kinase inhibitor in the form of a dimaleate salt available as Boehringer Ingelheim's brand name Gilotrif [FDA Label].
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Mar-afatinib, GIOTRIF® 30 MG