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Polymyxin B
go.drugbank.com/drugs/DB00781ApprovedInvestigationalVet approvedPolymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic[A176426,FDA Label]. … It is appropriate for treatment of infections of the urinary tract, meninges, and blood stream, caused by susceptible strains of _Pseudomonas aeruginosa_[FDA Label].
Mixtures: DAYMARK FAK-35 First AidImdevimab
go.drugbank.com/drugs/DB15940ApprovedInvestigationalCasirivimab and imdevimab are investigational recombinant human IgG1 monoclonal antibodies that, at this time, are not officially approved by the FDA. … [A221495] On November 21, 2020, the FDA authorized emergency approval of REGN-COV2 to treat mild to moderate COVID-19 in patients aged 12 years and older.
Water
go.drugbank.com/drugs/DB09145ApprovedInvestigationalWater (chemical formula: H2O) is a transparent fluid which forms the world's streams, lakes, oceans and rain, and is the major constituent of the fluids of organisms. As a chemical compound, a water molecule contains one oxygen and two h...
Sulfasalazine
go.drugbank.com/drugs/DB00795ApprovedInvestigationalIt is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis (RA). … [A255582] Although sulfasalazine is only approved by the FDA for ulcerative colitis, research have shown that sulfasalazine is also beneficial for patients with Crohn's disease.
Products: PLEON RA, AZULFIDINE RADaptomycin
go.drugbank.com/drugs/DB00080ApprovedInvestigational[A231379] Daptomycin was approved by the FDA on September 12, 2003, and is marketed under the name CUBICIN® by Cubist Pharmaceuticals LLC (Merck & Co.).[L32534]
Arsthinol
go.drugbank.com/drugs/DB08928ExperimentalConsidered well tolerated when compared to other related trivalent organoarsenicals, arsthinol has even undergone recent studies as a potential anticancer agent.
Fluocinolone acetonide
go.drugbank.com/drugs/DB00591ApprovedInvestigationalVet approved[T358] This type of device containing fluocinolone acetonide was developed by Taro Pharmaceuticals and approved by FDA in May 2016.[L4676]
Categories: Corticosteroid Hormone Receptor AgonistsAceclidine
go.drugbank.com/drugs/DB13262Approved[A274278] Aceclidine was approved the US FDA in July 2025 for the treatment of adult patients with presbyopia.[L53768] … [A274283] As compared to less selective miotics, like [pilocarpine], aceclidine's relative stimulation of the ciliary muscle is significantly less and, as such, induces far less myopic shift, lens thickening
Categories: Cholinergic Receptor AgonistSerine/threonine-protein kinase ATR
go.drugbank.com/bio_entities/BE0010060TargetHumansSerine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor (PubMed:10597277, Pu...
Synonyms: FRAP-related protein 1Polyethylene glycol 400
go.drugbank.com/drugs/DB11077ApprovedInvestigationalPolyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain various derivatives and have various functions. Because many PEG types are hydrophilic, they are favorably used as enhancers of penetrat...