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Displaying results 121 - 130 of 2454 in total
  1. Drug

    Gepirone

    go.drugbank.com/drugs/DB12184
    Approved

    Gepirone, an azapirone, is a pharmacologic analog of [buspirone] that acts selectively on the pre- and post-synaptic 5HT<sub>1A</sub> receptors.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  2. Drug

    Zalospirone

    go.drugbank.com/drugs/DB19481
    Experimental

    The usage of the INN stem '-pirone' in the name indicates that Zalospirone is a anxiolytic, buspirone derivative. Zalospirone has a monoisotopic molecular weight of 419.23 Da.

  3. Drug

    Revospirone

    go.drugbank.com/drugs/DB20158
    Experimental

    The usage of the INN stem '-pirone' in the name indicates that Revospirone is a anxiolytic, buspirone derivative. Revospirone has a monoisotopic molecular weight of 387.14 Da.

  4. Drug

    Umespirone

    go.drugbank.com/drugs/DB20674
    Experimental

    The usage of the INN stem '-pirone' in the name indicates that Umespirone is a anxiolytic, buspirone derivative. Umespirone has a monoisotopic molecular weight of 512.3 Da.

  5. Drug

    Alnespirone

    go.drugbank.com/drugs/DB19784
    Experimental

    The usage of the INN stem '-pirone' in the name indicates that Alnespirone is a anxiolytic, buspirone derivative. Alnespirone has a monoisotopic molecular weight of 442.28 Da.

  6. Drug

    Eptapirone

    go.drugbank.com/drugs/DB19836
    Experimental

    The usage of the INN stem '-pirone' in the name indicates that Eptapirone is a anxiolytic, buspirone derivative. Eptapirone has a monoisotopic molecular weight of 345.19 Da.

  7. Drug

    Pyridoxine

    go.drugbank.com/drugs/DB00165
    ApprovedInvestigationalNutraceuticalVet approved

    Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods. As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for nor...

    Mixtures: Virt-Pn, Virt-PN
  8. Drug

    Nicotinamide

    go.drugbank.com/drugs/DB02701
    ApprovedInvestigational

    An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent n...

    Mixtures: BOTA C Reset, Virt-PnCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Inhibitors
  9. Drug

    Nivolumab

    go.drugbank.com/drugs/DB09035
    ApprovedInvestigational

    Nivolumab is a fully human IgG4 antibody targeting the immune checkpoint programmed death receptor-1 (PD-1).

    Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors
  10. Drug

    Cosibelimab

    go.drugbank.com/drugs/DB15770
    ApprovedInvestigational

    Cosibelimab is a human IgG1 lambda monoclonal antibody directed against programmed death ligand-1 (PD-L1). … On December 13, 2024, cosibelimab was approved by the FDA for the treatment of metastatic or locally advanced cutaneous squamous cell carcinoma [L52690] as the first approved anti-PD-L1 therapy in the

    Synonyms: anti-Pd-l1 monoclonal antibody CK-301, IMMUNOGLOBULIN G1-LAMBDA, ANTI-(HOMO SAPIENS PROGRAMMED CELL DEATH 1 LIGAND 1 (PD-L1, CD274 ANTIGEN))HUMAN MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN (1-450) (HOMO SAPIENS VH (IGHV1-69*01 (94%) (IGHD)-IGHJ1