Aceclidine is a topical ophthalmic muscarinic agonist used to induce miosis in order to treat presbyopia. Aceclidine is a cholinergic muscarinic agonist which began marketing in Europe in the 1970s for the treatment of glaucoma.
- Mechanism
- Curator reviewed · 4 references
Presbyopia is a common age-related condition characterized by the inability of the eye to accommodate and focus properly on objects at different distances, leading to near vision loss.
Aceclidine is a selective cholinergic muscarinic agonist that treats presbyopia by stimulating muscarinic receptors located on smooth muscles. It is a predominately pupil-selective miotic, interacting primarily with the iris with minimal ciliary muscle stimulation. This interaction causes contraction of the iris sphincter muscle, which results in a pinhole effect that extends the depth of focus and improves vision.
- Primary indication
- Aceclidine ophthalmic solution is indicated for the treatment of presbyopia in adult patients.Curator reviewed · 1 structured indication
- Formula / weight
- C9H15NO2 · 169.224 g/mol (avg)
- First approval
- United States, 2025
- Also known as
- 3-Acetoxyquinuclidine
- Brand names
Resolves to
WRJPSSPFHGNBMG-UHFFFAOYSA-NSMILESCC(=O)OC1CN2CCC1CC2What you can answer from here — as of September 13, 2026
Which drugs share a target with Aceclidine, and which of those have an active Phase 3 trial?
Create a free account or log in to explore the full data card.
Create Account