Search
Podofilox
go.drugbank.com/drugs/DB01179ApprovedA lignan found in podophyllin resin from the roots of podophyllum plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. … It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives
International brands: Podophyllotoxin 7Products: WARTEC CREAM 0.15% w/w, WARTEC SOLUTION 0.5% w/vGlucagon
go.drugbank.com/drugs/DB00040ApprovedInvestigationalGlucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia.
Products: R-GLUCAGON LILLY, GLUCAGEN HYPOKIT 1 MG ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 1 ADETNitazoxanide
go.drugbank.com/drugs/DB00507ApprovedInvestigationalVet approvedNitazoxanide is a first-line, standard treatment for illness caused by C. parvum or G. lamblia infection in healthy (not immunosuppressed) adults and children and may also be considered in the treatment … Nitazoxanide (NTZ) is a broad-spectrum anti-infective drug that markedly modulates the survival, growth, and proliferation of a range of extracellular and intracellular protozoa, helminths, anaerobic and
Categories: Heterocyclic Compounds, 1-RingProducts: N/a, VIBATRIN® 100 MG / 5 MLSelenious acid
go.drugbank.com/drugs/DB11127ApprovedSelenious acid is the acid form of sodium selenite, a form of selenium [L1910]. Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation. … Interestingly, selenium is being studied as a potential therapy in the prevention or management of atherosclerosis [L1921].
Mixtures: Vitamins C Plus E W.beta Carotene and Se, Formula F L WProducts: Micro Se, Formula-SEOctocrylene
go.drugbank.com/drugs/DB09535ApprovedOctocrylene is a compound often used as an additive in sun screen, and is thought to have skin moisturizing effects because of its emollient properties. … What makes this chemical such a popular additive to sun block, is its ability to neutralize UV radiation dissipated by sunlight, and to minimize skin damage from prolonged sun exposure.
Mixtures: Thermal S Uv SPF 20, Ponte Vedra Inn SPF 50 C/S SunscreenProducts: Panama Jack SPF 4, Panama Jack SPF 4 Dark Tanning OilLurbinectedin
go.drugbank.com/drugs/DB12674ApprovedInvestigationalthe substitution of the tetrahydroisoquinoline with a tetrahydro β‐carboline that results in increased antitumour activity of lurbinectedin as compared to its predecessor. … Lurbinectedin is a DNA alkylating agent that has been investigated in the treatment of a variety of cancers, including mesothelioma,[A214325] chronic lymphocytic leukemia (CLL),[A214328] breast cancer,
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsAcenocoumarol
go.drugbank.com/drugs/DB01418ApprovedInvestigationalAcenocoumarol is a coumarin derivative used as an anticoagulant. Coumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase. … This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes with coagulation.
Categories: 4-Hydroxycoumarins, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: 4-Hydroxy-3-(1-(4-nitrophenyl)-3-oxobutyl)-2H-1-benzopyran-2-one, 4-Hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-oneEverolimus
go.drugbank.com/drugs/DB01590ApprovedInvestigationalEverolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor. … It is currently used as an immunosuppressant to prevent rejection of organ transplants.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: 40-O-(2-hydroxyethyl)-rapamycin, 42-O-(2-Hydroxyethyl)rapamycinLevomefolic acid
go.drugbank.com/drugs/DB11256ApprovedLevomefolate is approved as a food additive and is designated a GRAS (generally regarded as safe) compound [L773]. … It is available commercially as a crystalline form of the calcium salt (Metafolin(R)), which has the stability required for use as a supplement [A19276].
Synonyms: N-[4-[[[(6S)-2-Amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-L-glutamic acid, L-5-MTHFMixtures: L-Methyl-B6-B12, L-Methyl MCLetibotulinumtoxinA
go.drugbank.com/drugs/DB16820Approved[L42330] It is a 900 kDa multimeric complex comprising a 150 kDa toxin, a 130 kDa non-toxic non-haemagglutinating protein, and various other haemagglutinins. … [A249920] LetibotulinumtoxinA is a type A botulinum neurotoxin produced from fermentation of _Clostridium botulinum_ strain CBFC26.
Categories: Botulinum Toxins, Type ASynonyms: BoNT/A-DS