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Displaying results 121 - 130 of 1809 in total
  1. Drug

    Aluminum sesquichlorohydrate

    go.drugbank.com/drugs/DB11108
    Approved

    Aluminum sesquichlorohydrate is an aluminum salt used as an antiperspirant agent, cosmetic astringent and deodorant agent. It works by physically blocking eccrine sweat gland ducts .

    Products: Antiperspirant Above Dolce Vita
  2. Pathway

    Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin

    smpdb.ca/view/SMP0000354
    Signaling

    The receptor is a G-protein coupled receptor, upon its binding it activates G proteins causing the activation of adenylyl cyclase and production of cAMP messenger molecules. cAMP activates PKA (protein … Prostacyclin binding to its receptor increases vasodilation and decreases platelet aggregation.

    Drugs: ATP · Calcium · Magnesium cation · Cyclic adenosine monophosphate · Pyrophosphoric acid
    Enzymes: Prostacyclin receptor
  3. Pathway

    Trimebutine M3 Receptor Intestine Relaxation Action Pathway

    smpdb.ca/view/SMP0126338
    Drug action

    Trimebutine is a spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and treatment of postoperative paralytic ileus following abdominal surgery. Trimebutine is a spasmolytic agent that regulates intesti...

    Drugs: ATP · Nitric Oxide · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate +3 more
    Enzymes: Mu-type opioid receptor, Muscarinic acetylcholine receptor M3
  4. Drug

    Allantoin

    go.drugbank.com/drugs/DB11100
    ApprovedInvestigational

    Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets [FDA Label]. In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. During exercise, th...

    Mixtures: Essential Solution Vita A Mask Sheet, Essential Solution Vita C Mask SheetProducts: Easydew Daily 2 Step Vita Toning Mask
  5. Target

    Pregnancy zone protein

    go.drugbank.com/bio_entities/BE0009089
    TargetHumans

    Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves...

    Polypeptides: Pregnancy zone protein
  6. Drug

    Octinoxate

    go.drugbank.com/drugs/DB09496
    ApprovedInvestigational

    Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage. It was originally developed in 1950's as an organic UV-B filter that absorbs UV-B rays from sun. It is often com...

    Mixtures: Kara Vita SPF 29, Kara Vita SPF 30Products: Vita K, Esika Hd Color High Definition Color SPF 20 (hd Rosa Viva) - Pink
  7. Drug

    WU-CART-007

    go.drugbank.com/drugs/DB18617
    Investigational

    WU-CART-007 consists of allogeneic, fratricide-resistant genetically modified T cells transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human CD7.

    Synonyms: an allogeneic, fratricide-resistant genetically modified T cell transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human CD7
  8. Drug

    Bilberry

    go.drugbank.com/drugs/DB14235
    ApprovedWithdrawn

    Synonyms: Myrtilli fructus recens (vaccinium myrtillus l.)
  9. Pathway

    Intracellular Signalling Through Adenosine Receptor A2b and Adenosine

    smpdb.ca/view/SMP0000321
    Signaling

    The adenosine receptor A2b activates G(s) proteins which lead to the activation of adenylyl cyclase which produces the secondary messenger cAMP. cAMP activates PKA (protein kinase A) which phosphorylates

    Drugs: ATP · Adenosine · Magnesium cation · Zinc · Cyclic adenosine monophosphate · Pyrophosphoric acid
    Enzymes: Adenosine receptor A2b
  10. Drug

    Navepegritide

    go.drugbank.com/drugs/DB17824
    ApprovedInvestigational

    [L56058,A275435] Navepegritide is a prodrug of active C-type natriuretic peptide (CNP) consisting of a CNP moiety transiently conjugated to two methoxy polyethylene glycol (mPEG) moieties via a proprietary … [L56065] Navepegritide was approved by the US FDA in February 2026 for use in patients 2 years of age and older with achondroplasia with open epiphyses.[L56058,L56065]