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Ergocalciferol
go.drugbank.com/drugs/DB00153ApprovedInvestigationalNutraceuticalErgocalciferol is an inactivated vitamin D analog.[A177526] It is synthesized by some plants in the presence of UVB light. … [A177637] The first approved product containing ergocalciferol under the FDA records was developed by US Pharm Holdings and was FDA approved in 1941.[L6058]
Mixtures: Cal/mag 2:1 With D, Calcium Mg and Zn Capsules With Vitamin DCategories: Diet, Food, and Nutrition, Vitamin D and AnaloguesAntithymocyte immunoglobulin (rabbit)
go.drugbank.com/drugs/DB00098ApprovedInvestigationalThymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. … Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of T-cells.
Categories: Fluids and Secretions, Amino Acids, Peptides, and ProteinsProducts: THYMOGLOBULINE 5MG/ML, Thymoglobuline 5mg/ml Powder for concentrate for solution for infusionDimercaprol
go.drugbank.com/drugs/DB06782ApprovedIt was developed as an experimental antidote against the arsenic-based poison gas Lewisite. It has been used clinically since 1949 in arsenic, cadmium and mercury poisoning. … Dimercaprol has toxic potential, and its use may be followed by a variety of adverse effects.
Categories: Compounds used in a research, industrial, or household settingInternational brands: Bal In Oil InjectionPalbociclib
go.drugbank.com/drugs/DB09073ApprovedInvestigational[A176810] Palbociclib was developed by Pfizer Inc after the discovery that identified the cyclin-dependent kinases as key regulators of cell growth. … patients based on findings from postmarketing reports and electronic health records demonstrating safety and clinical efficacy.
Categories: Antineoplastic and Immunomodulating AgentsProducts: Ibrance Capsules 100mg, IBRANCE CAPSULE 100mgBetamethasone
go.drugbank.com/drugs/DB00443ApprovedInvestigationalVet approved[A192444] It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders. … Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties.
Mixtures: Daivobet Gel 50mcg/g + 0.5mg/g, TUDERM-NCategories: Alimentary Tract and Metabolism, Sex Hormones and InsulinsGallium citrate Ga-67
go.drugbank.com/drugs/DB06784ApprovedAlthough the mechanism is unknown, gallium Ga 67 concentrates in lysosomes and is bound to a soluble intracellular protein in certain viable primary and metastatic tumors and focal sites of inflammation … Ga-67 scintigraphy (GS) cannot differentiate between tumor and acute inflammation. [NCI Thesaurus]
Categories: Inflammation and Infection DetectionProducts: GALLIUM CITRATE (GA67) INJ 37 MBQ/ML (82 MBQ), GALLIUM CITRATE (GA67) INJ 37 MBQ/ML (123 MBQ)Ifosfamide
go.drugbank.com/drugs/DB01181ApprovedInvestigationalIfosfamide is a chemotherapeutic agent chemically related to the nitrogen mustards and a synthetic analog of cyclophosphamide. It is active as an alkylating agent and an immunosuppressive agent.
Mixtures: IFEX and MESNEX, IFEX and MESNEXCategories: Antineoplastic and Immunomodulating AgentsVindesine
go.drugbank.com/drugs/DB00309ApprovedInvestigationalWithdrawnMajor side effects are myelosuppression and neurotoxicity. Vindesine is used extensively in chemotherapy protocols (antineoplastic combined chemotherapy protocols).
Categories: Antineoplastic and Immunomodulating AgentsProducts: Eldisine Inj 5mg/2mlRavulizumab
go.drugbank.com/drugs/DB11580ApprovedInvestigational[A244460] It works by blocking terminal complement-mediated inflammation, cell activation, and cell lysis in blood disorders associated with the destruction of red blood cells, thrombosis, and impaired … [A244465] Ravulizumab was first approved by the FDA on December 21, 2018, for the treatment of paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome in children and adults.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: ULTOMIRIS ® RAVULIZUMAB 100MG/ML., Ultomiris 100mg/mL Concentrate For Solution For InfusionDiethylcarbamazine
go.drugbank.com/drugs/DB00711ApprovedInvestigationalVet approvedWithdrawnAn anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.
Categories: Piperazine and Derivatives, Antiparasitic Products, Insecticides and RepellentsProducts: Hetrazan Tab 50mg