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Lynestrenol
go.drugbank.com/drugs/DB12474ApprovedWithdrawnLynestrenol is a progestin and prodrug of norethisterone.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Orgametril - TablettenMethotrexate
go.drugbank.com/drugs/DB00563ApprovedInvestigationalMethotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate i...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: Ebetrexat 10 mg - Tabletten, Ebetrexat 5 mg - TablettenDexamethasone
go.drugbank.com/drugs/DB01234ApprovedInvestigationalVet approvedDexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other condit...
Mixtures: Dex-Moxi PF, DexMoxiKetor PFCategories: P-glycoprotein inducers, P-glycoprotein inhibitorsAnagrelide
go.drugbank.com/drugs/DB00261ApprovedInvestigationalAnagrelide is a platelet-reducing agent used to lower dangerously elevated platelet levels (i.e. to treat thrombocythemia) in patients with myeloproliferative neoplasms. It is an oral imidazoquinazoline that was first approved for use in...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: Anagrelid Nordic 1 mg Tabletten, Anagrelid Nordic 0,5 mg TablettenTioguanine
go.drugbank.com/drugs/DB00352ApprovedInvestigationalAn antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
Products: Thioguanin "Aspen" 40 mg TablettenPiretanide
go.drugbank.com/drugs/DB02925ApprovedPiretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine residues in an aromatic nucleus in the presenc...
Mixtures: RAMIPRIL HEXAL PL PIR5/6MG, RAMIPRIL HEXAL PL PIR5/6MGProducts: PIRETANID AL 6MG TABLETTENPioglitazone
go.drugbank.com/drugs/DB01132ApprovedInvestigationalPioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications to manage type 2 diabetes mellitus. It is administered as a racemic mixture, though there is no pharmacologic difference betwee...
Mixtures: INCRESINA PCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesProcyclidine
go.drugbank.com/drugs/DB00387ApprovedA muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism.
Products: KEMADRIN TablettenPhenylephrine
go.drugbank.com/drugs/DB00388ApprovedInvestigationalPhenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension, dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Pheny...
Mixtures: Dover Coldonyl, Quality Choice Mucus Relief PE PECategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersLovastatin
go.drugbank.com/drugs/DB00227ApprovedInvestigationalLovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite derived synthetically from a fermentation product of Aspergillus terreus. Originally named Mevinolin, lovastatin belongs to the stat...
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsProducts: LOVABETA 10MG TABLETTEN, LOVABETA 20MG TABLETTEN